Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DUSP18
  • Mouse genes Dusp18
  • Rat genes Dusp18
  • Zfish genes zgc:153044
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dusp18

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016791	phosphatase activity	DUSP18	IDA		Human	PMID:24531476
Molecular Function	GO:0005515	protein binding	DUSP18	IPI	UniProtKB:P06213	Human	PMID:28065597
Molecular Function	GO:0005515	protein binding	DUSP18	IPI	UniProtKB:Q8WXH2	Human	PMID:32814053
Molecular Function	GO:0004725	protein tyrosine phosphatase activity	DUSP18	IDA		Human	PMID:12408986
Molecular Function	GO:0008138	protein tyrosine/serine/threonine phosphatase activity	DUSP18	IDA		Human	PMID:12591617
Cellular Component	GO:0005737	cytoplasm	DUSP18	IDA		Human	PMID:12408986
Cellular Component	GO:0005829	cytosol	Dusp18	IDA		Rat	PMID:18385140|RGD:7241011
Cellular Component	GO:0005758	mitochondrial intermembrane space	Dusp18	IDA		Rat	PMID:18385140|RGD:7241011
Cellular Component	GO:0005654	nucleoplasm	DUSP18	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DUSP18	IDA		Human	PMID:12408986
Biological Process	GO:0016311	dephosphorylation	DUSP18	IDA		Human	PMID:24531476
Biological Process	GO:0035970	peptidyl-threonine dephosphorylation	DUSP18	IDA		Human	PMID:12591617
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	DUSP18	IDA		Human	PMID:12408986
Biological Process	GO:0035335	peptidyl-tyrosine dephosphorylation	DUSP18	IDA		Human	PMID:12591617

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern