Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DPYS
  • Mouse genes Dpys
  • Rat genes Dpys
  • Zfish genes dpys
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dpys

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016597	amino acid binding	Dpys	IDA		Rat	PMID:8307005|RGD:1624990
Molecular Function	GO:0004157	dihydropyrimidinase activity	DPYS	IDA		Human	PMID:10410956
Molecular Function	GO:0004157	dihydropyrimidinase activity	DPYS	IMP		Human	PMID:18075467
Molecular Function	GO:0004157	dihydropyrimidinase activity	DPYS	IDA		Human	PMID:9718352
Molecular Function	GO:0004157	dihydropyrimidinase activity	Dpys	IDA		Mouse	PMID:5472365
Molecular Function	GO:0004157	dihydropyrimidinase activity	Dpys	IDA		Rat	PMID:7626590|RGD:1624989
Molecular Function	GO:0004157	dihydropyrimidinase activity	Dpys	IDA		Rat	PMID:8307005|RGD:1624990
Molecular Function	GO:0042802	identical protein binding	Dpys	IPI	RGD:68376	Rat	PMID:8307005|RGD:1624990
Molecular Function	GO:0042802	identical protein binding	Dpys	IPI	UniProtKB:Q63150	Rat	PMID:8307005|RGD:1624990
Molecular Function	GO:0051219	phosphoprotein binding	Dpys	IPI	UniProtKB:Q9DDZ6	Mouse	MGI:MGI:1927681|PMID:10956643
Molecular Function	GO:0005515	protein binding	DPYS	IPI	UniProtKB:Q92624	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	DPYS	IPI	UniProtKB:O14645	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DPYS	IPI	UniProtKB:O14901	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DPYS	IPI	UniProtKB:P01112	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DPYS	IPI	UniProtKB:P06396	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DPYS	IPI	UniProtKB:P22607	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DPYS	IPI	UniProtKB:P28329-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DPYS	IPI	UniProtKB:P46379-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DPYS	IPI	UniProtKB:Q14957	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DPYS	IPI	UniProtKB:Q9BVL2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DPYS	IPI	UniProtKB:Q9UMX0	Human	PMID:32814053
Molecular Function	GO:0002059	thymine binding	Dpys	IDA		Rat	PMID:8307005|RGD:1624990
Molecular Function	GO:0002058	uracil binding	Dpys	IDA		Rat	PMID:8307005|RGD:1624990
Molecular Function	GO:0008270	zinc ion binding	Dpys	IMP		Rat	PMID:7626590|RGD:1624989
Molecular Function	GO:0008270	zinc ion binding	Dpys	IDA		Rat	PMID:8307005|RGD:1624990
Cellular Component	GO:0005829	cytosol	Dpys	IDA		Mouse	PMID:5472365
Cellular Component	GO:0005829	cytosol	Dpys	IDA		Rat	PMID:8307005|RGD:1624990
Cellular Component	GO:0070062	extracellular exosome	DPYS	HDA		Human	PMID:19056867
Cellular Component	GO:0032991	protein-containing complex	Dpys	IDA		Rat	PMID:8307005|RGD:1624990
Biological Process	GO:0019482	beta-alanine metabolic process	Dpys	IDA		Rat	PMID:8307005|RGD:1624990
Biological Process	GO:0006248	CMP catabolic process	Dpys	IDA		Mouse	PMID:5472365
Biological Process	GO:0006249	dCMP catabolic process	Dpys	IDA		Mouse	PMID:5472365
Biological Process	GO:0046079	dUMP catabolic process	Dpys	IDA		Mouse	PMID:5472365
Biological Process	GO:0006208	pyrimidine nucleobase catabolic process	DPYS	IDA		Human	PMID:9718352
Biological Process	GO:0006210	thymine catabolic process	Dpys	IDA		Rat	PMID:8307005|RGD:1624990
Biological Process	GO:0046050	UMP catabolic process	Dpys	IDA		Mouse	PMID:5472365
Biological Process	GO:0006212	uracil catabolic process	DPYS	IDA		Human	PMID:10410956
Biological Process	GO:0006212	uracil catabolic process	DPYS	IMP		Human	PMID:18075467
Biological Process	GO:0006212	uracil catabolic process	Dpys	IDA		Rat	PMID:8307005|RGD:1624990
Biological Process	GO:0019860	uracil metabolic process	Dpys	IDA		Rat	PMID:7626590|RGD:1624989
Biological Process	GO:0019860	uracil metabolic process	Dpys	IDA		Rat	PMID:8307005|RGD:1624990

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern