Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ECM1
  • Mouse genes Ecm1
  • Rat genes Ecm1
  • Zfish genes ecm1a,ecm1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ecm1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005134	interleukin-2 receptor binding	Ecm1	IPI	PR:P01590	Mouse	PMID:21217760
Molecular Function	GO:0002020	protease binding	ECM1	IPI	UniProtKB:P14780	Human	PMID:16512877
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:P98160	Human	PMID:12604605
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q12805	Human	PMID:19275936
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q13751	Human	PMID:19275936
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:O15162	Human	PMID:20870722
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:O14910	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:O43559	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:O75344	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:O75603	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:O75934	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:O95872	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:P09234	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:P16144-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:P28799	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:P31273	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:P31323	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:P48023	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:P61968	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q08043	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q13064	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q2WGJ6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q5TA79	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q6L8H2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q86UW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q96EQ0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q96NU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q9BYQ3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q9H0I2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q9NQ94	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q9NX04	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q9UMX0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECM1	IPI	UniProtKB:Q9Y223-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ecm1	IPI	PR:Q9R0G6	Mouse	PMID:20138147
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ECM1	IDA		Human	PMID:20870722
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ECM1	HDA		Human	PMID:27068509
Cellular Component	GO:0062023	collagen-containing extracellular matrix	ECM1	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Ecm1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Ecm1	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0070062	extracellular exosome	ECM1	HDA		Human	PMID:19199708
Cellular Component	GO:0005615	extracellular space	Ecm1	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Cellular Component	GO:0005615	extracellular space	Ecm1	IDA		Mouse	PMID:7608209
Cellular Component	GO:0005615	extracellular space	Ecm1	IDA		Mouse	PMID:21217760
Biological Process	GO:0002063	chondrocyte development	Ecm1	IMP		Mouse	PMID:20138147
Biological Process	GO:0003416	endochondral bone growth	Ecm1	IMP		Mouse	PMID:20138147
Biological Process	GO:0006954	inflammatory response	Ecm1	IMP	MGI:MGI:4940879	Mouse	PMID:21217760
Biological Process	GO:0030502	negative regulation of bone mineralization	ECM1	IDA		Human	PMID:11165938
Biological Process	GO:0001960	negative regulation of cytokine-mediated signaling pathway	Ecm1	IDA		Mouse	PMID:21217760
Biological Process	GO:0010466	negative regulation of peptidase activity	ECM1	IDA		Human	PMID:16512877
Biological Process	GO:0045766	positive regulation of angiogenesis	ECM1	IDA		Human	PMID:11292659
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	ECM1	IDA		Human	PMID:11292659
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	ECM1	HMP		Human	PMID:12761501
Biological Process	GO:0030500	regulation of bone mineralization	Ecm1	IMP		Mouse	PMID:20138147
Biological Process	GO:2000404	regulation of T cell migration	Ecm1	IMP	MGI:MGI:4940879	Mouse	PMID:21217760
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Ecm1	IMP	MGI:MGI:4940879	Mouse	PMID:21217760
Biological Process	GO:0002828	regulation of type 2 immune response	Ecm1	IMP	MGI:MGI:4940879	Mouse	PMID:21217760

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern