Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EBF2
  • Mouse genes Ebf2
  • Rat genes Ebf2
  • Zfish genes ebf2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ebf2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Ebf2	IDA		Mouse	PMID:23499423
Molecular Function	GO:0003677	DNA binding	Ebf2	IDA		Mouse	PMID:9211912
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Ebf2	IDA		Mouse	MGI:MGI:2384470|PMID:12139918
Molecular Function	GO:0005515	protein binding	EBF2	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EBF2	IPI	UniProtKB:Q13077	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EBF2	IPI	UniProtKB:Q9H4W6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ebf2	IPI	UniProtKB:Q15475	Mouse	MGI:MGI:5812817|PMID:27923061
Molecular Function	GO:0005515	protein binding	Ebf2	IPI	PR:Q8K4J2	Mouse	PMID:12139918
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Ebf2	IDA		Mouse	MGI:MGI:2384470|PMID:12139918
Biological Process	GO:0060612	adipose tissue development	Ebf2	IMP	MGI:MGI:3037977	Mouse	PMID:23499423
Biological Process	GO:0050873	brown fat cell differentiation	Ebf2	IDA		Mouse	PMID:23499423
Biological Process	GO:0001709	cell fate determination	Ebf2	IDA		Mouse	PMID:23499423
Biological Process	GO:0035563	positive regulation of chromatin binding	Ebf2	IDA		Mouse	PMID:23499423
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Ebf2	IMP		Mouse	MGI:MGI:6101086|PMID:26844207
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Ebf2	IDA		Mouse	PMID:12139918
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ebf2	IDA		Mouse	MGI:MGI:2384470|PMID:12139918
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ebf2	IGI	MGI:MGI:97747	Mouse	PMID:23499423
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Ebf2	IGI	MGI:MGI:98214	Mouse	PMID:23499423

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern