Comparative GO Graph (mouse, human, rat)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes RNASE2,RNASE3
  • Mouse genes Ear2
  • Rat genes Ear1,Rnase2
  • Zfish genes
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ear2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001530	lipopolysaccharide binding	RNASE3	IDA		Human	PMID:23992292
Molecular Function	GO:0005515	protein binding	RNASE2	IPI	UniProtKB:Q15700	Human	PMID:32296183
Molecular Function	GO:0004540	RNA nuclease activity	RNASE2	IDA		Human	PMID:9826755
Cellular Component	GO:0070062	extracellular exosome	RNASE2	HDA		Human	PMID:23533145
Cellular Component	GO:0005615	extracellular space	RNASE3	IDA		Human	PMID:12860195
Biological Process	GO:0019731	antibacterial humoral response	RNASE3	IDA		Human	PMID:12860195
Biological Process	GO:0061844	antimicrobial humoral immune response mediated by antimicrobial peptide	RNASE3	IDA		Human	PMID:12860195
Biological Process	GO:0006935	chemotaxis	RNASE2	IDA		Human	PMID:12855582
Biological Process	GO:0006935	chemotaxis	Ear2	IDA		Mouse	MGI:MGI:3687893|PMID:12855582
Biological Process	GO:0050829	defense response to Gram-negative bacterium	RNASE3	IDA		Human	PMID:23992292
Biological Process	GO:0050830	defense response to Gram-positive bacterium	RNASE3	IDA		Human	PMID:12860195
Biological Process	GO:0050830	defense response to Gram-positive bacterium	RNASE3	IDA		Human	PMID:23992292
Biological Process	GO:0051607	defense response to virus	RNASE2	IDA		Human	PMID:9826755
Biological Process	GO:0043152	induction of bacterial agglutination	RNASE3	IDA		Human	PMID:23992292
Biological Process	GO:0045087	innate immune response	RNASE3	IDA		Human	PMID:23992292
Biological Process	GO:0002227	innate immune response in mucosa	RNASE3	IDA		Human	PMID:12860195
Biological Process	GO:0090501	RNA phosphodiester bond hydrolysis	RNASE2	IDA		Human	PMID:9826755

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern