Comparative GO Graph (mouse, human, rat, zebrafish)

Source

Alliance of Genome Resources

Compare experimental GO annotations for Human-Mouse-Rat-Zebrafish orthologs to Mouse Efnb2

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

This class contains
- Human genes EFNB2
- Mouse genes Efnb2
- Rat genes Efnb2
- Zfish genes efnb2a,efnb2b
Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Efnb2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046875	ephrin receptor binding	EFNB2	IPI	UniProtKB:P54760	Human	PMID:16867992
Molecular Function	GO:0005515	protein binding	EFNB2	IPI	UniProtKB:O43639	Human	PMID:12606549
Molecular Function	GO:0005515	protein binding	EFNB2	IPI	UniProtKB:O43639	Human	PMID:15764601
Molecular Function	GO:0005515	protein binding	EFNB2	IPI	UniProtKB:O89343	Human	PMID:18488039
Molecular Function	GO:0005515	protein binding	EFNB2	IPI	UniProtKB:Q9IH62	Human	PMID:18488039
Molecular Function	GO:0005515	protein binding	EFNB2	IPI	UniProtKB:P54764	Human	PMID:19836338
Molecular Function	GO:0005515	protein binding	EFNB2	IPI	UniProtKB:P54760	Human	PMID:26481148
Molecular Function	GO:0005515	protein binding	EFNB2	IPI	UniProtKB:P54760	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EFNB2	IPI	UniProtKB:Q9IH62	Human	PMID:28904190
Molecular Function	GO:0005515	protein binding	EFNB2	IPI	UniProtKB:Q86W74-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EFNB2	IPI	UniProtKB:P54760	Human	PMID:35384245
Molecular Function	GO:0005515	protein binding	Efnb2	IPI	UniProtKB:Q03137	Mouse	MGI:MGI:3810017\|PMID:18555774
Molecular Function	GO:0005515	protein binding	Efnb2	IPI	UniProtKB:P12931	Mouse	MGI:MGI:3619856\|PMID:16511561
Molecular Function	GO:0005515	protein binding	Efnb2	IPI	UniProtKB:O88797	Mouse	MGI:MGI:5476876\|PMID:23354168
Molecular Function	GO:0005102	signaling receptor binding	Efnb2	IPI	PR:P54763	Mouse	PMID:11780069
Cellular Component	GO:0030425	dendrite	Efnb2	IDA		Rat	PMID:17626212\|RGD:152995392
Cellular Component	GO:0005925	focal adhesion	EFNB2	HDA		Human	PMID:21423176
Cellular Component	GO:0098978	glutamatergic synapse	Efnb2	IDA		Mouse	PMID:11754836
Cellular Component	GO:0098978	glutamatergic synapse	Efnb2	IMP		Mouse	PMID:11754836
Cellular Component	GO:0098978	glutamatergic synapse	Efnb2	IDA		Mouse	PMID:19160501
Cellular Component	GO:0098978	glutamatergic synapse	Efnb2	IMP		Mouse	PMID:19160501
Cellular Component	GO:0098978	glutamatergic synapse	Efnb2	IPI		Mouse	PMID:19160501
Cellular Component	GO:0098978	glutamatergic synapse	Efnb2	IEP		Mouse	PMID:19160501
Cellular Component	GO:0098978	glutamatergic synapse	Efnb2	IDA		Mouse	PMID:14699416
Cellular Component	GO:0098978	glutamatergic synapse	Efnb2	IDA		Rat	PMID:19915143\|RGD:13702172
Cellular Component	GO:0098978	glutamatergic synapse	Efnb2	IMP		Rat	PMID:19915143\|RGD:13702172
Cellular Component	GO:0005886	plasma membrane	EFNB2	IDA		Human	PMID:17251577
Cellular Component	GO:0005886	plasma membrane	EFNB2	IDA		Human	PMID:28931592
Cellular Component	GO:0005886	plasma membrane	Efnb2	IDA		Mouse	PMID:15223334
Cellular Component	GO:0098839	postsynaptic density membrane	Efnb2	IDA		Mouse	PMID:14699416
Cellular Component	GO:0042734	presynaptic membrane	Efnb2	IDA		Rat	PMID:19915143\|RGD:13702172
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Efnb2	IDA		Mouse	PMID:11754836
Cellular Component	GO:0098685	Schaffer collateral - CA1 synapse	Efnb2	IMP		Mouse	PMID:11754836
Biological Process	GO:0034332	adherens junction organization	Efnb2	IDA		Mouse	MGI:MGI:6316556\|PMID:30639848
Biological Process	GO:0035475	angioblast cell migration involved in selective angioblast sprouting	efnb2a	IMP	ZFIN:ZDB-MRPHLNO-050523-1	Zfish	PMID:19815777
Biological Process	GO:0009887	animal organ morphogenesis	Efnb2	IMP	MGI:MGI:3051214	Mouse	PMID:15223334
Biological Process	GO:0009887	animal organ morphogenesis	Efnb2	IMP	MGI:MGI:3051215	Mouse	PMID:15223334
Biological Process	GO:0009952	anterior/posterior pattern specification	efnb2a	IGI	ZFIN:ZDB-MRPHLNO-050522-1,ZFIN:ZDB-MRPHLNO-050523-1	Zfish	PMID:15797022
Biological Process	GO:0007412	axon target recognition	efnb2a	IDA		Zfish	PMID:17507550
Biological Process	GO:0007412	axon target recognition	efnb2a	IMP		Zfish	PMID:17507550
Biological Process	GO:0001568	blood vessel development	efnb2b	IGI	ZFIN:ZDB-GENE-990415-67	Zfish	PMID:25834021
Biological Process	GO:0001568	blood vessel development	efnb2a	IGI	ZFIN:ZDB-GENE-010618-1	Zfish	PMID:25834021
Biological Process	GO:0001568	blood vessel development	efnb2a	IGI	ZFIN:ZDB-GENE-040109-4	Zfish	PMID:25834021
Biological Process	GO:0048514	blood vessel morphogenesis	Efnb2	IMP	MGI:MGI:3051215	Mouse	PMID:19571816
Biological Process	GO:0048514	blood vessel morphogenesis	Efnb2	IMP	MGI:MGI:3051214	Mouse	PMID:19571816
Biological Process	GO:0007155	cell adhesion	EFNB2	IDA		Human	PMID:12734395
Biological Process	GO:0002042	cell migration involved in sprouting angiogenesis	EFNB2	IDA		Human	PMID:12734395
Biological Process	GO:0071222	cellular response to lipopolysaccharide	Efnb2	IEP		Rat	PMID:33794069\|RGD:127285659
Biological Process	GO:0048013	ephrin receptor signaling pathway	EFNB2	IDA		Human	PMID:12734395
Biological Process	GO:0043616	keratinocyte proliferation	Efnb2	IMP	MGI:MGI:2176538,MGI:MGI:4430073	Mouse	PMID:19571816
Biological Process	GO:0070121	Kupffer's vesicle development	efnb2b	IMP	ZFIN:ZDB-MRPHLNO-161004-5	Zfish	PMID:27287807
Biological Process	GO:0001945	lymph vessel development	Efnb2	IMP	MGI:MGI:3573787	Mouse	PMID:15687262
Biological Process	GO:0010839	negative regulation of keratinocyte proliferation	Efnb2	IMP	MGI:MGI:2176538,MGI:MGI:4430073	Mouse	PMID:19571816
Biological Process	GO:0010977	negative regulation of neuron projection development	EFNB2	IDA		Human	PMID:10066262
Biological Process	GO:0072178	nephric duct morphogenesis	Efnb2	IMP	MGI:MGI:3026687	Mouse	PMID:25139858
Biological Process	GO:0003404	optic vesicle morphogenesis	efnb2a	IMP	ZFIN:ZDB-GENO-100510-15	Zfish	PMID:24026122
Biological Process	GO:0003404	optic vesicle morphogenesis	efnb2a	IGI	ZFIN:ZDB-MRPHLNO-050523-1,ZFIN:ZDB-MRPHLNO-131219-1	Zfish	PMID:24026122
Biological Process	GO:0003404	optic vesicle morphogenesis	efnb2a	IGI	ZFIN:ZDB-MRPHLNO-050522-1,ZFIN:ZDB-MRPHLNO-050523-1,ZFIN:ZDB-MRPHLNO-131219-1	Zfish	PMID:24026122
Biological Process	GO:1903849	positive regulation of aorta morphogenesis	Efnb2	IMP	MGI:MGI:2176476	Mouse	PMID:18952909
Biological Process	GO:1903849	positive regulation of aorta morphogenesis	Efnb2	IMP	MGI:MGI:3526818	Mouse	PMID:18952909
Biological Process	GO:2000727	positive regulation of cardiac muscle cell differentiation	Efnb2	IMP		Mouse	MGI:MGI:3701380\|PMID:17336907
Biological Process	GO:0008284	positive regulation of cell population proliferation	EFNB2	IMP		Human	PMID:26268439
Biological Process	GO:1901216	positive regulation of neuron death	EFNB2	IDA		Human	PMID:10066262
Biological Process	GO:0099054	presynapse assembly	Efnb2	IDA		Rat	PMID:19915143\|RGD:13702172
Biological Process	GO:0099054	presynapse assembly	Efnb2	IMP		Rat	PMID:19915143\|RGD:13702172
Biological Process	GO:0050920	regulation of chemotaxis	EFNB2	IDA		Human	PMID:12734395
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Efnb2	IDA		Mouse	PMID:11754836
Biological Process	GO:0099072	regulation of postsynaptic membrane neurotransmitter receptor levels	Efnb2	IMP		Mouse	PMID:11754836
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Efnb2	IMP		Mouse	PMID:19160501
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Efnb2	IDA		Mouse	PMID:19160501
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Efnb2	IPI		Mouse	PMID:19160501
Biological Process	GO:0099149	regulation of postsynaptic neurotransmitter receptor internalization	Efnb2	IEP		Mouse	PMID:19160501
Biological Process	GO:0021654	rhombomere boundary formation	efnb2a	IGI	ZFIN:ZDB-MRPHLNO-050522-1,ZFIN:ZDB-MRPHLNO-050712-3	Zfish	PMID:19135438
Biological Process	GO:0021654	rhombomere boundary formation	efnb2a	IGI	ZFIN:ZDB-MRPHLNO-050522-1,ZFIN:ZDB-MRPHLNO-050523-1	Zfish	PMID:15797022
Biological Process	GO:0001756	somitogenesis	efnb2a	IGI	ZFIN:ZDB-GENO-100512-3,ZFIN:ZDB-MRPHLNO-050712-3	Zfish	PMID:23192979
Biological Process	GO:0001756	somitogenesis	efnb2a	IGI	ZFIN:ZDB-GENO-050713-2	Zfish	PMID:15809040
Biological Process	GO:0001756	somitogenesis	efnb2a	IGI	ZFIN:ZDB-GENO-100512-2,ZFIN:ZDB-MRPHLNO-050712-3	Zfish	PMID:23192979
Biological Process	GO:0001756	somitogenesis	efnb2a	IMP	ZFIN:ZDB-MRPHLNO-050712-3	Zfish	PMID:15809040
Biological Process	GO:0008039	synaptic target recognition	efnb2a	IEP		Zfish	PMID:15007827
Biological Process	GO:0031295	T cell costimulation	Efnb2	IDA		Mouse	PMID:15599401
Biological Process	GO:0048845	venous blood vessel morphogenesis	Efnb2	IMP	MGI:MGI:3526818	Mouse	PMID:18952909
Biological Process	GO:0048845	venous blood vessel morphogenesis	Efnb2	IMP	MGI:MGI:2176476	Mouse	PMID:18952909

Gene Ontology Evidence Code Abbreviations:

EXP Inferred from experiment

IDA Inferred from direct assay

IEP Inferred from expression pattern

IGI Inferred from genetic interaction

IMP Inferred from mutant phenotype

IPI Inferred from physical interaction

HTP Inferred from High Throughput Experiment

HDA Inferred from High Throughput Direct Assay

HMP Inferred from High Throughput Mutant Phenotype

HGI Inferred from High Throughput Genetic Interaction

HEP Inferred from High Throughput Expression Pattern

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources Funding Information Warranty Disclaimer, Privacy Notice, Licensing, & Copyright Send questions and comments to User Support.	last database update 12/10/2024 MGI 6.24

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023. Complete table of the annotations represented in this image is provided below.

Molecular Function

Cellular Component

Biological Process

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.