Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EFNB3
  • Mouse genes Efnb3
  • Rat genes Efnb3
  • Zfish genes efnb3a,efnb3b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Efnb3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0046875	ephrin receptor binding	EFNB3	IPI	UniProtKB:P29320	Human	PMID:11519828
Molecular Function	GO:0046875	ephrin receptor binding	EFNB3	IDA		Human	PMID:8808709
Molecular Function	GO:0005515	protein binding	EFNB3	IPI	UniProtKB:P54764	Human	PMID:23812375
Molecular Function	GO:0005515	protein binding	EFNB3	IPI	UniProtKB:P54764	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	Efnb3	IPI	UniProtKB:Q4VCP5	Mouse	MGI:MGI:6093124|PMID:18632560
Cellular Component	GO:0098978	glutamatergic synapse	Efnb3	IDA		Mouse	PMID:16571754
Cellular Component	GO:0098978	glutamatergic synapse	Efnb3	IMP		Mouse	PMID:16571754
Cellular Component	GO:0098978	glutamatergic synapse	Efnb3	IDA		Rat	PMID:26479588|RGD:13702249
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Efnb3	IDA		Mouse	PMID:16571754
Cellular Component	GO:0098686	hippocampal mossy fiber to CA3 synapse	Efnb3	IMP		Mouse	PMID:16571754
Cellular Component	GO:0005886	plasma membrane	EFNB3	IDA		Human	PMID:17251577
Cellular Component	GO:0098839	postsynaptic density membrane	Efnb3	IDA		Rat	PMID:26479588|RGD:13702249
Cellular Component	GO:0042734	presynaptic membrane	Efnb3	IDA		Mouse	PMID:16571754
Biological Process	GO:0007628	adult walking behavior	Efnb3	IMP	MGI:MGI:3026700	Mouse	PMID:11182083
Biological Process	GO:0007628	adult walking behavior	Efnb3	IMP	MGI:MGI:2388046	Mouse	PMID:12649481
Biological Process	GO:0016198	axon choice point recognition	Efnb3	IMP	MGI:MGI:3026700	Mouse	PMID:11182083
Biological Process	GO:0007411	axon guidance	Efnb3	IMP	MGI:MGI:2388046	Mouse	PMID:12649481
Biological Process	GO:0007411	axon guidance	Efnb3	IMP		Mouse	PMID:11731465
Biological Process	GO:0048013	ephrin receptor signaling pathway	EFNB3	IDA		Human	PMID:8808709
Biological Process	GO:0050771	negative regulation of axonogenesis	Efnb3	IDA		Mouse	MGI:MGI:5905553|PMID:12383247
Biological Process	GO:1905608	positive regulation of presynapse assembly	Efnb3	IMP		Rat	PMID:17626212|RGD:152995392
Biological Process	GO:0050806	positive regulation of synaptic transmission	Efnb3	IMP		Rat	PMID:17626212|RGD:152995392
Biological Process	GO:0021654	rhombomere boundary formation	efnb3b	IMP	ZFIN:ZDB-MRPHLNO-120814-4	Zfish	PMID:22764046
Biological Process	GO:0031295	T cell costimulation	Efnb3	IDA		Mouse	PMID:15599401
Biological Process	GO:0099557	trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission	Efnb3	IMP		Mouse	PMID:16571754
Biological Process	GO:0099557	trans-synaptic signaling by trans-synaptic complex, modulating synaptic transmission	Efnb3	IDA		Mouse	PMID:16571754

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern