Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DOCK1
  • Mouse genes Dock1
  • Rat genes Dock1
  • Zfish genes dock1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dock1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	DOCK1	IDA		Human	PMID:12134158
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:P63000	Human	PMID:12134158
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:Q92556	Human	PMID:12134158
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:P63000	Human	PMID:15247908
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:Q92556	Human	PMID:15247908
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:P63000	Human	PMID:15723800
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:Q92556	Human	PMID:15723800
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:P46108	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:P62993	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:P46108	Human	PMID:17515907
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:Q92556	Human	PMID:18768751
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:O15084	Human	PMID:19118547
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:P62993	Human	PMID:20936779
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:P62993	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:Q92556	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:P46108	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:P62993	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:Q9H7D0-1	Human	PMID:32203420
Molecular Function	GO:0005515	protein binding	DOCK1	IPI	UniProtKB:P46108	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Dock1	IPI	UniProtKB:Q3UHD1	Mouse	MGI:MGI:3764740|PMID:17960134
Molecular Function	GO:0005515	protein binding	Dock1	IPI	UniProtKB:Q8BPU7-1|UniProtKB:Q8BYZ7|UniProtKB:Q8C0C0	Mouse	MGI:MGI:3688344|PMID:15102471
Cellular Component	GO:0005737	cytoplasm	DOCK1	IDA		Human	PMID:17515907
Cellular Component	GO:0005829	cytosol	DOCK1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0032045	guanyl-nucleotide exchange factor complex	DOCK1	IDA		Human	PMID:12134158
Cellular Component	GO:0016607	nuclear speck	DOCK1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	DOCK1	IDA		Human	GO_REF:0000052
Biological Process	GO:0016477	cell migration	Dock1	IDA		Mouse	PMID:15728191
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Dock1	IGI	MGI:MGI:1343184	Mouse	PMID:24029230
Biological Process	GO:0022011	myelination in peripheral nervous system	dock1	IMP	ZFIN:ZDB-GENO-181204-4	Zfish	PMID:30089513
Biological Process	GO:0007520	myoblast fusion	dock1	IMP	ZFIN:ZDB-MRPHLNO-080109-10	Zfish	PMID:17670792
Biological Process	GO:0007520	myoblast fusion	dock1	IMP	ZFIN:ZDB-MRPHLNO-080109-8	Zfish	PMID:17670792
Biological Process	GO:0010634	positive regulation of epithelial cell migration	DOCK1	IMP		Human	PMID:19004829
Biological Process	GO:1900026	positive regulation of substrate adhesion-dependent cell spreading	DOCK1	IMP		Human	PMID:19004829

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern