Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DSCAM
  • Mouse genes Dscam
  • Rat genes Dscam
  • Zfish genes dscama,dscamb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dscam

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:1990890	netrin receptor binding	DSCAM	IPI	UniProtKB:O95185	Human	PMID:22685302
Molecular Function	GO:1990890	netrin receptor binding	Dscam	IPI	UniProtKB:O08747	Mouse	MGI:MGI:6274971|PMID:22685302
Molecular Function	GO:0005515	protein binding	DSCAM	IPI	UniProtKB:O95631	Human	PMID:19196994
Molecular Function	GO:0005515	protein binding	DSCAM	IPI	UniProtKB:Q8WWB5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Dscam	IPI	UniProtKB:P70211|UniProtKB:Q63155|UniProtKB:Q90922	Mouse	MGI:MGI:3829111|PMID:18585357
Molecular Function	GO:0005515	protein binding	Dscam	IPI	UniProtKB:O09118|UniProtKB:P43146	Mouse	MGI:MGI:3829111|PMID:18585357
Molecular Function	GO:1990782	protein tyrosine kinase binding	Dscam	IPI	UniProtKB:P34152|UniProtKB:P39688	Mouse	MGI:MGI:6274971|PMID:22685302
Cellular Component	GO:0030424	axon	Dscam	IDA		Mouse	MGI:MGI:4441243|PMID:19196994
Cellular Component	GO:0030424	axon	Dscam	IDA		Mouse	MGI:MGI:6274971|PMID:22685302
Cellular Component	GO:0030425	dendrite	Dscam	IDA		Mouse	MGI:MGI:6274971|PMID:22685302
Cellular Component	GO:0030426	growth cone	Dscam	IDA		Mouse	MGI:MGI:6274971|PMID:22685302
Cellular Component	GO:0030426	growth cone	Dscam	IDA		Mouse	MGI:MGI:4441243|PMID:19196994
Cellular Component	GO:0043025	neuronal cell body	Dscam	IDA		Mouse	MGI:MGI:6274971|PMID:22685302
Cellular Component	GO:0005886	plasma membrane	Dscam	IDA		Mouse	MGI:MGI:4441243|PMID:19196994
Cellular Component	GO:0005886	plasma membrane	dscama	IDA		Zfish	PMID:15708557
Biological Process	GO:0007411	axon guidance	Dscam	IDA		Mouse	MGI:MGI:6274971|PMID:22685302
Biological Process	GO:0007411	axon guidance	Dscam	IGI	UniProtKB:O08747	Mouse	MGI:MGI:6274971|PMID:22685302
Biological Process	GO:0042074	cell migration involved in gastrulation	dscama	IMP	ZFIN:ZDB-MRPHLNO-050311-1	Zfish	PMID:15708557
Biological Process	GO:0048813	dendrite morphogenesis	Dscam	IMP	MGI:MGI:3761008	Mouse	PMID:18216855
Biological Process	GO:0070593	dendrite self-avoidance	Dscam	IMP		Mouse	MGI:MGI:4413613|PMID:19945391
Biological Process	GO:0048484	enteric nervous system development	dscama	IMP	ZFIN:ZDB-MRPHLNO-111031-3	Zfish	PMID:34136475
Biological Process	GO:0048484	enteric nervous system development	dscamb	IMP	ZFIN:ZDB-MRPHLNO-220426-1	Zfish	PMID:34136475
Biological Process	GO:0007626	locomotory behavior	Dscam	IMP	MGI:MGI:3761008	Mouse	PMID:18216855
Biological Process	GO:0007162	negative regulation of cell adhesion	Dscam	IMP		Mouse	MGI:MGI:4413613|PMID:19945391
Biological Process	GO:0038007	netrin-activated signaling pathway	Dscam	IGI	UniProtKB:O08747	Mouse	MGI:MGI:6274971|PMID:22685302
Biological Process	GO:0038007	netrin-activated signaling pathway	Dscam	IDA		Mouse	MGI:MGI:6274971|PMID:22685302
Biological Process	GO:0048842	positive regulation of axon extension involved in axon guidance	DSCAM	IDA		Human	PMID:18585357
Biological Process	GO:0048842	positive regulation of axon extension involved in axon guidance	Dscam	IDA		Mouse	MGI:MGI:3829111|PMID:18585357
Biological Process	GO:0048842	positive regulation of axon extension involved in axon guidance	Dscam	IMP		Rat	PMID:18585357|RGD:8553710
Biological Process	GO:0042327	positive regulation of phosphorylation	DSCAM	IDA		Human	PMID:19196994
Biological Process	GO:0060060	post-embryonic retina morphogenesis in camera-type eye	Dscam	IMP	MGI:MGI:3761008	Mouse	PMID:18216855

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern