Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EEA1
  • Mouse genes Eea1
  • Rat genes Eea1
  • Zfish genes eea1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eea1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005545	1-phosphatidylinositol binding	EEA1	IDA		Human	PMID:11256955
Molecular Function	GO:0030742	GTP-dependent protein binding	EEA1	IDA		Human	PMID:10491193
Molecular Function	GO:0005515	protein binding	EEA1	IPI	UniProtKB:P20339	Human	PMID:10491193
Molecular Function	GO:0005515	protein binding	EEA1	IPI	UniProtKB:P61020	Human	PMID:10491193
Molecular Function	GO:0005515	protein binding	EEA1	IPI	UniProtKB:Q63635	Human	PMID:10506127
Molecular Function	GO:0005515	protein binding	EEA1	IPI	UniProtKB:P20339	Human	PMID:11870209
Molecular Function	GO:0005515	protein binding	EEA1	IPI	UniProtKB:Q9UL26	Human	PMID:11870209
Molecular Function	GO:0005515	protein binding	EEA1	IPI	UniProtKB:Q7Z3T8	Human	PMID:14613930
Molecular Function	GO:0005515	protein binding	EEA1	IPI	UniProtKB:P04626	Human	PMID:16314522
Molecular Function	GO:0005515	protein binding	EEA1	IPI	UniProtKB:P20339	Human	PMID:16902405
Molecular Function	GO:0005515	protein binding	EEA1	IPI	UniProtKB:Q5K651	Human	PMID:24029230
Molecular Function	GO:0005515	protein binding	EEA1	IPI	UniProtKB:Q69Z37	Human	PMID:24029230
Molecular Function	GO:0005515	protein binding	EEA1	IPI	UniProtKB:Q8IVG5	Human	PMID:24029230
Molecular Function	GO:0005515	protein binding	EEA1	IPI	UniProtKB:P51148	Human	PMID:25114243
Molecular Function	GO:0005515	protein binding	EEA1	IPI	UniProtKB:P51148	Human	PMID:25266290
Molecular Function	GO:0005515	protein binding	EEA1	IPI	UniProtKB:Q7Z3T8	Human	PMID:29568061
Molecular Function	GO:0005515	protein binding	EEA1	IPI	UniProtKB:P20339	Human	PMID:9697774
Molecular Function	GO:0005515	protein binding	Eea1	IPI	PR:P35278	Mouse	PMID:20534488
Molecular Function	GO:0005515	protein binding	Eea1	IPI	PR:Q9CQD1	Mouse	PMID:20534488
Molecular Function	GO:0005515	protein binding	Eea1	IPI	RGD:1304859	Rat	PMID:18768694|RGD:13504749
Molecular Function	GO:0042803	protein homodimerization activity	EEA1	IDA		Human	PMID:11741531
Cellular Component	GO:0044308	axonal spine	Eea1	IDA		Mouse	PMID:23303939
Cellular Component	GO:0031410	cytoplasmic vesicle	Eea1	IDA		Mouse	PMID:23553667
Cellular Component	GO:0005829	cytosol	EEA1	IDA		Human	PMID:7768953
Cellular Component	GO:0005769	early endosome	EEA1	IDA		Human	PMID:11741531
Cellular Component	GO:0005769	early endosome	EEA1	IDA		Human	PMID:12536145
Cellular Component	GO:0005769	early endosome	EEA1	IDA		Human	PMID:15229288
Cellular Component	GO:0005769	early endosome	EEA1	IDA		Human	PMID:15792797
Cellular Component	GO:0005769	early endosome	EEA1	IDA		Human	PMID:15880641
Cellular Component	GO:0005769	early endosome	EEA1	IDA		Human	PMID:16542649
Cellular Component	GO:0005769	early endosome	EEA1	IDA		Human	PMID:18388320
Cellular Component	GO:0005769	early endosome	EEA1	IDA		Human	PMID:18767904
Cellular Component	GO:0005769	early endosome	EEA1	IDA		Human	PMID:19535332
Cellular Component	GO:0005769	early endosome	EEA1	IDA		Human	PMID:22719997
Cellular Component	GO:0005769	early endosome	EEA1	IDA		Human	PMID:25327288
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:21502359
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:17003038
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:23926254
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:24334765
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:24029230
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:17620357
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:20943658
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:15588329
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:26965651
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:15975910
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:16204232
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:23918928
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:18838382
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:14668490
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:24760869
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:15078902
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:12746448
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:17765678
Cellular Component	GO:0005769	early endosome	Eea1	IDA		Mouse	PMID:17716972
Cellular Component	GO:0005768	endosome	Eea1	IDA		Mouse	PMID:24239381
Cellular Component	GO:0005768	endosome	Eea1	IDA		Mouse	PMID:14718562
Cellular Component	GO:0005768	endosome	Eea1	IDA		Mouse	PMID:12890772
Cellular Component	GO:0005768	endosome	Eea1	IDA		Mouse	PMID:16923123
Cellular Component	GO:0005768	endosome	Eea1	IDA		Mouse	PMID:26582200
Cellular Component	GO:0070062	extracellular exosome	EEA1	HDA		Human	PMID:19056867
Cellular Component	GO:0019897	extrinsic component of plasma membrane	EEA1	IDA		Human	PMID:7768953
Cellular Component	GO:0098978	glutamatergic synapse	Eea1	IPI		Mouse	PMID:17113235
Cellular Component	GO:0098978	glutamatergic synapse	Eea1	IDA		Mouse	PMID:17113235
Cellular Component	GO:0016020	membrane	Eea1	IDA		Rat	PMID:20956289|RGD:152985549
Cellular Component	GO:0098794	postsynapse	Eea1	IDA		Mouse	PMID:17113235
Cellular Component	GO:0098794	postsynapse	Eea1	IPI		Mouse	PMID:17113235
Cellular Component	GO:0055037	recycling endosome	Eea1	IDA		Rat	PMID:10468577|RGD:4892345
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Eea1	IPI		Mouse	PMID:17113235
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Eea1	IDA		Mouse	PMID:17113235
Cellular Component	GO:0005969	serine-pyruvate aminotransferase complex	Eea1	IDA		Mouse	PMID:16399794
Biological Process	GO:0099565	chemical synaptic transmission, postsynaptic	Eea1	IPI		Mouse	PMID:17113235
Biological Process	GO:0099565	chemical synaptic transmission, postsynaptic	Eea1	IDA		Mouse	PMID:17113235
Biological Process	GO:0006897	endocytosis	EEA1	IMP		Human	PMID:21081650
Biological Process	GO:0044788	modulation by host of viral process	EEA1	IMP		Human	PMID:19376974
Biological Process	GO:0006906	vesicle fusion	EEA1	IMP		Human	PMID:9697774

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern