Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DPEP1
  • Mouse genes Dpep1
  • Rat genes Dpep1
  • Zfish genes dpep1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dpep1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008800	beta-lactamase activity	DPEP1	IDA		Human	PMID:32325220
Molecular Function	GO:0008800	beta-lactamase activity	DPEP1	IDA		Human	PMID:6334084
Molecular Function	GO:0008800	beta-lactamase activity	Dpep1	IDA		Mouse	MGI:MGI:2669357|PMID:12738806
Molecular Function	GO:0043027	cysteine-type endopeptidase inhibitor activity involved in apoptotic process	DPEP1	IMP		Human	PMID:20435919
Molecular Function	GO:0016805	dipeptidase activity	DPEP1	IDA		Human	PMID:32325220
Molecular Function	GO:0016805	dipeptidase activity	Dpep1	IMP		Mouse	MGI:MGI:6392936|PMID:31442408
Molecular Function	GO:0016805	dipeptidase activity	Dpep1	IDA		Mouse	MGI:MGI:2669357|PMID:12738806
Molecular Function	GO:0070573	metallodipeptidase activity	DPEP1	IDA		Human	PMID:12144777
Molecular Function	GO:0070573	metallodipeptidase activity	DPEP1	IDA		Human	PMID:19879002
Molecular Function	GO:0072341	modified amino acid binding	DPEP1	IDA		Human	PMID:20031578
Molecular Function	GO:0005515	protein binding	DPEP1	IPI	UniProtKB:Q96EK5	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	DPEP1	IPI	UniProtKB:Q92624	Human	PMID:25416956
Molecular Function	GO:0008270	zinc ion binding	DPEP1	IDA		Human	PMID:12144777
Molecular Function	GO:0008270	zinc ion binding	DPEP1	IDA		Human	PMID:19879002
Cellular Component	GO:0045177	apical part of cell	DPEP1	IDA		Human	PMID:20824289
Cellular Component	GO:0030054	cell junction	DPEP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0070062	extracellular exosome	DPEP1	HDA		Human	PMID:11487543
Cellular Component	GO:0070062	extracellular exosome	DPEP1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	DPEP1	HDA		Human	PMID:23533145
Cellular Component	GO:0005654	nucleoplasm	DPEP1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	DPEP1	IDA		Human	PMID:12144777
Biological Process	GO:0016999	antibiotic metabolic process	DPEP1	IDA		Human	PMID:6334084
Biological Process	GO:0016999	antibiotic metabolic process	DPEP1	IDA		Human	PMID:8737157
Biological Process	GO:0016999	antibiotic metabolic process	Dpep1	IDA		Mouse	MGI:MGI:2669357|PMID:12738806
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	DPEP1	IDA		Human	PMID:20435919
Biological Process	GO:0006751	glutathione catabolic process	Dpep1	IMP		Mouse	MGI:MGI:1203838|PMID:9560193
Biological Process	GO:0050667	homocysteine metabolic process	DPEP1	IDA		Human	PMID:20031578
Biological Process	GO:0006954	inflammatory response	Dpep1	IMP		Mouse	MGI:MGI:6392936|PMID:31442408
Biological Process	GO:1901749	leukotriene D4 catabolic process	DPEP1	IDA		Human	PMID:32325220
Biological Process	GO:0006691	leukotriene metabolic process	Dpep1	IMP		Mouse	MGI:MGI:1203838|PMID:9560193
Biological Process	GO:0006691	leukotriene metabolic process	Dpep1	IDA		Mouse	MGI:MGI:2669357|PMID:12738806
Biological Process	GO:0043066	negative regulation of apoptotic process	DPEP1	IMP		Human	PMID:20435919
Biological Process	GO:0030336	negative regulation of cell migration	DPEP1	IMP		Human	PMID:20824289
Biological Process	GO:0043154	negative regulation of cysteine-type endopeptidase activity involved in apoptotic process	DPEP1	IMP		Human	PMID:20435919
Biological Process	GO:0030593	neutrophil chemotaxis	Dpep1	IMP		Mouse	MGI:MGI:6392936|PMID:31442408

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern