Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DPP4
  • Mouse genes Dpp4
  • Rat genes Dpp4
  • Zfish genes dpp4
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dpp4

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045499	chemorepellent activity	DPP4	IDA		Human	PMID:23677473
Molecular Function	GO:0045499	chemorepellent activity	DPP4	IMP		Human	PMID:23677473
Molecular Function	GO:0005518	collagen binding	Dpp4	IDA		Rat	PMID:8526932|RGD:1626468
Molecular Function	GO:0008239	dipeptidyl-peptidase activity	DPP4	IDA		Human	PMID:10593948
Molecular Function	GO:0008239	dipeptidyl-peptidase activity	DPP4	IDA		Human	PMID:14684150
Molecular Function	GO:0008239	dipeptidyl-peptidase activity	DPP4	IDA		Human	PMID:16651416
Molecular Function	GO:0008239	dipeptidyl-peptidase activity	DPP4	IDA		Human	PMID:17549790
Molecular Function	GO:0008239	dipeptidyl-peptidase activity	DPP4	IDA		Human	PMID:27198182
Molecular Function	GO:0008239	dipeptidyl-peptidase activity	Dpp4	IDA		Rat	PMID:10931192|RGD:1626465
Molecular Function	GO:0008239	dipeptidyl-peptidase activity	Dpp4	IDA		Rat	PMID:17415460|RGD:1626457
Molecular Function	GO:0008239	dipeptidyl-peptidase activity	Dpp4	IMP		Rat	PMID:9210490|RGD:1626463
Molecular Function	GO:0042802	identical protein binding	DPP4	IPI	UniProtKB:P27487	Human	PMID:22001206
Molecular Function	GO:0042802	identical protein binding	Dpp4	IPI	RGD:2515	Rat	PMID:10931192|RGD:1626465
Molecular Function	GO:0042802	identical protein binding	Dpp4	IPI	RGD:2515	Rat	PMID:12705886|RGD:1626462
Molecular Function	GO:0042802	identical protein binding	Dpp4	IMP		Rat	PMID:9210490|RGD:1626463
Molecular Function	GO:0042277	peptide binding	Dpp4	IDA		Rat	PMID:17415460|RGD:1626457
Molecular Function	GO:0002020	protease binding	DPP4	IPI	UniProtKB:Q12884	Human	PMID:16651416
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:P00813	Human	PMID:14684150
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:Q03135	Human	PMID:17287217
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:Q9BXL7	Human	PMID:17287217
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:P51654	Human	PMID:17549790
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:O14625	Human	PMID:18275857
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:P02778	Human	PMID:18275857
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:P19875	Human	PMID:18275857
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:P51671	Human	PMID:18275857
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:Q07325	Human	PMID:18275857
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:O14625	Human	PMID:21314817
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:P01275	Human	PMID:21314817
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:P01282	Human	PMID:21314817
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:P02778	Human	PMID:21314817
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:P19875	Human	PMID:21314817
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:P51671	Human	PMID:21314817
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:Q07325	Human	PMID:21314817
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:P56658	Human	PMID:22001206
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:K0BRG7	Human	PMID:23486063
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:K0BRG7	Human	PMID:23831647
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:R9UQ53	Human	PMID:23835475
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:K9N5Q8	Human	PMID:25461530
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:A0A2R4KP93	Human	PMID:29669833
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:K9N5Q8	Human	PMID:29669833
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:K9N5Q8	Human	PMID:32203189
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:K9N5Q8	Human	PMID:32275855
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:Q14416	Human	PMID:34903715
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:P00813	Human	PMID:7594462
Molecular Function	GO:0005515	protein binding	DPP4	IPI	UniProtKB:P00813	Human	PMID:8101391
Molecular Function	GO:0042803	protein homodimerization activity	DPP4	IPI	UniProtKB:P27487	Human	PMID:14684150
Molecular Function	GO:0042803	protein homodimerization activity	DPP4	IPI	UniProtKB:P27487	Human	PMID:15448155
Molecular Function	GO:0004252	serine-type endopeptidase activity	DPP4	EXP		Human	PMID:8100523
Molecular Function	GO:0004252	serine-type endopeptidase activity	DPP4	EXP		Human	PMID:8798518
Molecular Function	GO:0008236	serine-type peptidase activity	DPP4	IDA		Human	PMID:14684150
Molecular Function	GO:0005102	signaling receptor binding	DPP4	IPI	UniProtKB:P11717	Human	PMID:10900005
Molecular Function	GO:0001618	virus receptor activity	DPP4	IDA		Human	PMID:23486063
Cellular Component	GO:0016324	apical plasma membrane	DPP4	IDA		Human	PMID:15052268
Cellular Component	GO:0009986	cell surface	DPP4	IDA		Human	PMID:10900005
Cellular Component	GO:0009986	cell surface	DPP4	IDA		Human	PMID:11772392
Cellular Component	GO:0009986	cell surface	DPP4	IDA		Human	PMID:7594462
Cellular Component	GO:0009986	cell surface	DPP4	IDA		Human	PMID:8101391
Cellular Component	GO:0009986	cell surface	Dpp4	IDA		Rat	PMID:10931192|RGD:1626465
Cellular Component	GO:0030139	endocytic vesicle	DPP4	IDA		Human	PMID:10900005
Cellular Component	GO:0005783	endoplasmic reticulum	Dpp4	IDA		Rat	PMID:10931192|RGD:1626465
Cellular Component	GO:0070062	extracellular exosome	DPP4	HDA		Human	PMID:11487543
Cellular Component	GO:0070062	extracellular exosome	DPP4	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	DPP4	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	DPP4	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	DPP4	HDA		Human	PMID:21362503
Cellular Component	GO:0070062	extracellular exosome	DPP4	HDA		Human	PMID:23533145
Cellular Component	GO:0005925	focal adhesion	DPP4	HDA		Human	PMID:21423176
Cellular Component	GO:0005794	Golgi apparatus	Dpp4	IDA		Rat	PMID:10931192|RGD:1626465
Cellular Component	GO:0046581	intercellular canaliculus	Dpp4	IDA		Mouse	PMID:12068294
Cellular Component	GO:0030027	lamellipodium	DPP4	IDA		Human	PMID:16651416
Cellular Component	GO:0005765	lysosomal membrane	DPP4	HDA		Human	PMID:17897319
Cellular Component	GO:0016020	membrane	DPP4	HDA		Human	PMID:19946888
Cellular Component	GO:0005886	plasma membrane	DPP4	IDA		Human	PMID:16670267
Cellular Component	GO:0005886	plasma membrane	Dpp4	IDA		Rat	PMID:8526932|RGD:1626468
Biological Process	GO:0002337	B-1a B cell differentiation	Dpp4	IMP		Rat	PMID:19327106|RGD:41408336
Biological Process	GO:0001662	behavioral fear response	Dpp4	IMP	MGI:MGI:2150161	Mouse	PMID:16712972
Biological Process	GO:0043542	endothelial cell migration	DPP4	IDA		Human	PMID:16651416
Biological Process	GO:0051234	establishment of localization	Dpp4	IMP		Rat	PMID:15606609|RGD:1626458
Biological Process	GO:0035641	locomotory exploration behavior	Dpp4	IMP	MGI:MGI:2150161	Mouse	PMID:16712972
Biological Process	GO:0010716	negative regulation of extracellular matrix disassembly	DPP4	IDA		Human	PMID:16651416
Biological Process	GO:0090024	negative regulation of neutrophil chemotaxis	DPP4	IMP		Human	PMID:23677473
Biological Process	GO:0008284	positive regulation of cell population proliferation	DPP4	IDA		Human	PMID:17549790
Biological Process	GO:0002717	positive regulation of natural killer cell mediated immunity	Dpp4	IMP		Rat	PMID:19327106|RGD:41408336
Biological Process	GO:0030163	protein catabolic process	Dpp4	IDA		Rat	PMID:17415460|RGD:1626457
Biological Process	GO:0006508	proteolysis	DPP4	IDA		Human	PMID:27198182
Biological Process	GO:0036343	psychomotor behavior	Dpp4	IMP	MGI:MGI:2150161	Mouse	PMID:16712972
Biological Process	GO:0033632	regulation of cell-cell adhesion mediated by integrin	DPP4	IDA		Human	PMID:11772392
Biological Process	GO:0002709	regulation of T cell mediated immunity	Dpp4	IMP		Rat	PMID:15606609|RGD:1626458
Biological Process	GO:0001666	response to hypoxia	DPP4	IDA		Human	PMID:16670267
Biological Process	GO:0042110	T cell activation	DPP4	IDA		Human	PMID:7594462
Biological Process	GO:0031295	T cell costimulation	DPP4	IDA		Human	PMID:10900005
Biological Process	GO:0031295	T cell costimulation	DPP4	IDA		Human	PMID:17287217

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern