Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DOCK11
  • Mouse genes Dock11
  • Rat genes Dock11
  • Zfish genes dock11
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dock11

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Dock11	IDA		Mouse	MGI:MGI:5825418|PMID:25851601
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Dock11	IDA		Mouse	MGI:MGI:5825422|PMID:22494997
Molecular Function	GO:0005085	guanyl-nucleotide exchange factor activity	Dock11	IDA		Mouse	PMID:15710388
Molecular Function	GO:0005515	protein binding	DOCK11	IPI	UniProtKB:Q9P258	Human	PMID:25074804
Molecular Function	GO:0031267	small GTPase binding	Dock11	IPI	PR:P60766	Mouse	PMID:15710388
Biological Process	GO:0001782	B cell homeostasis	Dock11	IMP		Mouse	MGI:MGI:5818419|PMID:25729399
Biological Process	GO:0002315	marginal zone B cell differentiation	Dock11	IMP		Mouse	MGI:MGI:5818419|PMID:25729399
Biological Process	GO:0051491	positive regulation of filopodium assembly	Dock11	IMP		Mouse	MGI:MGI:5825422|PMID:22494997
Biological Process	GO:0043547	positive regulation of GTPase activity	Dock11	IDA		Mouse	MGI:MGI:5825422|PMID:22494997
Biological Process	GO:0043547	positive regulation of GTPase activity	Dock11	IDA		Mouse	MGI:MGI:5825418|PMID:25851601

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern