Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EFEMP1
  • Mouse genes Efemp1
  • Rat genes Efemp1
  • Zfish genes efemp1,si:ch73-173h19.3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Efemp1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005006	epidermal growth factor receptor activity	EFEMP1	IDA		Human	PMID:19804359
Molecular Function	GO:0005154	epidermal growth factor receptor binding	EFEMP1	IDA		Human	PMID:19804359
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:P10398	Human	PMID:12620389
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:O43765	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:P54259	Human	PMID:16713569
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q9WMX2:PRO_0000037551	Human	PMID:18985028
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q16610	Human	PMID:19275936
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:P49639	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:O43765	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:P46379	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q12933	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q86UY0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q9NPQ8-4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:O43765	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:P50222	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:P53673	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q12933	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:O43765	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q12933	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q6FHY5	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:O43765	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:P46379	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:A8MQ03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:O43765	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:O95429	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:P03973	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:P24592	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:P32242	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q12933	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q13064	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q16740	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q3LHN2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q3LI59	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q3LI64	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q5T751	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q5TA76	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q5TA81	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q8IXL7-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q92570	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q9BQ89	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q9BYE3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q9H2F3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q9NYG5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q9UHD9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:Q9UL15	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFEMP1	IPI	UniProtKB:P42858	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Efemp1	IPI	RGD:620745	Rat	PMID:9268694|RGD:1598886
Cellular Component	GO:0005604	basement membrane	Efemp1	IDA		Rat	PMID:18803302|RGD:10401659
Cellular Component	GO:0062023	collagen-containing extracellular matrix	EFEMP1	HDA		Human	PMID:20551380
Cellular Component	GO:0062023	collagen-containing extracellular matrix	EFEMP1	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	EFEMP1	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Efemp1	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Efemp1	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0005737	cytoplasm	Efemp1	IDA		Rat	PMID:18803302|RGD:10401659
Cellular Component	GO:0070062	extracellular exosome	EFEMP1	HDA		Human	PMID:23533145
Cellular Component	GO:0005576	extracellular region	EFEMP1	HDA		Human	PMID:27068509
Cellular Component	GO:0005615	extracellular space	EFEMP1	HDA		Human	PMID:16502470
Cellular Component	GO:0005615	extracellular space	EFEMP1	IDA		Human	PMID:20005202
Cellular Component	GO:0005615	extracellular space	EFEMP1	HDA		Human	PMID:20551380
Cellular Component	GO:0005615	extracellular space	Efemp1	HDA		Mouse	MGI:MGI:5640941|PMID:24006456
Biological Process	GO:0043010	camera-type eye development	EFEMP1	IEP		Human	PMID:25406291
Biological Process	GO:0048048	embryonic eye morphogenesis	EFEMP1	IEP		Human	PMID:25406291
Biological Process	GO:0007173	epidermal growth factor receptor signaling pathway	EFEMP1	IDA		Human	PMID:19804359
Biological Process	GO:0032331	negative regulation of chondrocyte differentiation	EFEMP1	IDA		Human	PMID:20005202
Biological Process	GO:0010977	negative regulation of neuron projection development	Efemp1	IDA		Rat	PMID:18803302|RGD:10401659
Biological Process	GO:0018108	peptidyl-tyrosine phosphorylation	EFEMP1	IDA		Human	PMID:19804359
Biological Process	GO:0008284	positive regulation of cell population proliferation	Efemp1	IMP		Rat	PMID:18803302|RGD:10401659
Biological Process	GO:0031346	positive regulation of cell projection organization	Efemp1	IDA		Rat	PMID:18803302|RGD:10401659
Biological Process	GO:0031346	positive regulation of cell projection organization	Efemp1	IMP		Rat	PMID:18803302|RGD:10401659
Biological Process	GO:0048050	post-embryonic eye morphogenesis	EFEMP1	IEP		Human	PMID:25406291
Biological Process	GO:0006355	regulation of DNA-templated transcription	EFEMP1	IDA		Human	PMID:20005202
Biological Process	GO:1903975	regulation of glial cell migration	Efemp1	IDA		Rat	PMID:18803302|RGD:10401659

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern