Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DYRK3
  • Mouse genes Dyrk3
  • Rat genes Dyrk3
  • Zfish genes dyrk3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dyrk3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	DYRK3	IDA		Human	PMID:10779429
Molecular Function	GO:0005524	ATP binding	Dyrk3	IDA		Mouse	MGI:MGI:3715063|PMID:12356771
Molecular Function	GO:0000287	magnesium ion binding	DYRK3	IDA		Human	PMID:10779429
Molecular Function	GO:0000287	magnesium ion binding	Dyrk3	IDA		Mouse	MGI:MGI:3715063|PMID:12356771
Molecular Function	GO:0005515	protein binding	Dyrk3	IPI	UniProtKB:Q923E4	Mouse	MGI:MGI:4838949|PMID:20167603
Molecular Function	GO:0004672	protein kinase activity	DYRK3	IDA		Human	PMID:10779429
Molecular Function	GO:0004672	protein kinase activity	Dyrk3	IDA		Mouse	MGI:MGI:3715063|PMID:12356771
Molecular Function	GO:0004674	protein serine/threonine kinase activity	DYRK3	IMP		Human	PMID:23415227
Molecular Function	GO:0004674	protein serine/threonine kinase activity	DYRK3	IDA		Human	PMID:29634919
Molecular Function	GO:0004674	protein serine/threonine kinase activity	DYRK3	IDA		Human	PMID:29973724
Molecular Function	GO:0004674	protein serine/threonine kinase activity	Dyrk3	IMP		Mouse	MGI:MGI:4838949|PMID:20167603
Cellular Component	GO:0005737	cytoplasm	DYRK3	IDA		Human	PMID:23415227
Cellular Component	GO:0010494	cytoplasmic stress granule	DYRK3	IDA		Human	PMID:23415227
Cellular Component	GO:0010494	cytoplasmic stress granule	DYRK3	IDA		Human	PMID:29973724
Cellular Component	GO:0005829	cytosol	DYRK3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	DYRK3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016607	nuclear speck	DYRK3	IDA		Human	PMID:29973724
Cellular Component	GO:0005654	nucleoplasm	DYRK3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	DYRK3	IDA		Human	PMID:10779429
Cellular Component	GO:0005634	nucleus	DYRK3	IDA		Human	PMID:20167603
Cellular Component	GO:0000242	pericentriolar material	DYRK3	IDA		Human	PMID:29973724
Biological Process	GO:0030218	erythrocyte differentiation	DYRK3	IDA		Human	PMID:10779429
Biological Process	GO:0030218	erythrocyte differentiation	Dyrk3	IDA		Mouse	MGI:MGI:3715071|PMID:16524748
Biological Process	GO:0055001	muscle cell development	dyrk3	IMP	ZFIN:ZDB-MRPHLNO-180627-1	Zfish	PMID:28695966
Biological Process	GO:0043066	negative regulation of apoptotic process	Dyrk3	IMP		Mouse	MGI:MGI:4838949|PMID:20167603
Biological Process	GO:0043518	negative regulation of DNA damage response, signal transduction by p53 class mediator	Dyrk3	IMP		Mouse	MGI:MGI:4838949|PMID:20167603
Biological Process	GO:0035063	nuclear speck organization	DYRK3	IDA		Human	PMID:29973724
Biological Process	GO:1903008	organelle disassembly	DYRK3	IDA		Human	PMID:29973724
Biological Process	GO:1902751	positive regulation of cell cycle G2/M phase transition	DYRK3	IDA		Human	PMID:29973724
Biological Process	GO:0006468	protein phosphorylation	DYRK3	IDA		Human	PMID:10779429
Biological Process	GO:0006468	protein phosphorylation	DYRK3	IDA		Human	PMID:29634919
Biological Process	GO:0006468	protein phosphorylation	DYRK3	IDA		Human	PMID:29973724
Biological Process	GO:0006468	protein phosphorylation	Dyrk3	IDA		Mouse	MGI:MGI:3715063|PMID:12356771
Biological Process	GO:0080135	regulation of cellular response to stress	DYRK3	IMP		Human	PMID:23415227
Biological Process	GO:1903432	regulation of TORC1 signaling	DYRK3	IMP		Human	PMID:23415227
Biological Process	GO:0035617	stress granule disassembly	DYRK3	IMP		Human	PMID:23415227
Biological Process	GO:0035617	stress granule disassembly	DYRK3	IDA		Human	PMID:29973724

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern