Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EEF1A1
  • Mouse genes Eef1a1
  • Rat genes Eef1a1,LOC100360413
  • Zfish genes eef1a1a,eef1a1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eef1a1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005516	calmodulin binding	Eef1a1	IDA		Mouse	MGI:MGI:6103758|PMID:12646217
Molecular Function	GO:1901363	heterocyclic compound binding	Eef1a1	IPI	CHEBI:90703	Rat	PMID:18218611|RGD:10401123
Molecular Function	GO:0042802	identical protein binding	Eef1a1	IPI	RGD:67387	Rat	PMID:19501573|RGD:7242926
Molecular Function	GO:0019900	kinase binding	EEF1A1	IPI	UniProtKB:Q9NRA0|UniProtKB:Q9NYA1	Human	PMID:18263879
Molecular Function	GO:0003729	mRNA binding	Eef1a1	IDA		Rat	PMID:19501573|RGD:7242926
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:P63104	Human	PMID:15161933
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:P54725	Human	PMID:16712842
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q05516	Human	PMID:16828757
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q00987	Human	PMID:17373842
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q96RQ1	Human	PMID:17980171
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q8NFJ9	Human	PMID:18000879
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q96RK4	Human	PMID:18000879
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q9BXC9	Human	PMID:18000879
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q16539	Human	PMID:18624398
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q96QB1	Human	PMID:19158340
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:P63104	Human	PMID:20618440
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q9NYA1	Human	PMID:20838377
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:P12004	Human	PMID:20849852
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q00987	Human	PMID:23260144
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:O95863	Human	PMID:24209753
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q8IUH5	Human	PMID:24705354
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q9NZ94-2	Human	PMID:25464930
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:P12004	Human	PMID:26030842
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q96T49	Human	PMID:26497934
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q14166	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q16539	Human	PMID:31980649
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q14166	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q96IK1-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:O75312	Human	PMID:9852145
Molecular Function	GO:0005515	protein binding	EEF1A1	IPI	UniProtKB:Q62384	Human	PMID:9852145
Molecular Function	GO:0005515	protein binding	Eef1a1	IPI	UniProtKB:Q64282	Mouse	MGI:MGI:5465530|PMID:19856081
Molecular Function	GO:0005515	protein binding	Eef1a1	IPI	UniProtKB:Q01534	Mouse	MGI:MGI:3829109|PMID:18649364
Molecular Function	GO:0005515	protein binding	Eef1a1	IPI	UniProtKB:O41974	Mouse	MGI:MGI:5787727|PMID:26581985
Molecular Function	GO:0005515	protein binding	Eef1a1	IPI	UniProtKB:P97343	Mouse	MGI:MGI:3835232|PMID:19015237
Molecular Function	GO:0005515	protein binding	Eef1a1	IPI	PR:Q91ZU6	Mouse	PMID:21689717
Molecular Function	GO:0005515	protein binding	Eef1a1	IPI	PR:Q6VH22	Mouse	PMID:21689717
Molecular Function	GO:0005515	protein binding	Eef1a1	IPI	PR:Q8C547	Mouse	PMID:21689717
Molecular Function	GO:0005515	protein binding	Eef1a1	IPI	PR:Q2KHI9	Mouse	PMID:21689717
Molecular Function	GO:0005515	protein binding	Eef1a1	IPI	PR:P46660	Mouse	PMID:21689717
Molecular Function	GO:0005515	protein binding	Eef1a1	IPI	PR:Q62448	Mouse	PMID:21689717
Molecular Function	GO:0005515	protein binding	Eef1a1	IPI	PR:Q6ZWR6	Mouse	PMID:21689717
Molecular Function	GO:0005515	protein binding	Eef1a1	IPI	UniProtKB:P68104	Mouse	PMID:21689717
Molecular Function	GO:0005515	protein binding	Eef1a1	IPI	PR:P13542	Mouse	PMID:21689717
Molecular Function	GO:0005515	protein binding	Eef1a1	IPI	PR:Q9QXZ0	Mouse	PMID:21689717
Molecular Function	GO:0005515	protein binding	Eef1a1	IPI	PR:Q6IR34	Mouse	PMID:21689717
Molecular Function	GO:0019901	protein kinase binding	EEF1A1	IPI	UniProtKB:P42681	Human	PMID:17177976
Molecular Function	GO:0019901	protein kinase binding	EEF1A1	IPI	UniProtKB:Q96RG2	Human	PMID:17595531
Molecular Function	GO:0003723	RNA binding	EEF1A1	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	EEF1A1	HDA		Human	PMID:22681889
Molecular Function	GO:0000049	tRNA binding	EEF1A1	IDA		Human	PMID:12426392
Cellular Component	GO:0030864	cortical actin cytoskeleton	EEF1A1	IDA		Human	PMID:19158340
Cellular Component	GO:0005737	cytoplasm	EEF1A1	IDA		Human	PMID:17177976
Cellular Component	GO:0005737	cytoplasm	EEF1A1	IDA		Human	PMID:17980171
Cellular Component	GO:0005737	cytoplasm	EEF1A1	IDA		Human	PMID:24209753
Cellular Component	GO:0005737	cytoplasm	EEF1A1	IDA		Human	PMID:8743958
Cellular Component	GO:0005737	cytoplasm	EEF1A1	IDA		Human	PMID:9852145
Cellular Component	GO:0005737	cytoplasm	Eef1a1	IDA		Mouse	MGI:MGI:5465530|PMID:19856081
Cellular Component	GO:0005737	cytoplasm	Eef1a1	IDA		Mouse	PMID:15013623
Cellular Component	GO:0005829	cytosol	EEF1A1	IDA		Human	PMID:19158340
Cellular Component	GO:0005829	cytosol	Eef1a1	IDA		Rat	PMID:18218611|RGD:10401123
Cellular Component	GO:0070062	extracellular exosome	EEF1A1	HDA		Human	PMID:12519789
Cellular Component	GO:0070062	extracellular exosome	EEF1A1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	EEF1A1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	EEF1A1	HDA		Human	PMID:20458337
Cellular Component	GO:0005615	extracellular space	EEF1A1	HDA		Human	PMID:23580065
Cellular Component	GO:0016020	membrane	EEF1A1	HDA		Human	PMID:19946888
Cellular Component	GO:0043209	myelin sheath	Eef1a1	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0005730	nucleolus	EEF1A1	IDA		Human	PMID:9852145
Cellular Component	GO:0005634	nucleus	EEF1A1	IDA		Human	PMID:17177976
Cellular Component	GO:0005634	nucleus	EEF1A1	HDA		Human	PMID:21630459
Cellular Component	GO:0005634	nucleus	EEF1A1	IDA		Human	PMID:8743958
Cellular Component	GO:0005634	nucleus	EEF1A1	IDA		Human	PMID:9852145
Cellular Component	GO:0005634	nucleus	Eef1a1	IDA		Rat	PMID:15942958|RGD:1598733
Cellular Component	GO:0005886	plasma membrane	EEF1A1	IDA		Human	PMID:26497934
Cellular Component	GO:0005886	plasma membrane	Eef1a1	IDA		Mouse	PMID:21689717
Cellular Component	GO:0032587	ruffle membrane	EEF1A1	IDA		Human	PMID:19158340
Biological Process	GO:0007568	aging	Eef1a1	IEP		Rat	PMID:12242312|RGD:10401128
Biological Process	GO:0071364	cellular response to epidermal growth factor stimulus	EEF1A1	IDA		Human	PMID:9852145
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Eef1a1	IEP		Rat	PMID:11907030|RGD:1304240
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Eef1a1	IEP		Rat	PMID:21390260|RGD:10401124
Biological Process	GO:0007507	heart development	eef1a1a	IMP	ZFIN:ZDB-MRPHLNO-171120-1	Zfish	PMID:28911200
Biological Process	GO:0007507	heart development	eef1a1a	IMP	ZFIN:ZDB-MRPHLNO-171120-2	Zfish	PMID:28911200
Biological Process	GO:1903427	negative regulation of reactive oxygen species biosynthetic process	Eef1a1	IMP		Rat	PMID:23041468|RGD:10401126
Biological Process	GO:0044829	positive regulation by host of viral genome replication	EEF1A1	IDA		Human	PMID:33495306
Biological Process	GO:0043065	positive regulation of apoptotic process	Eef1a1	IMP		Rat	PMID:16319173|RGD:10401198
Biological Process	GO:0010976	positive regulation of neuron projection development	Eef1a1	IMP		Rat	PMID:21390260|RGD:10401124
Biological Process	GO:1900022	regulation of D-erythro-sphingosine kinase activity	EEF1A1	IDA		Human	PMID:18263879

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern