Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse E2f7

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes E2F7
- Mouse genes E2f7
- Rat genes E2f7
- Zfish genes e2f7
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set E2f7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0000987	cis-regulatory region sequence-specific DNA binding	E2F7	IDA		Human	PMID:22903062
Molecular Function	GO:0003677	DNA binding	e2f7	IDA		Zfish	PMID:22903062
Molecular Function	GO:0003700	DNA-binding transcription factor activity	E2F7	IDA		Human	PMID:22802528
Molecular Function	GO:0003700	DNA-binding transcription factor activity	E2F7	IMP		Human	PMID:22903062
Molecular Function	GO:0003700	DNA-binding transcription factor activity	E2f7	IMP		Mouse	MGI:MGI:5319718\|PMID:22516201
Molecular Function	GO:0003700	DNA-binding transcription factor activity	E2f7	IMP		Mouse	MGI:MGI:5449497\|PMID:23064266
Molecular Function	GO:0003700	DNA-binding transcription factor activity	E2f7	IDA		Mouse	MGI:MGI:5448509\|PMID:22180533
Molecular Function	GO:0003700	DNA-binding transcription factor activity	E2f7	IDA		Mouse	PMID:12893818
Molecular Function	GO:0003700	DNA-binding transcription factor activity	e2f7	IMP		Zfish	PMID:22903062\|ZFIN:ZDB-PUB-120822-27
Molecular Function	GO:0001217	DNA-binding transcription repressor activity	E2f7	IDA		Mouse	MGI:MGI:5448509\|PMID:22180533
Molecular Function	GO:0001217	DNA-binding transcription repressor activity	E2f7	IMP		Mouse	MGI:MGI:5449497\|PMID:23064266
Molecular Function	GO:0001217	DNA-binding transcription repressor activity	E2f7	IMP		Mouse	MGI:MGI:5319718\|PMID:22516201
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	E2f7	IDA		Mouse	MGI:MGI:2678852\|PMID:12893818
Molecular Function	GO:0042802	identical protein binding	E2F7	IPI	UniProtKB:Q96AV8	Human	PMID:15133492
Molecular Function	GO:0005515	protein binding	E2F7	IPI	UniProtKB:A0AVK6	Human	PMID:18202719
Molecular Function	GO:0005515	protein binding	E2F7	IPI	UniProtKB:Q10571	Human	PMID:31839203
Molecular Function	GO:0005515	protein binding	E2f7	IPI	UniProtKB:Q16665	Mouse	MGI:MGI:5447251\|PMID:22903062
Molecular Function	GO:0005515	protein binding	e2f7	IPI	UniProtKB:Q16665	Zfish	PMID:22903062\|ZFIN:ZDB-PUB-120822-27
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	E2f7	IDA		Mouse	MGI:MGI:5448509\|PMID:22180533
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	E2f7	IDA		Mouse	MGI:MGI:2678852\|PMID:12893818
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	E2F7	IDA		Human	PMID:28473536
Cellular Component	GO:0016607	nuclear speck	E2F7	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	E2f7	IDA		Mouse	PMID:12893818
Biological Process	GO:0060718	chorionic trophoblast cell differentiation	E2f7	IMP		Mouse	MGI:MGI:5319718\|PMID:22516201
Biological Process	GO:0030330	DNA damage response, signal transduction by p53 class mediator	E2F7	IDA		Human	PMID:22802528
Biological Process	GO:0070365	hepatocyte differentiation	E2f7	IMP		Mouse	MGI:MGI:5449497\|PMID:23064266
Biological Process	GO:0001946	lymphangiogenesis	e2f7	IGI	ZFIN:ZDB-MRPHLNO-121116-1,ZFIN:ZDB-MRPHLNO-121116-2	Zfish	PMID:24069224
Biological Process	GO:0001946	lymphangiogenesis	e2f7	IGI	ZFIN:ZDB-MRPHLNO-090507-1,ZFIN:ZDB-MRPHLNO-121116-1,ZFIN:ZDB-MRPHLNO-121116-2	Zfish	PMID:24069224
Biological Process	GO:0001946	lymphangiogenesis	e2f7	IGI	ZFIN:ZDB-MRPHLNO-100205-5,ZFIN:ZDB-MRPHLNO-121116-1,ZFIN:ZDB-MRPHLNO-121116-2	Zfish	PMID:24069224
Biological Process	GO:0008045	motor neuron axon guidance	e2f7	IGI	ZFIN:ZDB-GENE-030519-2,ZFIN:ZDB-GENE-041111-260	Zfish	PMID:26681691
Biological Process	GO:0008045	motor neuron axon guidance	e2f7	IGI	ZFIN:ZDB-GENE-041111-260	Zfish	PMID:26681691
Biological Process	GO:0008285	negative regulation of cell population proliferation	E2F7	IMP		Human	PMID:22802528
Biological Process	GO:0008285	negative regulation of cell population proliferation	E2f7	IDA		Mouse	PMID:12893818
Biological Process	GO:0032466	negative regulation of cytokinesis	E2f7	IMP		Mouse	MGI:MGI:5449497\|PMID:23064266
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	e2f7	IGI	ZFIN:ZDB-GENE-041111-260	Zfish	PMID:26681691
Biological Process	GO:2000134	negative regulation of G1/S transition of mitotic cell cycle	E2f7	IDA		Mouse	MGI:MGI:5448509\|PMID:22180533
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	E2F7	IDA		Human	PMID:22802528
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	E2f7	IMP		Mouse	MGI:MGI:5449497\|PMID:23064266
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	E2f7	IDA		Mouse	MGI:MGI:2678852\|PMID:12893818
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	E2f7	IMP		Mouse	MGI:MGI:5319718\|PMID:22516201
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	E2f7	IDA		Mouse	MGI:MGI:5448509\|PMID:22180533
Biological Process	GO:0071930	negative regulation of transcription involved in G1/S transition of mitotic cell cycle	E2F7	IDA		Human	PMID:22802528
Biological Process	GO:0001890	placenta development	E2f7	IMP		Mouse	MGI:MGI:5319718\|PMID:22516201
Biological Process	GO:0032877	positive regulation of DNA endoreduplication	E2f7	IMP		Mouse	MGI:MGI:5449497\|PMID:23064266
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	E2F7	IMP		Human	PMID:22903062
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	e2f7	IMP		Zfish	PMID:22903062\|ZFIN:ZDB-PUB-120822-27
Biological Process	GO:0006355	regulation of DNA-templated transcription	E2f7	IDA		Mouse	PMID:12893818
Biological Process	GO:0002040	sprouting angiogenesis	E2F7	IMP		Human	PMID:22903062
Biological Process	GO:0002040	sprouting angiogenesis	E2f7	IMP		Mouse	MGI:MGI:5447251\|PMID:22903062
Biological Process	GO:0002040	sprouting angiogenesis	e2f7	IMP		Zfish	PMID:22903062\|ZFIN:ZDB-PUB-120822-27
Biological Process	GO:0002040	sprouting angiogenesis	e2f7	IGI	ZFIN:ZDB-MRPHLNO-100205-5,ZFIN:ZDB-MRPHLNO-121116-1,ZFIN:ZDB-MRPHLNO-121116-2	Zfish	PMID:24069224
Biological Process	GO:0002040	sprouting angiogenesis	e2f7	IGI	ZFIN:ZDB-MRPHLNO-050513-12,ZFIN:ZDB-MRPHLNO-121116-1,ZFIN:ZDB-MRPHLNO-121116-2	Zfish	PMID:22903062
Biological Process	GO:0002040	sprouting angiogenesis	e2f7	IGI	ZFIN:ZDB-MRPHLNO-121116-1,ZFIN:ZDB-MRPHLNO-121116-2	Zfish	PMID:24069224
Biological Process	GO:0002040	sprouting angiogenesis	e2f7	IGI	ZFIN:ZDB-MRPHLNO-121116-1,ZFIN:ZDB-MRPHLNO-121116-2	Zfish	PMID:22903062
Biological Process	GO:0002040	sprouting angiogenesis	e2f7	IGI	ZFIN:ZDB-MRPHLNO-090507-1,ZFIN:ZDB-MRPHLNO-121116-1,ZFIN:ZDB-MRPHLNO-121116-2	Zfish	PMID:24069224
Biological Process	GO:0060707	trophoblast giant cell differentiation	E2f7	IMP		Mouse	MGI:MGI:5449497\|PMID:23064266

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 10/15/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.