Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DOK1
  • Mouse genes Dok1
  • Rat genes Dok1
  • Zfish genes dok1a,dok1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dok1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	DOK1	IPI	UniProtKB:P04626	Human	PMID:16273093
Molecular Function	GO:0005515	protein binding	DOK1	IPI	UniProtKB:Q9Q2G4	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	DOK1	IPI	UniProtKB:Q9JIY2	Human	PMID:22252131
Molecular Function	GO:0005515	protein binding	DOK1	IPI	UniProtKB:Q9H3Y6	Human	PMID:23822091
Molecular Function	GO:0005515	protein binding	Dok1	IPI	UniProtKB:Q99M51	Mouse	MGI:MGI:4835598|PMID:20697350
Molecular Function	GO:0005515	protein binding	Dok1	IPI	UniProtKB:Q99M51	Mouse	MGI:MGI:3046013|PMID:15148308
Molecular Function	GO:0005515	protein binding	Dok1	IPI	UniProtKB:P00520	Mouse	MGI:MGI:3046013|PMID:15148308
Molecular Function	GO:0005515	protein binding	Dok1	IPI	PR:P09581	Mouse	PMID:10585470
Cellular Component	GO:0005829	cytosol	DOK1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DOK1	IDA		Human	PMID:23822091
Biological Process	GO:0035556	intracellular signal transduction	Dok1	IPI	PR:P97797	Mouse	PMID:10585470
Biological Process	GO:0038145	macrophage colony-stimulating factor signaling pathway	Dok1	IPI	PR:P09581	Mouse	PMID:10585470
Biological Process	GO:0007265	Ras protein signal transduction	Dok1	IPI	UniProtKB:Q91YX7	Mouse	PMID:9008161
Biological Process	GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway	Dok1	IPI	PR:P07141	Mouse	PMID:10585470

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern