Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Eef2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes EEF2
- Mouse genes Eef2
- Rat genes Eef2
- Zfish genes eef2a.1,eef2a.2,eef2b,eef2l2
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eef2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008097	5S rRNA binding	Eef2	IDA		Rat	PMID:3801485\|RGD:10401646
Molecular Function	GO:0051015	actin filament binding	Eef2	IDA		Rat	PMID:7988728\|RGD:10401639
Molecular Function	GO:0045296	cadherin binding	EEF2	HDA		Human	PMID:25468996
Molecular Function	GO:0003924	GTPase activity	Eef2	IDA		Mouse	PMID:22157746
Molecular Function	GO:0002039	p53 binding	Eef2	IPI	RGD:11440	Rat	PMID:12891704\|RGD:10401261
Molecular Function	GO:0005515	protein binding	EEF2	IPI	UniProtKB:Q92900	Human	PMID:19417104
Molecular Function	GO:0005515	protein binding	EEF2	IPI	UniProtKB:Q6ZRY4	Human	PMID:25064856
Molecular Function	GO:0005515	protein binding	EEF2	IPI	UniProtKB:Q96G04	Human	PMID:25231979
Molecular Function	GO:0005515	protein binding	EEF2	IPI	UniProtKB:Q99714	Human	PMID:29128334
Molecular Function	GO:0005515	protein binding	EEF2	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Eef2	IPI	PR:Q812E0	Mouse	PMID:22157746
Molecular Function	GO:0005515	protein binding	Eef2	IPI	PR:E9Q9D5	Mouse	PMID:23055941
Molecular Function	GO:0019901	protein kinase binding	EEF2	IPI	UniProtKB:P31751	Human	PMID:23823123
Molecular Function	GO:0043022	ribosome binding	EEF2	IDA		Human	PMID:23636399
Molecular Function	GO:0043022	ribosome binding	Eef2	IDA		Rat	PMID:2390990\|RGD:10401630
Molecular Function	GO:0003723	RNA binding	EEF2	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	EEF2	HDA		Human	PMID:22681889
Molecular Function	GO:0003723	RNA binding	Eef2	IDA		Rat	PMID:11681712\|RGD:10401255
Cellular Component	GO:0016235	aggresome	EEF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005737	cytoplasm	EEF2	IDA		Human	PMID:25064856
Cellular Component	GO:0005737	cytoplasm	Eef2	IDA		Mouse	MGI:MGI:3039231\|PMID:12426392
Cellular Component	GO:0005737	cytoplasm	Eef2	IDA		Rat	PMID:12891704\|RGD:10401261
Cellular Component	GO:0005829	cytosol	EEF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005829	cytosol	Eef2	IDA		Rat	PMID:10949152\|RGD:10401631
Cellular Component	GO:0070062	extracellular exosome	EEF2	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	EEF2	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	EEF2	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	EEF2	HDA		Human	PMID:23533145
Cellular Component	GO:0098978	glutamatergic synapse	Eef2	IDA		Rat	PMID:20427644\|RGD:10401235
Cellular Component	GO:0016020	membrane	EEF2	HDA		Human	PMID:19946888
Cellular Component	GO:0045121	membrane raft	Eef2	IDA		Rat	PMID:12711090\|RGD:10401640
Cellular Component	GO:0005634	nucleus	EEF2	HDA		Human	PMID:21630459
Cellular Component	GO:0005886	plasma membrane	EEF2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0042788	polysomal ribosome	Eef2	IDA		Rat	PMID:12891704\|RGD:10401261
Cellular Component	GO:0005844	polysome	Eef2	IDA		Mouse	PMID:22157746
Cellular Component	GO:1990904	ribonucleoprotein complex	EEF2	IDA		Human	PMID:18809582
Cellular Component	GO:1990904	ribonucleoprotein complex	Eef2	IDA		Rat	PMID:3801485\|RGD:10401646
Cellular Component	GO:0045202	synapse	Eef2	IDA		Mouse	PMID:16452087
Cellular Component	GO:0045202	synapse	Eef2	EXP		Mouse	PMID:16452087
Biological Process	GO:0007568	aging	Eef2	IEP		Rat	PMID:16627569\|RGD:10401265
Biological Process	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	Eef2	IEP		Rat	PMID:19625250\|RGD:10401254
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	eef2b	IDA		Zfish	PMID:18618001
Biological Process	GO:0043009	chordate embryonic development	eef2b	IMP	ZFIN:ZDB-MRPHLNO-060508-1	Zfish	PMID:16525935
Biological Process	GO:0014009	glial cell proliferation	Eef2	IEP		Rat	PMID:7696190\|RGD:10401648
Biological Process	GO:0002244	hematopoietic progenitor cell differentiation	Eef2	IMP		Mouse	PMID:24029230
Biological Process	GO:2000767	positive regulation of cytoplasmic translation	Eef2	IMP		Rat	PMID:19625250\|RGD:10401254
Biological Process	GO:0045727	positive regulation of translation	EEF2	IMP		Human	PMID:23184662
Biological Process	GO:0045727	positive regulation of translation	Eef2	IDA		Rat	PMID:2390990\|RGD:10401630
Biological Process	GO:0034976	response to endoplasmic reticulum stress	Eef2	IEP		Rat	PMID:18188169\|RGD:10401228
Biological Process	GO:0032355	response to estradiol	Eef2	IEP		Rat	PMID:16339744\|RGD:1599058
Biological Process	GO:0045471	response to ethanol	Eef2	IEP		Rat	PMID:12899944\|RGD:1599867
Biological Process	GO:0051593	response to folic acid	Eef2	IEP		Rat	PMID:12899944\|RGD:1599867
Biological Process	GO:0042542	response to hydrogen peroxide	Eef2	IEP		Rat	PMID:15211596\|RGD:10401223
Biological Process	GO:0002931	response to ischemia	Eef2	IEP		Rat	PMID:15211596\|RGD:10401223
Biological Process	GO:0009410	response to xenobiotic stimulus	Eef2	IEP		Rat	PMID:16817885\|RGD:10401257
Biological Process	GO:0035914	skeletal muscle cell differentiation	Eef2	IEP		Rat	PMID:16682826\|RGD:10401256
Biological Process	GO:0003009	skeletal muscle contraction	Eef2	IEP		Rat	PMID:19188248\|RGD:10401231
Biological Process	GO:0140242	translation at postsynapse	Eef2	IDA		Rat	PMID:20427644\|RGD:10401235
Biological Process	GO:0140242	translation at postsynapse	Eef2	IEP		Rat	PMID:20427644\|RGD:10401235
Biological Process	GO:0006414	translational elongation	Eef2	IDA		Mouse	PMID:22157746

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 11/19/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.