Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EAF1
  • Mouse genes Eaf1
  • Rat genes Eaf1
  • Zfish genes eaf1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eaf1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070016	armadillo repeat domain binding	eaf1	IDA		Zfish	PMID:23364330
Molecular Function	GO:0008013	beta-catenin binding	eaf1	IPI	ZFIN:ZDB-GENE-040426-2575	Zfish	PMID:23364330
Molecular Function	GO:0008013	beta-catenin binding	eaf1	IPI	ZFIN:ZDB-GENE-980526-362	Zfish	PMID:23364330
Molecular Function	GO:0003682	chromatin binding	eaf1	IDA		Zfish	PMID:24445282
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:P61289	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q9NSC5	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:O00472	Human	PMID:21729782
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:O95402	Human	PMID:21729782
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q9HB65	Human	PMID:21729782
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:O00560	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:O43829	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:P61289	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q08117	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q12800	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q8N7W2-2	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q8TAP6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q8TD10	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q9NSC5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:P61289	Human	PMID:27107012
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:O00472	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q9HB65	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:A6NEM1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:O00472	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:O75031	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:O95125	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:O95379	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:O95995	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:P04279-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:P19237	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:P26367	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:P32780	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:P37108	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:P52747	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:P61289	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q14145	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q15560	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q4LE39-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q5JQS6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q5SQQ9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q6PI77	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q6ZNG0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q7L190	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q86T90	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q86W67	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q8IY57-5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q8N488	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q8N8X9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q8NCX0-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q8NHQ1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q8TAE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q8TE85-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q92759	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q96CW1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q96MF2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q9BVG3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q9H147	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q9HB65	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q9NSC5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q9NWS0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EAF1	IPI	UniProtKB:Q08117	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	eaf1	IPI	ZFIN:ZDB-GENE-990415-270	Zfish	PMID:28887217
Molecular Function	GO:0005515	protein binding	eaf1	IPI	ZFIN:ZDB-GENE-000616-15	Zfish	PMID:28887217
Molecular Function	GO:0005515	protein binding	eaf1	IPI	ZFIN:ZDB-GENE-990603-8	Zfish	PMID:28887217
Molecular Function	GO:0005515	protein binding	eaf1	IPI	ZFIN:ZDB-GENE-990603-7	Zfish	PMID:28887217
Molecular Function	GO:0005515	protein binding	eaf1	IPI	ZFIN:ZDB-GENE-000509-3	Zfish	PMID:28887217
Molecular Function	GO:0005515	protein binding	eaf1	IPI	ZFIN:ZDB-GENE-030131-7859	Zfish	PMID:23364330
Molecular Function	GO:0003714	transcription corepressor activity	eaf1	IMP	ZFIN:ZDB-MRPHLNO-090820-4	Zfish	PMID:28887217
Molecular Function	GO:0003714	transcription corepressor activity	eaf1	IDA		Zfish	PMID:28887217
Molecular Function	GO:0003714	transcription corepressor activity	eaf1	IPI	ZFIN:ZDB-GENE-990415-270	Zfish	PMID:28887217
Molecular Function	GO:0003711	transcription elongation factor activity	EAF1	IMP		Human	PMID:32087315
Cellular Component	GO:0045171	intercellular bridge	EAF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	EAF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016604	nuclear body	EAF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	EAF1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0008023	transcription elongation factor complex	EAF1	IDA		Human	PMID:22195968
Biological Process	GO:0042074	cell migration involved in gastrulation	eaf1	IGI	ZFIN:ZDB-MRPHLNO-090820-4,ZFIN:ZDB-MRPHLNO-090820-6	Zfish	PMID:19380582
Biological Process	GO:0060028	convergent extension involved in axis elongation	eaf1	IMP	ZFIN:ZDB-MRPHLNO-090820-4	Zfish	PMID:19380582
Biological Process	GO:0060029	convergent extension involved in organogenesis	eaf1	IGI	ZFIN:ZDB-MRPHLNO-090820-4,ZFIN:ZDB-MRPHLNO-090820-6	Zfish	PMID:19380582
Biological Process	GO:0060216	definitive hemopoiesis	eaf1	IMP	ZFIN:ZDB-MRPHLNO-130501-8	Zfish	PMID:24445282
Biological Process	GO:0007507	heart development	eaf1	IGI	ZFIN:ZDB-MRPHLNO-090820-4,ZFIN:ZDB-MRPHLNO-090820-6	Zfish	PMID:19380582
Biological Process	GO:0014812	muscle cell migration	eaf1	IGI	ZFIN:ZDB-MRPHLNO-090820-4,ZFIN:ZDB-MRPHLNO-090820-6	Zfish	PMID:19380582
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	eaf1	IDA		Zfish	PMID:24445282
Biological Process	GO:0031016	pancreas development	eaf1	IGI	ZFIN:ZDB-MRPHLNO-090820-4,ZFIN:ZDB-MRPHLNO-090820-6	Zfish	PMID:19380582
Biological Process	GO:0060215	primitive hemopoiesis	eaf1	IGI	ZFIN:ZDB-GENE-990708-6	Zfish	PMID:24445282
Biological Process	GO:0060215	primitive hemopoiesis	eaf1	IMP	ZFIN:ZDB-MRPHLNO-130501-8	Zfish	PMID:24445282
Biological Process	GO:0034243	regulation of transcription elongation by RNA polymerase II	EAF1	IMP		Human	PMID:32087315
Biological Process	GO:0030111	regulation of Wnt signaling pathway	eaf1	IGI	ZFIN:ZDB-MRPHLNO-090820-4,ZFIN:ZDB-MRPHLNO-090820-6	Zfish	PMID:19380582
Biological Process	GO:0060799	transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification	eaf1	IMP	ZFIN:ZDB-MRPHLNO-090820-4	Zfish	PMID:28887217
Biological Process	GO:0060799	transforming growth factor beta receptor signaling pathway involved in endodermal cell fate specification	eaf1	IMP		Zfish	PMID:28887217
Biological Process	GO:0060798	transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification	eaf1	IMP		Zfish	PMID:28887217
Biological Process	GO:0060798	transforming growth factor beta receptor signaling pathway involved in mesodermal cell fate specification	eaf1	IMP	ZFIN:ZDB-MRPHLNO-090820-4	Zfish	PMID:28887217

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern