Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DSG1
  • Mouse genes Dsg1b
  • Rat genes Dsg1
  • Zfish genes si:ch73-74h11.1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dsg1b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045295	gamma-catenin binding	DSG1	IPI	UniProtKB:P14923	Human	PMID:7983064
Molecular Function	GO:0005515	protein binding	DSG1	IPI	UniProtKB:Q99959	Human	PMID:11790773
Molecular Function	GO:0005515	protein binding	DSG1	IPI	UniProtKB:P14923	Human	PMID:19136012
Molecular Function	GO:0005515	protein binding	DSG1	IPI	UniProtKB:P15924	Human	PMID:19136012
Molecular Function	GO:0005515	protein binding	DSG1	IPI	UniProtKB:Q02413	Human	PMID:19136012
Molecular Function	GO:0005515	protein binding	DSG1	IPI	UniProtKB:Q08554	Human	PMID:19136012
Molecular Function	GO:0005515	protein binding	DSG1	IPI	UniProtKB:Q13835	Human	PMID:19136012
Molecular Function	GO:0005515	protein binding	DSG1	IPI	UniProtKB:P19712:PRO_0000038050	Human	PMID:24965446
Cellular Component	GO:0016324	apical plasma membrane	Dsg1	IDA		Rat	PMID:10937559|RGD:2316256
Cellular Component	GO:0005911	cell-cell junction	DSG1	IDA		Human	PMID:7983064
Cellular Component	GO:0005737	cytoplasm	DSG1	IDA		Human	PMID:34368962
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	DSG1	IDA		Human	PMID:7983064
Cellular Component	GO:0030057	desmosome	DSG1	IDA		Human	PMID:34368962
Cellular Component	GO:0030057	desmosome	Dsg1b	IDA		Mouse	PMID:12631242
Cellular Component	GO:0030057	desmosome	Dsg1b	IDA		Mouse	PMID:14673151
Cellular Component	GO:0016328	lateral plasma membrane	Dsg1	IDA		Rat	PMID:15530549|RGD:1581662
Cellular Component	GO:0005634	nucleus	DSG1	IDA		Human	PMID:34368962
Biological Process	GO:0060135	maternal process involved in female pregnancy	Dsg1	IEP		Rat	PMID:15530549|RGD:1581662
Biological Process	GO:0050821	protein stabilization	DSG1	IDA		Human	PMID:7983064
Biological Process	GO:0032570	response to progesterone	Dsg1	IEP		Rat	PMID:15530549|RGD:1581662

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern