Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes E2F3
  • Mouse genes E2f3
  • Rat genes E2f3
  • Zfish genes e2f3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set E2f3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	E2F3	IDA		Human	PMID:15735762
Molecular Function	GO:0003677	DNA binding	E2f3	IDA		Mouse	PMID:11980909
Molecular Function	GO:0003677	DNA binding	E2f3	IDA		Mouse	PMID:15574595
Molecular Function	GO:0003677	DNA binding	E2f3	IDA		Mouse	PMID:15722552
Molecular Function	GO:0001216	DNA-binding transcription activator activity	E2F3	IDA		Human	PMID:17062573
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	E2F3	IDA		Human	PMID:7739537
Molecular Function	GO:0003700	DNA-binding transcription factor activity	E2f3	IDA		Mouse	PMID:11980909
Molecular Function	GO:0005515	protein binding	E2F3	IPI	UniProtKB:P06400	Human	PMID:10779361
Molecular Function	GO:0005515	protein binding	E2F3	IPI	UniProtKB:Q5H9I0	Human	PMID:17062573
Molecular Function	GO:0005515	protein binding	E2F3	IPI	UniProtKB:P06400	Human	PMID:17380128
Molecular Function	GO:0005515	protein binding	E2F3	IPI	UniProtKB:P61201	Human	PMID:17438371
Molecular Function	GO:0005515	protein binding	E2F3	IPI	UniProtKB:Q96JM7	Human	PMID:17517653
Molecular Function	GO:0005515	protein binding	E2F3	IPI	UniProtKB:P06400	Human	PMID:19249677
Molecular Function	GO:0005515	protein binding	E2F3	IPI	UniProtKB:P06400	Human	PMID:22157815
Molecular Function	GO:0005515	protein binding	E2F3	IPI	UniProtKB:Q96JM7	Human	PMID:22157815
Molecular Function	GO:0005515	protein binding	E2F3	IPI	UniProtKB:Q9NRZ9	Human	PMID:22157815
Molecular Function	GO:0005515	protein binding	E2F3	IPI	UniProtKB:P06400	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	E2f3	IPI	PR:Q08639	Mouse	PMID:15448153
Molecular Function	GO:0005515	protein binding	E2f3	IPI	PR:P25322	Mouse	PMID:11980909
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	E2F3	IDA		Human	PMID:7739537
Molecular Function	GO:0043565	sequence-specific DNA binding	E2F3	IDA		Human	PMID:23332764
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	E2F3	IDA		Human	PMID:28473536
Cellular Component	GO:0005634	nucleus	E2F3	IDA		Human	PMID:17062573
Cellular Component	GO:0090575	RNA polymerase II transcription regulator complex	E2F3	IDA		Human	PMID:7739537
Biological Process	GO:0000082	G1/S transition of mitotic cell cycle	E2F3	IDA		Human	PMID:17062573
Biological Process	GO:0070345	negative regulation of fat cell proliferation	E2f3	IMP		Mouse	MGI:MGI:4461077|PMID:20176812
Biological Process	GO:0008284	positive regulation of cell population proliferation	E2f3	IDA		Mouse	PMID:12893818
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	E2f3	IDA		Mouse	PMID:12893818
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	E2F3	IDA		Human	PMID:7739537
Biological Process	GO:1905461	positive regulation of vascular associated smooth muscle cell apoptotic process	E2F3	IMP		Human	PMID:22886504
Biological Process	GO:0006606	protein import into nucleus	E2F3	IDA		Human	PMID:17062573
Biological Process	GO:0006355	regulation of DNA-templated transcription	E2f3	IDA		Mouse	PMID:11980909

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern