Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DST
  • Mouse genes Dst
  • Rat genes Dst
  • Zfish genes dst
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dst

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005178	integrin binding	DST	IPI	UniProtKB:P16144	Human	PMID:11375975
Molecular Function	GO:0051010	microtubule plus-end binding	DST	IDA		Human	PMID:19632184
Molecular Function	GO:0005515	protein binding	DST	IPI	UniProtKB:Q96RT1	Human	PMID:11375975
Molecular Function	GO:0005515	protein binding	DST	IPI	UniProtKB:Q9UMD9	Human	PMID:12482924
Molecular Function	GO:0005515	protein binding	DST	IPI	UniProtKB:Q9NRI5	Human	PMID:17043677
Molecular Function	GO:0005515	protein binding	DST	IPI	UniProtKB:Q15691	Human	PMID:19632184
Molecular Function	GO:0005515	protein binding	DST	IPI	UniProtKB:Q15149	Human	PMID:19932097
Molecular Function	GO:0005515	protein binding	DST	IPI	UniProtKB:P29991:PRO_0000037946	Human	PMID:21911577
Molecular Function	GO:0005515	protein binding	DST	IPI	UniProtKB:Q61166	Human	PMID:22995871
Molecular Function	GO:0005515	protein binding	DST	IPI	UniProtKB:Q9UKG1	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	DST	IPI	UniProtKB:Q15691	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	DST	IPI	UniProtKB:Q61166	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	DST	IPI	UniProtKB:Q15691	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	DST	IPI	UniProtKB:Q9NRI5	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	Dst	IPI	UniProtKB:O08788	Mouse	MGI:MGI:2679412|PMID:14581450
Molecular Function	GO:0005515	protein binding	Dst	IPI	UniProtKB:P21807	Mouse	MGI:MGI:1330496|PMID:9971739
Molecular Function	GO:0005515	protein binding	Dst	IPI	UniProtKB:Q8BHE4	Mouse	MGI:MGI:3703204|PMID:17287360
Molecular Function	GO:0005515	protein binding	Dst	IPI	UniProtKB:Q4FZC9	Mouse	MGI:MGI:3807136|PMID:18638474
Molecular Function	GO:0005515	protein binding	Dst	IPI	UniProtKB:Q9JI91	Mouse	PMID:19932097
Molecular Function	GO:0005515	protein binding	Dst	IPI	UniProtKB:Q9QXS1	Mouse	PMID:19932097
Molecular Function	GO:0005515	protein binding	Dst	IPI	PR:P10126	Mouse	PMID:21689717
Molecular Function	GO:0042803	protein homodimerization activity	Dst	IDA		Mouse	MGI:MGI:2681367|PMID:14576348
Cellular Component	GO:0015629	actin cytoskeleton	Dst	IDA		Mouse	MGI:MGI:2681367|PMID:14576348
Cellular Component	GO:0015629	actin cytoskeleton	Dst	IDA		Mouse	MGI:MGI:3612006|PMID:16289082
Cellular Component	GO:0030424	axon	Dst	IDA		Mouse	MGI:MGI:3703204|PMID:17287360
Cellular Component	GO:0031252	cell leading edge	DST	IDA		Human	PMID:19403692
Cellular Component	GO:0005737	cytoplasm	DST	IDA		Human	PMID:11751855
Cellular Component	GO:0005737	cytoplasm	Dst	IDA		Mouse	MGI:MGI:4421360|PMID:19932097
Cellular Component	GO:0009898	cytoplasmic side of plasma membrane	Dst	IDA		Mouse	MGI:MGI:3612006|PMID:16289082
Cellular Component	GO:0031410	cytoplasmic vesicle	DST	IDA		Human	PMID:14581450
Cellular Component	GO:0005829	cytosol	DST	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Dst	IDA		Mouse	MGI:MGI:3807136|PMID:18638474
Cellular Component	GO:0005925	focal adhesion	DST	HDA		Human	PMID:21423176
Cellular Component	GO:0005925	focal adhesion	Dst	IDA		Mouse	MGI:MGI:3612006|PMID:16289082
Cellular Component	GO:0005925	focal adhesion	Dst	IDA		Mouse	MGI:MGI:2681367|PMID:14576348
Cellular Component	GO:0031673	H zone	Dst	IDA		Mouse	MGI:MGI:4439443|PMID:20209123
Cellular Component	GO:0030056	hemidesmosome	Dst	IDA		Mouse	MGI:MGI:72689|PMID:7736575
Cellular Component	GO:0030056	hemidesmosome	Dst	IDA		Mouse	PMID:8707838
Cellular Component	GO:0014704	intercalated disc	Dst	IDA		Mouse	MGI:MGI:4421360|PMID:19932097
Cellular Component	GO:0005882	intermediate filament	Dst	IDA		Mouse	PMID:19932097
Cellular Component	GO:0016020	membrane	Dst	IDA		Mouse	MGI:MGI:3612006|PMID:16289082
Cellular Component	GO:0015630	microtubule cytoskeleton	DST	IDA		Human	GO_REF:0000052
Cellular Component	GO:0015630	microtubule cytoskeleton	Dst	IDA		Mouse	MGI:MGI:3612006|PMID:16289082
Cellular Component	GO:0035371	microtubule plus-end	DST	IDA		Human	PMID:19632184
Cellular Component	GO:0005635	nuclear envelope	Dst	IDA		Mouse	MGI:MGI:3807136|PMID:18638474
Cellular Component	GO:0005654	nucleoplasm	DST	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DST	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	Dst	IDA		Mouse	MGI:MGI:2681367|PMID:14576348
Cellular Component	GO:0005634	nucleus	Dst	IDA		Mouse	MGI:MGI:3612006|PMID:16289082
Cellular Component	GO:0097038	perinuclear endoplasmic reticulum	Dst	IDA		Mouse	MGI:MGI:3612006|PMID:16289082
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Dst	IDA		Mouse	MGI:MGI:3612006|PMID:16289082
Cellular Component	GO:0014069	postsynaptic density	Dst	IDA		Mouse	PMID:17114649
Cellular Component	GO:0042383	sarcolemma	Dst	IDA		Mouse	MGI:MGI:4439443|PMID:20209123
Cellular Component	GO:0001725	stress fiber	Dst	IDA		Mouse	MGI:MGI:2681367|PMID:14576348
Cellular Component	GO:0045098	type III intermediate filament	Dst	IDA		Mouse	PMID:19932097
Cellular Component	GO:0030018	Z disc	Dst	IDA		Mouse	MGI:MGI:4439443|PMID:20209123
Cellular Component	GO:0030018	Z disc	Dst	IDA		Mouse	PMID:19932097
Biological Process	GO:0007409	axonogenesis	Dst	IMP	MGI:MGI:1856672	Mouse	PMID:1634998
Biological Process	GO:0007409	axonogenesis	Dst	IMP	MGI:MGI:1856673	Mouse	PMID:1634998
Biological Process	GO:0048870	cell motility	DST	IMP		Human	PMID:19403692
Biological Process	GO:0007010	cytoskeleton organization	DST	IMP		Human	PMID:19403692
Biological Process	GO:0007010	cytoskeleton organization	Dst	IMP	MGI:MGI:1859982	Mouse	PMID:19932097
Biological Process	GO:0045104	intermediate filament cytoskeleton organization	DST	IEP		Human	PMID:11751855
Biological Process	GO:0046907	intracellular transport	Dst	IDA		Mouse	MGI:MGI:2681367|PMID:14576348
Biological Process	GO:0030011	maintenance of cell polarity	DST	IMP		Human	PMID:19403692
Biological Process	GO:0009611	response to wounding	DST	IDA		Human	PMID:19403692
Biological Process	GO:0008090	retrograde axonal transport	Dst	IMP		Mouse	MGI:MGI:3703204|PMID:17287360
Biological Process	GO:0008090	retrograde axonal transport	Dst	IMP	MGI:MGI:2429314	Mouse	PMID:14581450

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern