Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Dync1h1

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes DYNC1H1
- Mouse genes Dync1h1
- Rat genes Dync1h1
- Zfish genes dync1h1
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dync1h1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0051959	dynein light intermediate chain binding	DYNC1H1	IPI	UniProtKB:Q9Y6G9	Human	PMID:25272277
Molecular Function	GO:0051959	dynein light intermediate chain binding	Dync1h1	IPI	PR:Q8BVN8	Mouse	PMID:16496424
Molecular Function	GO:0008569	minus-end-directed microtubule motor activity	DYNC1H1	IDA		Human	PMID:21723285
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q9NRI5	Human	PMID:17043677
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:P42858	Human	PMID:17500595
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:P42858	Human	PMID:17548833
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:P49810	Human	PMID:21163940
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:O75381	Human	PMID:21525035
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q9BSW2-2	Human	PMID:31092558
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q9NRI5	Human	PMID:31413325
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:B2RAF7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:O00308	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:O15273	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:O60237-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:O60506-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:O60830	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:O95817	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:P09668	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:P19388	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:P20783-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:P24522	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:P26998	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:P32243-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:P48443	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:P49336-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:P61964	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q12797-6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q13144	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q14005-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q15759	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q5T0L3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q6DKI2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q6P4D5-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q7L1Q6-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q7L5A8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q86WV2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q8IU80-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q8IUR5-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q92886	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q96DX8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q96EF9	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q96EJ4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q96QH2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q99683	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q9BTE7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q9BXU0	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q9BXY8	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q9BY12-3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q9NP61	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q9NX94	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q9Y281	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q9Y6H3	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:Q9Y6W6	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	DYNC1H1	IPI	UniProtKB:O75381	Human	PMID:35044719
Molecular Function	GO:0005515	protein binding	Dync1h1	IPI	UniProtKB:Q921C5	Mouse	MGI:MGI:5507956\|PMID:22956769
Molecular Function	GO:0005515	protein binding	Dync1h1	IPI	UniProtKB:P07141	Mouse	MGI:MGI:3696626\|PMID:16267818
Molecular Function	GO:0005515	protein binding	Dync1h1	IPI	UniProtKB:B2GV74	Rat	PMID:14985359\|RGD:8553555
Molecular Function	GO:0005515	protein binding	Dync1h1	IPI	UniProtKB:P37285	Rat	PMID:14985359\|RGD:8553555
Molecular Function	GO:0003723	RNA binding	DYNC1H1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	DYNC1H1	HDA		Human	PMID:22681889
Cellular Component	GO:0030424	axon	Dync1h1	IDA		Rat	PMID:1387878\|RGD:13207347
Cellular Component	GO:0005813	centrosome	DYNC1H1	IDA		Human	PMID:21399614
Cellular Component	GO:0005737	cytoplasm	Dync1h1	IDA		Mouse	PMID:16496424
Cellular Component	GO:0005737	cytoplasm	Dync1h1	IDA		Rat	PMID:1387878\|RGD:13207347
Cellular Component	GO:0005737	cytoplasm	Dync1h1	IDA		Rat	PMID:8832411\|RGD:13207346
Cellular Component	GO:0005868	cytoplasmic dynein complex	DYNC1H1	IDA		Human	PMID:21723285
Cellular Component	GO:0005868	cytoplasmic dynein complex	DYNC1H1	IDA		Human	PMID:25272277
Cellular Component	GO:0030286	dynein complex	DYNC1H1	IPI		Human	PMID:24986880
Cellular Component	GO:0070062	extracellular exosome	DYNC1H1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	DYNC1H1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	DYNC1H1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	DYNC1H1	HDA		Human	PMID:21362503
Cellular Component	GO:0070062	extracellular exosome	DYNC1H1	HDA		Human	PMID:23533145
Cellular Component	GO:0030175	filopodium	Dync1h1	IDA		Mouse	PMID:16496424
Cellular Component	GO:0002177	manchette	Dync1h1	IDA		Rat	PMID:8006076\|RGD:13207350
Cellular Component	GO:0016020	membrane	DYNC1H1	HDA		Human	PMID:19946888
Cellular Component	GO:0005874	microtubule	DYNC1H1	IDA		Human	PMID:21525035
Cellular Component	GO:0043025	neuronal cell body	Dync1h1	IDA		Rat	PMID:1387878\|RGD:13207347
Cellular Component	GO:0005635	nuclear envelope	Dync1h1	IDA		Rat	PMID:8006076\|RGD:13207350
Biological Process	GO:0060219	camera-type eye photoreceptor cell differentiation	dync1h1	IMP	ZFIN:ZDB-GENO-100723-15	Zfish	PMID:20412557
Biological Process	GO:1905243	cellular response to 3,3',5-triiodo-L-thyronine	Dync1h1	IEP		Rat	PMID:8922673\|RGD:13207348
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Dync1h1	IEP		Rat	PMID:8922673\|RGD:13207348
Biological Process	GO:0022010	central nervous system myelination	dync1h1	IMP	ZFIN:ZDB-GENO-150504-4	Zfish	PMID:25488883
Biological Process	GO:0051293	establishment of spindle localization	DYNC1H1	IMP		Human	PMID:23027904
Biological Process	GO:0042552	myelination	dync1h1	IMP	ZFIN:ZDB-GENO-100723-16	Zfish	PMID:23167977
Biological Process	GO:0033962	P-body assembly	Dync1h1	IMP		Mouse	MGI:MGI:4397616\|PMID:19825938
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Dync1h1	IMP		Mouse	MGI:MGI:4944121\|PMID:20887786
Biological Process	GO:0032388	positive regulation of intracellular transport	DYNC1H1	IMP		Human	PMID:27462074
Biological Process	GO:1905832	positive regulation of spindle assembly	DYNC1H1	IMP		Human	PMID:27462074
Biological Process	GO:0050865	regulation of cell activation	dync1h1	IMP		Zfish	PMID:30779743
Biological Process	GO:0090235	regulation of metaphase plate congression	DYNC1H1	IMP		Human	PMID:27462074
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	dync1h1	IMP		Zfish	PMID:30779743
Biological Process	GO:0060236	regulation of mitotic spindle organization	DYNC1H1	IMP		Human	PMID:23027904
Biological Process	GO:0007286	spermatid development	Dync1h1	IEP		Rat	PMID:8006076\|RGD:13207350
Biological Process	GO:0034063	stress granule assembly	Dync1h1	IMP		Mouse	MGI:MGI:4397616\|PMID:19825938

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/17/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.