Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DPP6
  • Mouse genes Dpp6
  • Rat genes Dpp6
  • Zfish genes dpp6a,dpp6b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dpp6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0015459	potassium channel regulator activity	DPP6	IDA		Human	PMID:18364354
Molecular Function	GO:0015459	potassium channel regulator activity	Dpp6	IDA		Mouse	MGI:MGI:5616307|PMID:22311982
Molecular Function	GO:0005515	protein binding	Dpp6	IPI	PR:P04925	Mouse	PMID:24225951
Molecular Function	GO:0005515	protein binding	Dpp6	IPI	PR:Q9QUG3	Mouse	PMID:24225951
Molecular Function	GO:0005515	protein binding	Dpp6	IPI	RGD:68393	Rat	PMID:12575952|RGD:5687190
Cellular Component	GO:0009986	cell surface	Dpp6	IDA		Rat	PMID:11173531|RGD:5687191
Cellular Component	GO:0016020	membrane	DPP6	IDA		Human	PMID:18364354
Cellular Component	GO:0016020	membrane	Dpp6	IDA		Mouse	PMID:24225951
Cellular Component	GO:0043025	neuronal cell body	Dpp6	IDA		Rat	PMID:12575952|RGD:5687190
Cellular Component	GO:0005886	plasma membrane	Dpp6	IDA		Mouse	MGI:MGI:5616307|PMID:22311982
Cellular Component	GO:0008076	voltage-gated potassium channel complex	DPP6	IDA		Human	PMID:18364354
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Dpp6	IDA		Mouse	MGI:MGI:5616313|PMID:19713751
Cellular Component	GO:0008076	voltage-gated potassium channel complex	Dpp6	IDA		Rat	PMID:12575952|RGD:5687190
Biological Process	GO:0051649	establishment of localization in cell	Dpp6	IMP	MGI:MGI:5302080	Mouse	PMID:21943606
Biological Process	GO:0019228	neuronal action potential	Dpp6	IMP		Mouse	PMID:20573902
Biological Process	GO:1901381	positive regulation of potassium ion transmembrane transport	Dpp6	IMP	MGI:MGI:5302080	Mouse	PMID:21943606
Biological Process	GO:0043268	positive regulation of potassium ion transport	Dpp6	IMP		Rat	PMID:12575952|RGD:5687190
Biological Process	GO:1903078	positive regulation of protein localization to plasma membrane	Dpp6	IDA		Rat	PMID:15671030|RGD:10047339
Biological Process	GO:0071805	potassium ion transmembrane transport	Dpp6	IMP	MGI:MGI:5302080	Mouse	PMID:21943606
Biological Process	GO:0072659	protein localization to plasma membrane	Dpp6	IDA		Mouse	MGI:MGI:5616307|PMID:22311982
Biological Process	GO:0042391	regulation of membrane potential	Dpp6	IMP	MGI:MGI:5302080	Mouse	PMID:21943606
Biological Process	GO:0042391	regulation of membrane potential	Dpp6	IMP		Mouse	PMID:20573902
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport	DPP6	IDA		Human	PMID:18364354
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport	Dpp6	IDA		Mouse	MGI:MGI:5616307|PMID:22311982
Biological Process	GO:1901379	regulation of potassium ion transmembrane transport	Dpp6	IGI	MGI:MGI:97769	Mouse	PMID:24225951
Biological Process	GO:0043266	regulation of potassium ion transport	Dpp6	IMP		Mouse	PMID:20573902

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern