Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EGFL7
  • Mouse genes Egfl7
  • Rat genes Egfl7
  • Zfish genes egfl7
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Egfl7

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005112	Notch binding	Egfl7	IPI	PR:P31695	Mouse	PMID:20947685
Molecular Function	GO:0005515	protein binding	EGFL7	IPI	UniProtKB:P49639	Human	PMID:21653829
Molecular Function	GO:0005515	protein binding	EGFL7	IPI	UniProtKB:A6NK89	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGFL7	IPI	UniProtKB:O14964	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGFL7	IPI	UniProtKB:P49639	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGFL7	IPI	UniProtKB:Q96MH2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGFL7	IPI	UniProtKB:Q99932-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGFL7	IPI	UniProtKB:Q9H2F3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGFL7	IPI	UniProtKB:Q9UJV3-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGFL7	IPI	UniProtKB:Q9Y223-2	Human	PMID:32296183
Cellular Component	GO:0062023	collagen-containing extracellular matrix	EGFL7	HDA		Human	PMID:23658023
Cellular Component	GO:0062023	collagen-containing extracellular matrix	EGFL7	HDA		Human	PMID:25037231
Cellular Component	GO:0062023	collagen-containing extracellular matrix	EGFL7	HDA		Human	PMID:28675934
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Egfl7	HDA		Mouse	MGI:MGI:6201853|PMID:28071719
Cellular Component	GO:0062023	collagen-containing extracellular matrix	Egfl7	HDA		Mouse	MGI:MGI:6201834|PMID:22159717
Cellular Component	GO:0005576	extracellular region	Egfl7	IDA		Mouse	MGI:MGI:3042772|PMID:15162510
Cellular Component	GO:0005615	extracellular space	Egfl7	IDA		Mouse	PMID:14592969
Biological Process	GO:0001568	blood vessel development	Egfl7	IEP		Mouse	MGI:MGI:3044237|PMID:15085134
Biological Process	GO:0045746	negative regulation of Notch signaling pathway	EGFL7	IMP		Human	PMID:20947685
Biological Process	GO:0014912	negative regulation of smooth muscle cell migration	Egfl7	IDA		Mouse	PMID:14592969
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	EGFL7	IMP		Human	PMID:20947685
Biological Process	GO:0014909	smooth muscle cell migration	Egfl7	IDA		Mouse	PMID:14592969
Biological Process	GO:0001570	vasculogenesis	Egfl7	IEP		Mouse	MGI:MGI:3042772|PMID:15162510
Biological Process	GO:0001570	vasculogenesis	egfl7	IMP	ZFIN:ZDB-MRPHLNO-080723-1	Zfish	PMID:18300411
Biological Process	GO:0001570	vasculogenesis	egfl7	IMP		Zfish	PMID:15085134

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern