Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DSC1
  • Mouse genes Dsc1
  • Rat genes Dsc1
  • Zfish genes dsc2l
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dsc1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	DSC1	IPI	UniProtKB:Q02413	Human	PMID:19136012
Molecular Function	GO:0005515	protein binding	Dsc1	IPI	PR:Q02257	Mouse	PMID:12847106
Molecular Function	GO:0005515	protein binding	Dsc1	IPI	PR:P97350	Mouse	PMID:14673151
Molecular Function	GO:0005515	protein binding	Dsc1	IPI	PR:Q02257	Mouse	PMID:14673151
Cellular Component	GO:0030057	desmosome	Dsc1	IDA		Mouse	PMID:14673151
Cellular Component	GO:0070062	extracellular exosome	DSC1	HDA		Human	PMID:23533145
Biological Process	GO:0060027	convergent extension involved in gastrulation	dsc2l	IMP	ZFIN:ZDB-MRPHLNO-120227-3	Zfish	PMID:22235774
Biological Process	GO:0002159	desmosome assembly	dsc2l	IMP	ZFIN:ZDB-MRPHLNO-120227-3	Zfish	PMID:22235774
Biological Process	GO:0055113	epiboly involved in gastrulation with mouth forming second	dsc2l	IMP	ZFIN:ZDB-MRPHLNO-120227-3	Zfish	PMID:22235774
Biological Process	GO:0060047	heart contraction	dsc2l	IMP	ZFIN:ZDB-MRPHLNO-211213-2	Zfish	PMID:33784018
Biological Process	GO:0060047	heart contraction	dsc2l	IMP	ZFIN:ZDB-MRPHLNO-211213-1	Zfish	PMID:33784018
Biological Process	GO:0007507	heart development	dsc2l	IMP	ZFIN:ZDB-MRPHLNO-070206-2	Zfish	PMID:17186466

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern