Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DSG2
  • Mouse genes Dsg2
  • Rat genes Dsg2
  • Zfish genes si:ch73-74h11.1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dsg2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0050839	cell adhesion molecule binding	DSG2	IPI	UniProtKB:P14923	Human	PMID:17559062
Molecular Function	GO:0005515	protein binding	DSG2	IPI	UniProtKB:Q99959	Human	PMID:11790773
Cellular Component	GO:0016324	apical plasma membrane	Dsg2	IDA		Rat	PMID:10937559|RGD:2316256
Cellular Component	GO:0030054	cell junction	DSG2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0009986	cell surface	DSG2	HDA		Human	PMID:19581412
Cellular Component	GO:0030057	desmosome	DSG2	IDA		Human	PMID:23381804
Cellular Component	GO:0030057	desmosome	Dsg2	IDA		Mouse	PMID:22274697
Cellular Component	GO:0030057	desmosome	Dsg2	IDA		Mouse	PMID:14673151
Cellular Component	GO:0030057	desmosome	Dsg2	IDA		Mouse	PMID:9864371
Cellular Component	GO:0030057	desmosome	Dsg2	IDA		Mouse	PMID:15775979
Cellular Component	GO:0030057	desmosome	Dsg2	IDA		Mouse	PMID:12631242
Cellular Component	GO:0070062	extracellular exosome	DSG2	HDA		Human	PMID:19199708
Cellular Component	GO:0014704	intercalated disc	DSG2	IDA		Human	PMID:23381804
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	DSG2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016328	lateral plasma membrane	Dsg2	IDA		Rat	PMID:15530549|RGD:1581662
Cellular Component	GO:0005886	plasma membrane	DSG2	IDA		Human	PMID:17559062
Cellular Component	GO:0005886	plasma membrane	DSG2	IDA		Human	PMID:20859650
Biological Process	GO:0086073	bundle of His cell-Purkinje myocyte adhesion involved in cell communication	DSG2	IMP		Human	PMID:16505173
Biological Process	GO:0007155	cell adhesion	DSG2	IDA		Human	PMID:17559062
Biological Process	GO:0002934	desmosome organization	DSG2	IMP		Human	PMID:16505173
Biological Process	GO:0007156	homophilic cell adhesion via plasma membrane adhesion molecules	DSG2	IDA		Human	PMID:17559062
Biological Process	GO:0060135	maternal process involved in female pregnancy	Dsg2	IEP		Rat	PMID:15530549|RGD:1581662
Biological Process	GO:0003165	Purkinje myocyte development	DSG2	IMP		Human	PMID:16505173
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	DSG2	IMP		Human	PMID:16505173
Biological Process	GO:0086091	regulation of heart rate by cardiac conduction	DSG2	IMP		Human	PMID:23381804
Biological Process	GO:0098911	regulation of ventricular cardiac muscle cell action potential	DSG2	IMP		Human	PMID:16505173
Biological Process	GO:0098911	regulation of ventricular cardiac muscle cell action potential	DSG2	IMP		Human	PMID:23381804
Biological Process	GO:0032570	response to progesterone	Dsg2	IEP		Rat	PMID:15530549|RGD:1581662

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern