Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EEF2K
  • Mouse genes Eef2k
  • Rat genes Eef2k
  • Zfish genes eef2k
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eef2k

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005516	calmodulin binding	EEF2K	IDA		Human	PMID:9144159
Molecular Function	GO:0005516	calmodulin binding	Eef2k	IDA		Mouse	MGI:MGI:87674|PMID:9144159
Molecular Function	GO:0004686	elongation factor-2 kinase activity	EEF2K	IDA		Human	PMID:9144159
Molecular Function	GO:0004686	elongation factor-2 kinase activity	Eef2k	IDA		Mouse	MGI:MGI:87674|PMID:9144159
Molecular Function	GO:0004686	elongation factor-2 kinase activity	Eef2k	IMP		Rat	PMID:8663182|RGD:728659
Molecular Function	GO:0045182	translation regulator activity	Eef2k	IDA		Rat	PMID:20427644|RGD:10401235
Molecular Function	GO:0045182	translation regulator activity	Eef2k	IMP		Rat	PMID:20427644|RGD:10401235
Cellular Component	GO:0043197	dendritic spine	Eef2k	IDA		Rat	PMID:12711090|RGD:10401640
Cellular Component	GO:0098978	glutamatergic synapse	Eef2k	IDA		Rat	PMID:12711090|RGD:10401640
Cellular Component	GO:0098978	glutamatergic synapse	Eef2k	IDA		Rat	PMID:20427644|RGD:10401235
Cellular Component	GO:0098978	glutamatergic synapse	Eef2k	IMP		Rat	PMID:20427644|RGD:10401235
Cellular Component	GO:0014069	postsynaptic density	Eef2k	IDA		Rat	PMID:12711090|RGD:10401640
Biological Process	GO:0071454	cellular response to anoxia	Eef2k	IEP		Rat	PMID:12194824|RGD:8553742
Biological Process	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	Eef2k	IEP		Rat	PMID:19625250|RGD:10401254
Biological Process	GO:0071277	cellular response to calcium ion	Eef2k	IEP		Rat	PMID:19188248|RGD:10401231
Biological Process	GO:0071320	cellular response to cAMP	Eef2k	IEP		Rat	PMID:9841860|RGD:10401230
Biological Process	GO:0032869	cellular response to insulin stimulus	Eef2k	IEP		Rat	PMID:9841860|RGD:10401230
Biological Process	GO:0061300	cerebellum vasculature development	eef2k	IGI	ZFIN:ZDB-MRPHLNO-141121-2,ZFIN:ZDB-MRPHLNO-170824-6	Zfish	PMID:28429770
Biological Process	GO:0043066	negative regulation of apoptotic process	Eef2k	IMP		Rat	PMID:16227605|RGD:10401236
Biological Process	GO:0061003	positive regulation of dendritic spine morphogenesis	Eef2k	IMP		Rat	PMID:20427644|RGD:10401235
Biological Process	GO:0045807	positive regulation of endocytosis	Eef2k	IMP		Rat	PMID:18045921|RGD:10401629
Biological Process	GO:0051965	positive regulation of synapse assembly	Eef2k	IMP		Rat	PMID:20427644|RGD:10401235
Biological Process	GO:0046777	protein autophosphorylation	EEF2K	IDA		Human	PMID:23184662
Biological Process	GO:0046777	protein autophosphorylation	EEF2K	IDA		Human	PMID:9144159
Biological Process	GO:0031952	regulation of protein autophosphorylation	Eef2k	IDA		Mouse	MGI:MGI:87674|PMID:9144159
Biological Process	GO:0140245	regulation of translation at postsynapse	Eef2k	IDA		Rat	PMID:20427644|RGD:10401235
Biological Process	GO:0140245	regulation of translation at postsynapse	Eef2k	IEP		Rat	PMID:20427644|RGD:10401235
Biological Process	GO:0140245	regulation of translation at postsynapse	Eef2k	IMP		Rat	PMID:20427644|RGD:10401235
Biological Process	GO:0002931	response to ischemia	Eef2k	IEP		Rat	PMID:12920134|RGD:10401252
Biological Process	GO:1990637	response to prolactin	Eef2k	IEP		Rat	PMID:8126003|RGD:10401632

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern