Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EFNA5
  • Mouse genes Efna5
  • Rat genes Efna5
  • Zfish genes efna5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Efna5

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045499	chemorepellent activity	Efna5	IDA		Mouse	PMID:15996548
Molecular Function	GO:0046875	ephrin receptor binding	EFNA5	IPI	UniProtKB:P29320	Human	PMID:11519828
Molecular Function	GO:0046875	ephrin receptor binding	EFNA5	IPI	UniProtKB:P29320	Human	PMID:11870224
Molecular Function	GO:0046875	ephrin receptor binding	EFNA5	IPI	UniProtKB:Q5JZY3-2	Human	PMID:15777695
Molecular Function	GO:0046875	ephrin receptor binding	EFNA5	IPI	UniProtKB:P29317	Human	PMID:22568954
Molecular Function	GO:0046875	ephrin receptor binding	Efna5	IPI	UniProtKB:O09127	Mouse	MGI:MGI:85724|PMID:9053851
Molecular Function	GO:0046875	ephrin receptor binding	Efna5	IPI	UniProtKB:Q61772	Mouse	MGI:MGI:2182552|PMID:11089974
Molecular Function	GO:0046875	ephrin receptor binding	Efna5	IPI	UniProtKB:P54757	Rat	PMID:20824214|RGD:8554330
Molecular Function	GO:0046875	ephrin receptor binding	Efna5	IDA		Rat	PMID:7748564|RGD:728210
Molecular Function	GO:0005169	neurotrophin TRKB receptor binding	Efna5	IPI	UniProtKB:P15209	Mouse	MGI:MGI:5426777|PMID:19036963
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:P54764	Human	PMID:19836338
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:P29317	Human	PMID:20228801
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:P29317	Human	PMID:20505120
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:P54764	Human	PMID:23812375
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:O00501	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:O00590	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:O14843	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:O15529	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:O95470	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:P08034	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:P19397	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:P31937	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:P34981	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:P41181	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:P49447	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q12908	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q13520	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q5TGU0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q8N6L0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q8N6U8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q8NFU1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q8TDT2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q8TDV0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q8WWF3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q96CE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q96EC8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q96HJ5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q96Q45-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q9BSE4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q9NQQ7-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q9UBD6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNA5	IPI	UniProtKB:Q9UKG4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Efna5	IPI	UniProtKB:Q61772	Mouse	MGI:MGI:5426777|PMID:19036963
Molecular Function	GO:0005515	protein binding	Efna5	IPI	PR:Q60629	Mouse	PMID:9883724
Cellular Component	GO:0005912	adherens junction	Efna5	IDA		Mouse	PMID:23242526
Cellular Component	GO:0005604	basement membrane	Efna5	IDA		Mouse	PMID:23242526
Cellular Component	GO:0071944	cell periphery	Efna5	IDA		Mouse	PMID:23242526
Cellular Component	GO:0009897	external side of plasma membrane	EFNA5	IDA		Human	PMID:11870224
Cellular Component	GO:0098982	GABA-ergic synapse	Efna5	IEP		Mouse	PMID:22275477
Cellular Component	GO:0098982	GABA-ergic synapse	Efna5	IMP		Mouse	PMID:22275477
Cellular Component	GO:0098982	GABA-ergic synapse	Efna5	IDA		Mouse	PMID:22275477
Cellular Component	GO:0098982	GABA-ergic synapse	Efna5	IPI		Mouse	PMID:22275477
Cellular Component	GO:0005886	plasma membrane	Efna5	IDA		Mouse	MGI:MGI:5294297|PMID:17448994
Biological Process	GO:0007411	axon guidance	Efna5	IMP	MGI:MGI:2429768	Mouse	PMID:11222144
Biological Process	GO:0007411	axon guidance	Efna5	IDA		Mouse	PMID:9614241
Biological Process	GO:0007420	brain development	Efna5	IMP		Rat	PMID:7748564|RGD:728210
Biological Process	GO:0071372	cellular response to follicle-stimulating hormone stimulus	Efna5	IDA		Mouse	PMID:23242526
Biological Process	GO:1904322	cellular response to forskolin	Efna5	IDA		Mouse	PMID:23242526
Biological Process	GO:0048668	collateral sprouting	Efna5	IDA		Mouse	MGI:MGI:5426777|PMID:19036963
Biological Process	GO:0048013	ephrin receptor signaling pathway	EFNA5	IDA		Human	PMID:11870224
Biological Process	GO:0048013	ephrin receptor signaling pathway	Efna5	IDA		Mouse	MGI:MGI:5294297|PMID:17448994
Biological Process	GO:0048013	ephrin receptor signaling pathway	Efna5	IDA		Mouse	MGI:MGI:85724|PMID:9053851
Biological Process	GO:0007509	mesoderm migration involved in gastrulation	efna5b	IMP		Zfish	PMID:10381569
Biological Process	GO:1900025	negative regulation of substrate adhesion-dependent cell spreading	EFNA5	IDA		Human	PMID:23242526
Biological Process	GO:0048672	positive regulation of collateral sprouting	Efna5	IMP		Mouse	MGI:MGI:5426777|PMID:19036963
Biological Process	GO:0050731	positive regulation of peptidyl-tyrosine phosphorylation	Efna5	IDA		Mouse	MGI:MGI:5294297|PMID:17448994
Biological Process	GO:0051965	positive regulation of synapse assembly	Efna5	IDA		Mouse	MGI:MGI:5426777|PMID:19036963
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	EFNA5	IDA		Human	PMID:11870224
Biological Process	GO:0032956	regulation of actin cytoskeleton organization	Efna5	IDA		Mouse	MGI:MGI:5294297|PMID:17448994
Biological Process	GO:0022604	regulation of cell morphogenesis	EFNA5	IDA		Human	PMID:23242526
Biological Process	GO:0022407	regulation of cell-cell adhesion	EFNA5	IDA		Human	PMID:11870224
Biological Process	GO:0022407	regulation of cell-cell adhesion	Efna5	IDA		Mouse	MGI:MGI:2182552|PMID:11089974
Biological Process	GO:0051893	regulation of focal adhesion assembly	EFNA5	IDA		Human	PMID:11870224
Biological Process	GO:0043087	regulation of GTPase activity	EFNA5	IDA		Human	PMID:11870224
Biological Process	GO:0043087	regulation of GTPase activity	Efna5	IDA		Mouse	MGI:MGI:5294297|PMID:17448994
Biological Process	GO:0061178	regulation of insulin secretion involved in cellular response to glucose stimulus	Efna5	IMP		Mouse	MGI:MGI:5294297|PMID:17448994
Biological Process	GO:0070507	regulation of microtubule cytoskeleton organization	EFNA5	IDA		Human	PMID:11870224
Biological Process	GO:0031290	retinal ganglion cell axon guidance	Efna5	IDA		Mouse	PMID:15996548
Biological Process	GO:0001756	somitogenesis	efna5b	IMP		Zfish	PMID:10381569
Biological Process	GO:0099560	synaptic membrane adhesion	Efna5	IEP		Mouse	PMID:22275477
Biological Process	GO:0099560	synaptic membrane adhesion	Efna5	IDA		Mouse	PMID:22275477
Biological Process	GO:0099560	synaptic membrane adhesion	Efna5	IPI		Mouse	PMID:22275477
Biological Process	GO:0099560	synaptic membrane adhesion	Efna5	IMP		Mouse	PMID:22275477

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern