Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EDA
  • Mouse genes Eda
  • Rat genes Eda
  • Zfish genes eda
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eda

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q9HAV5	Human	PMID:11039935
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q9UNE0	Human	PMID:11039935
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q8VHX2	Human	PMID:11780064
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P26678	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P21145	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P26678	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P27449	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P49447	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P54852	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q6FHL7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q6P499	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q8TBU1	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q96F15	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q96IW7	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q9NRP0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q9UPQ8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P26678	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:O95214	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P21145	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P26678	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P27449	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P54852	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q6P499	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q96IW7	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:O95214	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P21145	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P26678	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P49447	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P54849	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P54852	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:P56557	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q01453	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q4LDR2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q5J8X5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q69YG0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q6P499	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q96F15	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q96IW7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q9H2L4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q9NVC3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q9UBY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EDA	IPI	UniProtKB:Q9UPQ8	Human	PMID:32296183
Molecular Function	GO:0005102	signaling receptor binding	EDA	IDA		Human	PMID:11039935
Cellular Component	GO:0045177	apical part of cell	Eda	IDA		Mouse	PMID:12629675
Cellular Component	GO:0005789	endoplasmic reticulum membrane	Eda	IDA		Mouse	PMID:10534613
Cellular Component	GO:0043231	intracellular membrane-bounded organelle	EDA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005811	lipid droplet	EDA	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Eda	IDA		Mouse	PMID:10534613
Biological Process	GO:0060348	bone development	eda	IMP	ZFIN:ZDB-GENO-090324-10	Zfish	PMID:18833299
Biological Process	GO:0060070	canonical Wnt signaling pathway	Eda	IMP	MGI:MGI:1856197	Mouse	PMID:19619491
Biological Process	GO:0007160	cell-matrix adhesion	Eda	IDA		Mouse	PMID:10534613
Biological Process	GO:0010467	gene expression	Eda	IMP	MGI:MGI:1856202	Mouse	PMID:17673451
Biological Process	GO:0001942	hair follicle development	Eda	IMP	MGI:MGI:1856197	Mouse	PMID:18689798
Biological Process	GO:0001942	hair follicle development	Eda	IGI	MGI:MGI:1352474	Mouse	PMID:18689798
Biological Process	GO:0001942	hair follicle development	Eda	IMP	MGI:MGI:1856197	Mouse	PMID:544312
Biological Process	GO:0060789	hair follicle placode formation	Eda	IGI	MGI:MGI:88276	Mouse	PMID:19619491
Biological Process	GO:0042476	odontogenesis	eda	IMP	ZFIN:ZDB-GENO-140820-8	Zfish	PMID:24821783
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	EDA	IMP		Human	PMID:27144394
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Eda	IMP	MGI:MGI:1856197	Mouse	PMID:10610025
Biological Process	GO:0042475	odontogenesis of dentin-containing tooth	Eda	IMP	MGI:MGI:1856197	Mouse	PMID:5893447
Biological Process	GO:0043473	pigmentation	Eda	IMP	MGI:MGI:1858152	Mouse	MGI:MGI:65389
Biological Process	GO:0043473	pigmentation	Eda	IMP	MGI:MGI:1856197	Mouse	PMID:4561716
Biological Process	GO:0090263	positive regulation of canonical Wnt signaling pathway	Eda	IMP	MGI:MGI:1856197	Mouse	PMID:19619491
Biological Process	GO:0010628	positive regulation of gene expression	Eda	IDA		Mouse	PMID:18508042
Biological Process	GO:0043123	positive regulation of I-kappaB kinase/NF-kappaB signaling	Eda	IMP	MGI:MGI:1856197	Mouse	PMID:18689798
Biological Process	GO:0051092	positive regulation of NF-kappaB transcription factor activity	EDA	IDA		Human	PMID:11039935
Biological Process	GO:1901224	positive regulation of NIK/NF-kappaB signaling	Eda	IDA		Mouse	PMID:12629675
Biological Process	GO:0060662	salivary gland cavitation	Eda	IDA		Mouse	PMID:12629675
Biological Process	GO:0043588	skin development	Eda	IMP	MGI:MGI:1856202	Mouse	PMID:17673451
Biological Process	GO:0061153	trachea gland development	Eda	IMP	MGI:MGI:1856197	Mouse	PMID:15973734

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern