Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes DYSF
  • Mouse genes Dysf
  • Rat genes Dysf
  • Zfish genes dysf
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Dysf

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0043014	alpha-tubulin binding	Dysf	IPI	PR:P68368	Mouse	PMID:20405035
Molecular Function	GO:0043014	alpha-tubulin binding	Dysf	IDA		Mouse	PMID:22174839
Molecular Function	GO:0043014	alpha-tubulin binding	Dysf	IDA		Mouse	PMID:20405035
Molecular Function	GO:0043014	alpha-tubulin binding	Dysf	IPI	PR:P05213	Mouse	PMID:20405035
Molecular Function	GO:0005509	calcium ion binding	DYSF	IDA		Human	PMID:24239457
Molecular Function	GO:0005544	calcium-dependent phospholipid binding	DYSF	IMP		Human	PMID:11959863
Molecular Function	GO:0008017	microtubule binding	Dysf	IDA		Mouse	PMID:20405035
Molecular Function	GO:0005543	phospholipid binding	DYSF	IDA		Human	PMID:24239457
Molecular Function	GO:0005515	protein binding	DYSF	IPI	UniProtKB:Q09666	Human	PMID:17185750
Molecular Function	GO:0005515	protein binding	DYSF	IPI	UniProtKB:Q8IVF2	Human	PMID:17185750
Molecular Function	GO:0005515	protein binding	DYSF	IPI	UniProtKB:P20929	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	DYSF	IPI	UniProtKB:P52179	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	DYSF	IPI	UniProtKB:P54296	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	DYSF	IPI	UniProtKB:Q00872	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	DYSF	IPI	UniProtKB:Q13326	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	DYSF	IPI	UniProtKB:Q8WZ42	Human	PMID:23414517
Molecular Function	GO:0005515	protein binding	DYSF	IPI	UniProtKB:Q9UBN7	Human	PMID:24687993
Molecular Function	GO:0005515	protein binding	DYSF	IPI	UniProtKB:Q9Y4F9	Human	PMID:24687993
Molecular Function	GO:0005515	protein binding	Dysf	IPI	UniProtKB:Q80U16	Mouse	MGI:MGI:5607386|PMID:24687993
Molecular Function	GO:0005515	protein binding	Dysf	IPI	UniProtKB:Q09666	Mouse	MGI:MGI:5545998|PMID:17185750
Molecular Function	GO:0005515	protein binding	Dysf	IPI	PR:P07356	Mouse	PMID:14506282
Molecular Function	GO:0005515	protein binding	Dysf	IPI	MGI:MGI:1316648	Mouse	PMID:20405035
Molecular Function	GO:0005515	protein binding	Dysf	IPI	PR:Q64691	Mouse	PMID:20405035
Molecular Function	GO:0005515	protein binding	Dysf	IPI	PR:Q08481	Mouse	PMID:20724702
Molecular Function	GO:0005515	protein binding	Dysf	IPI	PR:P10107	Mouse	PMID:14506282
Molecular Function	GO:0005515	protein binding	Dysf	IPI	MGI:MGI:1316648	Mouse	PMID:19380584
Molecular Function	GO:0005515	protein binding	Dysf	IPI	PR:P51637	Mouse	PMID:19380584
Molecular Function	GO:0005515	protein binding	Dysf	IPI	PR:P10107	Mouse	PMID:20405035
Molecular Function	GO:0005515	protein binding	Dysf	IPI	PR:Q9Z2V5	Mouse	PMID:22174839
Molecular Function	GO:0005515	protein binding	Dysf	IPI	PR:Q9ES46	Mouse	PMID:20405035
Molecular Function	GO:0005515	protein binding	Dysf	IPI	PR:P51637	Mouse	PMID:20405035
Molecular Function	GO:0005515	protein binding	Dysf	IPI	PR:P07356	Mouse	PMID:20405035
Cellular Component	GO:0034451	centriolar satellite	DYSF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	Dysf	IDA		Mouse	PMID:22174839
Cellular Component	GO:0005737	cytoplasm	Dysf	IDA		Rat	PMID:17185750|RGD:8553518
Cellular Component	GO:0031410	cytoplasmic vesicle	Dysf	IDA		Mouse	MGI:MGI:2657049|PMID:12736685
Cellular Component	GO:0005769	early endosome	DYSF	IDA		Human	PMID:20595382
Cellular Component	GO:0030139	endocytic vesicle	DYSF	IDA		Human	PMID:20595382
Cellular Component	GO:0005768	endosome	DYSF	IDA		Human	PMID:20595382
Cellular Component	GO:0070062	extracellular exosome	DYSF	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	DYSF	HDA		Human	PMID:23533145
Cellular Component	GO:0005794	Golgi apparatus	Dysf	IDA		Mouse	PMID:20724702
Cellular Component	GO:0030027	lamellipodium	Dysf	IDA		Mouse	MGI:MGI:5447607|PMID:18325335
Cellular Component	GO:0005770	late endosome	DYSF	IDA		Human	PMID:20595382
Cellular Component	GO:0098857	membrane microdomain	Dysf	IDA		Mouse	PMID:20724702
Cellular Component	GO:0005874	microtubule	Dysf	IDA		Mouse	PMID:20405035
Cellular Component	GO:0005634	nucleus	Dysf	IDA		Mouse	PMID:20724702
Cellular Component	GO:0005886	plasma membrane	DYSF	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	DYSF	IDA		Human	PMID:20595382
Cellular Component	GO:0005886	plasma membrane	DYSF	IDA		Human	PMID:24239457
Cellular Component	GO:0005886	plasma membrane	Dysf	IDA		Mouse	PMID:20724702
Cellular Component	GO:0005886	plasma membrane	Dysf	IDA		Mouse	PMID:24784578
Cellular Component	GO:0005886	plasma membrane	Dysf	IDA		Mouse	PMID:22174839
Cellular Component	GO:0042383	sarcolemma	DYSF	IDA		Human	PMID:17185750
Cellular Component	GO:0042383	sarcolemma	Dysf	IDA		Mouse	MGI:MGI:2657049|PMID:12736685
Cellular Component	GO:0042383	sarcolemma	Dysf	IDA		Mouse	PMID:16371353
Cellular Component	GO:0042383	sarcolemma	Dysf	IDA		Mouse	PMID:14506282
Cellular Component	GO:0042383	sarcolemma	Dysf	IDA		Mouse	PMID:16319126
Cellular Component	GO:0042383	sarcolemma	Dysf	IDA		Mouse	PMID:24784578
Cellular Component	GO:0042383	sarcolemma	dysf	IDA		Zfish	PMID:22421042
Cellular Component	GO:0030315	T-tubule	DYSF	IDA		Human	PMID:17185750
Cellular Component	GO:0030315	T-tubule	Dysf	IDA		Mouse	PMID:24302765
Cellular Component	GO:0030315	T-tubule	Dysf	IDA		Mouse	PMID:24784578
Cellular Component	GO:0030315	T-tubule	Dysf	IDA		Mouse	PMID:16319126
Cellular Component	GO:0030315	T-tubule	dysf	IDA		Zfish	PMID:22421042
Biological Process	GO:0001525	angiogenesis	Dysf	IMP		Mouse	PMID:20724702
Biological Process	GO:0001525	angiogenesis	Dysf	IMP	MGI:MGI:3055139	Mouse	PMID:20724702
Biological Process	GO:0071470	cellular response to osmotic stress	Dysf	IMP	MGI:MGI:3055150	Mouse	PMID:24302765
Biological Process	GO:0001816	cytokine production	Dysf	IMP	MGI:MGI:1857883	Mouse	PMID:19286669
Biological Process	GO:0045444	fat cell differentiation	Dysf	IMP	MGI:MGI:3055150	Mouse	PMID:24685690
Biological Process	GO:0006071	glycerol metabolic process	Dysf	IMP	MGI:MGI:3055139	Mouse	PMID:24177035
Biological Process	GO:0006071	glycerol metabolic process	Dysf	IGI	MGI:MGI:1919192	Mouse	PMID:24177035
Biological Process	GO:0019915	lipid storage	Dysf	IMP	MGI:MGI:3055150	Mouse	PMID:24685690
Biological Process	GO:0002281	macrophage activation involved in immune response	DYSF	IMP		Human	PMID:18276788
Biological Process	GO:0002281	macrophage activation involved in immune response	Dysf	IMP	MGI:MGI:1857883	Mouse	PMID:18276788
Biological Process	GO:0002280	monocyte activation involved in immune response	DYSF	IMP		Human	PMID:18276788
Biological Process	GO:0002280	monocyte activation involved in immune response	Dysf	IMP	MGI:MGI:1857883	Mouse	PMID:18276788
Biological Process	GO:0055001	muscle cell development	Dysf	IMP	MGI:MGI:3055139	Mouse	PMID:24177035
Biological Process	GO:0055001	muscle cell development	Dysf	IMP	MGI:MGI:3055150	Mouse	PMID:24685690
Biological Process	GO:0055001	muscle cell development	Dysf	IGI	MGI:MGI:1919192	Mouse	PMID:24177035
Biological Process	GO:0048644	muscle organ morphogenesis	dysf	IMP	ZFIN:ZDB-MRPHLNO-111111-6	Zfish	PMID:21893049
Biological Process	GO:0010629	negative regulation of gene expression	Dysf	IMP	MGI:MGI:1857883	Mouse	PMID:18276788
Biological Process	GO:1901842	negative regulation of high voltage-gated calcium channel activity	Dysf	IMP	MGI:MGI:3055150	Mouse	PMID:24302765
Biological Process	GO:0050765	negative regulation of phagocytosis	DYSF	IMP		Human	PMID:18276788
Biological Process	GO:0050765	negative regulation of phagocytosis	Dysf	IMP	MGI:MGI:1857883	Mouse	PMID:18276788
Biological Process	GO:0032091	negative regulation of protein binding	Dysf	IMP		Mouse	PMID:22174839
Biological Process	GO:0042177	negative regulation of protein catabolic process	Dysf	IMP		Mouse	PMID:20724702
Biological Process	GO:1902915	negative regulation of protein polyubiquitination	Dysf	IMP		Mouse	PMID:20724702
Biological Process	GO:1904428	negative regulation of tubulin deacetylation	Dysf	IMP		Mouse	PMID:22174839
Biological Process	GO:0001778	plasma membrane repair	Dysf	IMP		Mouse	MGI:MGI:2657049|PMID:12736685
Biological Process	GO:0001778	plasma membrane repair	Dysf	IDA		Mouse	PMID:24784578
Biological Process	GO:0001778	plasma membrane repair	Dysf	IDA		Mouse	PMID:14506282
Biological Process	GO:0001778	plasma membrane repair	dysf	IMP		Zfish	PMID:27641898
Biological Process	GO:0001778	plasma membrane repair	dysf	IMP	ZFIN:ZDB-MRPHLNO-120404-2	Zfish	PMID:22421042
Biological Process	GO:0045785	positive regulation of cell adhesion	Dysf	IMP		Mouse	PMID:20724702
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	Dysf	IMP		Mouse	PMID:20724702
Biological Process	GO:0090023	positive regulation of neutrophil chemotaxis	Dysf	IMP	MGI:MGI:1857883	Mouse	PMID:19286669
Biological Process	GO:0030163	protein catabolic process	Dysf	IMP		Mouse	PMID:20724702
Biological Process	GO:0000209	protein polyubiquitination	Dysf	IMP		Mouse	PMID:20724702
Biological Process	GO:0090279	regulation of calcium ion import	Dysf	IMP	MGI:MGI:3055150	Mouse	PMID:24302765
Biological Process	GO:0007519	skeletal muscle tissue development	Dysf	IDA		Mouse	PMID:22174839
Biological Process	GO:0043403	skeletal muscle tissue regeneration	Dysf	IMP	MGI:MGI:1857883	Mouse	PMID:19286669
Biological Process	GO:0033292	T-tubule organization	Dysf	IGI	MGI:MGI:1919192	Mouse	PMID:24177035
Biological Process	GO:0033292	T-tubule organization	Dysf	IMP	MGI:MGI:3055150	Mouse	PMID:24302765
Biological Process	GO:0033292	T-tubule organization	dysf	IMP	ZFIN:ZDB-MRPHLNO-120404-2	Zfish	PMID:22421042
Biological Process	GO:0006906	vesicle fusion	Dysf	IMP		Mouse	MGI:MGI:2657049|PMID:12736685

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern