Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EEF1E1
  • Mouse genes Eef1e1
  • Rat genes Eef1e1
  • Zfish genes eef1e1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eef1e1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EEF1E1	IPI	UniProtKB:Q9BTE0	Human	PMID:21516116
Molecular Function	GO:0005515	protein binding	EEF1E1	IPI	UniProtKB:P04591:PRO_0000038593	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	EEF1E1	IPI	UniProtKB:Q13137	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EEF1E1	IPI	UniProtKB:Q9BTE0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	Eef1e1	IPI	UniProtKB:Q62388|UniProtKB:Q9JKK8	Mouse	MGI:MGI:3573962|PMID:15680327
Cellular Component	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	EEF1E1	IDA		Human	PMID:19131329
Cellular Component	GO:0017101	aminoacyl-tRNA synthetase multienzyme complex	Eef1e1	IDA		Mouse	MGI:MGI:3055639|PMID:12060739
Cellular Component	GO:0005737	cytoplasm	Eef1e1	IDA		Mouse	MGI:MGI:3573962|PMID:15680327
Cellular Component	GO:0005829	cytosol	EEF1E1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	EEF1E1	IDA		Human	PMID:19289464
Cellular Component	GO:0005730	nucleolus	EEF1E1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	EEF1E1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Eef1e1	IDA		Mouse	MGI:MGI:3573962|PMID:15680327
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Eef1e1	IEP		Mouse	PMID:20439489
Biological Process	GO:0008285	negative regulation of cell population proliferation	Eef1e1	IDA		Mouse	MGI:MGI:3573962|PMID:15680327
Biological Process	GO:0043065	positive regulation of apoptotic process	Eef1e1	IMP		Mouse	MGI:MGI:3573962|PMID:15680327
Biological Process	GO:2001235	positive regulation of apoptotic signaling pathway	Eef1e1	IMP	MGI:MGI:3574590	Mouse	PMID:15680327
Biological Process	GO:2000774	positive regulation of cellular senescence	EEF1E1	IDA		Human	PMID:25465621
Biological Process	GO:0043517	positive regulation of DNA damage response, signal transduction by p53 class mediator	Eef1e1	IMP	MGI:MGI:3574590	Mouse	PMID:15680327

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern