Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ECSIT
  • Mouse genes Ecsit
  • Rat genes Ecsit
  • Zfish genes ecsit
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ecsit

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Ecsit	IDA		Mouse	PMID:14633973
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Ecsit	IDA		Mouse	PMID:14633973
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:Q9Y375	Human	PMID:17344420
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:Q9H845	Human	PMID:20816094
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:P02649	Human	PMID:21163940
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:P49768	Human	PMID:21163940
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:P49810	Human	PMID:21163940
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:Q9Y285	Human	PMID:21163940
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:A2RTX5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:O15479	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:P55040	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:Q13064	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:Q13515	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:Q86UW9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:Q96PN8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:Q9NX04	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:Q9UBU9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:Q9UI47-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:P03891	Human	PMID:32320651
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:Q96B77,UniProtKB:Q9GZY4,UniProtKB:Q9H845,UniProtKB:Q9Y375	Human	PMID:32320651
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:Q96B77,UniProtKB:Q9H845,UniProtKB:Q9Y375	Human	PMID:32320651
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:Q8IUX1,UniProtKB:Q9BUB7,UniProtKB:Q9H845,UniProtKB:Q9Y375	Human	PMID:33753518
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:Q9BUB7,UniProtKB:Q9H845,UniProtKB:Q9Y375	Human	PMID:33753518
Molecular Function	GO:0005515	protein binding	ECSIT	IPI	UniProtKB:Q9H845,UniProtKB:Q9NWH2,UniProtKB:Q9Y375	Human	PMID:33753518
Molecular Function	GO:0005515	protein binding	Ecsit	IPI	UniProtKB:P70196|UniProtKB:Q9Y4K3	Mouse	MGI:MGI:1344119|PMID:10465784
Molecular Function	GO:0005515	protein binding	Ecsit	IPI	UniProtKB:P70196	Mouse	MGI:MGI:5006867|PMID:21525932
Molecular Function	GO:0005515	protein binding	Ecsit	IPI	UniProtKB:P70196	Mouse	MGI:MGI:3688344|PMID:15102471
Molecular Function	GO:0005515	protein binding	Ecsit	IPI	PR:Q922Y2	Mouse	PMID:22588174
Cellular Component	GO:0005737	cytoplasm	ECSIT	IDA		Human	PMID:17344420
Cellular Component	GO:0005829	cytosol	ECSIT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005739	mitochondrion	ECSIT	IDA		Human	PMID:17344420
Cellular Component	GO:0005739	mitochondrion	Ecsit	HDA		Mouse	PMID:18614015
Cellular Component	GO:0005739	mitochondrion	Ecsit	IDA		Mouse	PMID:22588174
Cellular Component	GO:0005654	nucleoplasm	ECSIT	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ECSIT	IDA		Human	PMID:17344420
Cellular Component	GO:0005667	transcription regulator complex	Ecsit	IDA		Mouse	PMID:14633973
Biological Process	GO:0030509	BMP signaling pathway	Ecsit	IDA		Mouse	PMID:14633973
Biological Process	GO:0001707	mesoderm formation	Ecsit	IMP	MGI:MGI:2683025	Mouse	PMID:14633973
Biological Process	GO:0051341	regulation of oxidoreductase activity	ECSIT	IDA		Human	PMID:17344420
Biological Process	GO:0061635	regulation of protein complex stability	ECSIT	IDA		Human	PMID:17344420
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Ecsit	IDA		Mouse	PMID:14633973
Biological Process	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	Ecsit	IDA		Mouse	PMID:10465784
Biological Process	GO:0007178	transmembrane receptor protein serine/threonine kinase signaling pathway	Ecsit	IPI	PR:P70196	Mouse	PMID:10465784

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern