Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EED
  • Mouse genes Eed
  • Rat genes Eed
  • Zfish genes eed
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eed

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Eed	IDA		Mouse	PMID:16687444
Molecular Function	GO:0003682	chromatin binding	Eed	IDA		Mouse	PMID:24105743
Molecular Function	GO:0003682	chromatin binding	Eed	IDA		Rat	PMID:23354331|RGD:9588305
Molecular Function	GO:0008047	enzyme activator activity	EED	IMP		Human	PMID:28229514
Molecular Function	GO:0042054	histone methyltransferase activity	EED	IDA		Human	PMID:15385962
Molecular Function	GO:0042802	identical protein binding	EED	IPI	UniProtKB:O75530	Human	PMID:11124122
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:P26358	Human	PMID:16357870
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q9UBC3	Human	PMID:16357870
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q9Y6K1	Human	PMID:16357870
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q16531	Human	PMID:17041588
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15156	Human	PMID:17560333
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15022	Human	PMID:20075857
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q92833-1	Human	PMID:20075857
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:P63244	Human	PMID:20080539
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q9JJY3	Human	PMID:20080539
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q9NY59	Human	PMID:20080539
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q92800	Human	PMID:20211142
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15022	Human	PMID:20543829
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15022	Human	PMID:21078963
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q9Y232	Human	PMID:22009739
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:P26358	Human	PMID:22094255
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15910	Human	PMID:22094255
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q9UBC3	Human	PMID:22094255
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15022	Human	PMID:22439931
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15910	Human	PMID:22439931
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15910	Human	PMID:22897849
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q8IXJ9	Human	PMID:22897849
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q16531	Human	PMID:23238014
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15022	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15910	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q92800	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15022	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15910	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:P49368	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15022	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15910	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q92800	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15910	Human	PMID:28229514
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:O43189	Human	PMID:29628311
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:P49368	Human	PMID:30021884
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15910	Human	PMID:34591612
Molecular Function	GO:0005515	protein binding	EED	IPI	UniProtKB:Q15022	Human	PMID:35016035
Molecular Function	GO:0005515	protein binding	Eed	IPI	UniProtKB:Q62315	Mouse	MGI:MGI:4441020|PMID:20075857
Molecular Function	GO:0005515	protein binding	Eed	IPI	UniProtKB:Q7TNS8	Mouse	MGI:MGI:5507920|PMID:23180766
Molecular Function	GO:0005515	protein binding	Eed	IPI	UniProtKB:Q61188|UniProtKB:Q62315	Mouse	MGI:MGI:4436818|PMID:20064376
Molecular Function	GO:0005515	protein binding	Eed	IPI	UniProtKB:Q02395	Mouse	MGI:MGI:4436818|PMID:20064376
Molecular Function	GO:0005515	protein binding	Eed	IPI	UniProtKB:Q61188	Mouse	MGI:MGI:5300666|PMID:22094255
Molecular Function	GO:0005515	protein binding	Eed	IPI	UniProtKB:Q61188|UniProtKB:Q62315	Mouse	MGI:MGI:4431292|PMID:20064375
Molecular Function	GO:0005515	protein binding	Eed	IPI	UniProtKB:Q61188-1	Mouse	MGI:MGI:4441020|PMID:20075857
Molecular Function	GO:0005515	protein binding	Eed	IPI	UniProtKB:Q61188	Mouse	MGI:MGI:5508304|PMID:9742080
Molecular Function	GO:0005515	protein binding	Eed	IPI	UniProtKB:Q61188-1	Mouse	MGI:MGI:5926701|PMID:17937919
Molecular Function	GO:0005515	protein binding	Eed	IPI	PR:Q61188	Mouse	PMID:9584197
Molecular Function	GO:0005515	protein binding	Eed	IPI	PR:O09106	Mouse	PMID:12900441
Molecular Function	GO:0005515	protein binding	Eed	IPI	PR:Q923W1	Mouse	PMID:12943661
Molecular Function	GO:0005515	protein binding	Eed	IPI	PR:Q00899	Mouse	PMID:17107999
Molecular Function	GO:0005515	protein binding	Eed	IPI	PR:Q61188	Mouse	PMID:12900441
Molecular Function	GO:0005515	protein binding	Eed	IPI	PR:Q61188	Mouse	PMID:17107999
Molecular Function	GO:0005515	protein binding	Eed	IPI	PR:Q3TTC2	Mouse	PMID:21530438
Molecular Function	GO:0005515	protein binding	Eed	IPI	PR:P22227	Mouse	PMID:21530438
Molecular Function	GO:0005515	protein binding	Eed	IPI	PR:Q61188	Mouse	PMID:17997413
Molecular Function	GO:0005515	protein binding	Eed	IPI	PR:P70351	Mouse	PMID:9584197
Molecular Function	GO:0005515	protein binding	Eed	IPI	RGD:619754	Rat	PMID:24007266|RGD:9588303
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Eed	IDA		Mouse	PMID:17107999
Molecular Function	GO:0001222	transcription corepressor binding	EED	IPI	UniProtKB:Q96JN0	Human	PMID:29628311
Cellular Component	GO:0005677	chromatin silencing complex	Eed	IDA		Mouse	PMID:26658965
Cellular Component	GO:0005829	cytosol	EED	IDA		Human	GO_REF:0000052
Cellular Component	GO:0035098	ESC/E(Z) complex	EED	IDA		Human	PMID:15385962
Cellular Component	GO:0035098	ESC/E(Z) complex	EED	IDA		Human	PMID:20075857
Cellular Component	GO:0035098	ESC/E(Z) complex	EED	IDA		Human	PMID:23104054
Cellular Component	GO:0035098	ESC/E(Z) complex	EED	IDA		Human	PMID:23273982
Cellular Component	GO:0035098	ESC/E(Z) complex	Eed	IDA		Mouse	MGI:MGI:4436818|PMID:20064376
Cellular Component	GO:0035098	ESC/E(Z) complex	Eed	IDA		Mouse	MGI:MGI:5318799|PMID:22438827
Cellular Component	GO:0035098	ESC/E(Z) complex	Eed	IDA		Mouse	MGI:MGI:4429983|PMID:20144788
Cellular Component	GO:0035098	ESC/E(Z) complex	Eed	IDA		Mouse	MGI:MGI:4431292|PMID:20064375
Cellular Component	GO:0035098	ESC/E(Z) complex	Eed	IDA		Mouse	PMID:31451685
Cellular Component	GO:0005654	nucleoplasm	EED	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Eed	IDA		Mouse	PMID:11555636
Cellular Component	GO:0005634	nucleus	Eed	IDA		Mouse	PMID:19796622
Cellular Component	GO:0005634	nucleus	Eed	IDA		Mouse	PMID:22573614
Cellular Component	GO:0005634	nucleus	Eed	IDA		Mouse	PMID:18483221
Cellular Component	GO:0005634	nucleus	Eed	IDA		Mouse	PMID:9584197
Cellular Component	GO:0005634	nucleus	Eed	IDA		Rat	PMID:23354331|RGD:9588305
Cellular Component	GO:0045120	pronucleus	Eed	IDA		Mouse	PMID:12900441
Cellular Component	GO:0001739	sex chromatin	Eed	IDA		Mouse	PMID:15525528
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Eed	IEP		Mouse	PMID:20439489
Biological Process	GO:0140718	facultative heterochromatin formation	Eed	IDA		Mouse	MGI:MGI:4436818|PMID:20064376
Biological Process	GO:0140718	facultative heterochromatin formation	Eed	IDA		Mouse	MGI:MGI:4431292|PMID:20064375
Biological Process	GO:0016571	histone methylation	Eed	IMP	MGI:MGI:1856856	Mouse	PMID:15916951
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Eed	IGI	MGI:MGI:88174	Mouse	PMID:17107999
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Eed	IDA		Rat	PMID:23354331|RGD:9588305
Biological Process	GO:0048709	oligodendrocyte differentiation	Eed	IMP		Mouse	PMID:28041882
Biological Process	GO:0061087	positive regulation of histone H3-K27 methylation	Eed	IMP		Mouse	PMID:17997413
Biological Process	GO:2000011	regulation of adaxial/abaxial pattern formation	Eed	IGI	MGI:MGI:88174	Mouse	PMID:17107999
Biological Process	GO:0006349	regulation of gene expression by genomic imprinting	Eed	IMP	MGI:MGI:1856856	Mouse	PMID:12627233
Biological Process	GO:0021510	spinal cord development	Eed	IEP		Rat	PMID:20515739|RGD:9491842

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern