Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EGLN2
  • Mouse genes Egln2
  • Rat genes Egln2
  • Zfish genes egln2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Egln2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016706	2-oxoglutarate-dependent dioxygenase activity	EGLN2	IDA		Human	PMID:11595184
Molecular Function	GO:0016706	2-oxoglutarate-dependent dioxygenase activity	EGLN2	IDA		Human	PMID:22955912
Molecular Function	GO:0008198	ferrous iron binding	EGLN2	IDA		Human	PMID:28594552
Molecular Function	GO:0019826	oxygen sensor activity	EGLN2	IDA		Human	PMID:11595184
Molecular Function	GO:0031545	peptidyl-proline 4-dioxygenase activity	EGLN2	IDA		Human	PMID:11598268
Molecular Function	GO:0031545	peptidyl-proline 4-dioxygenase activity	EGLN2	IDA		Human	PMID:12039559
Molecular Function	GO:0031545	peptidyl-proline 4-dioxygenase activity	Egln2	IDA		Rat	PMID:15925519|RGD:13602003
Molecular Function	GO:0005515	protein binding	EGLN2	IPI	UniProtKB:Q16665	Human	PMID:16511565
Molecular Function	GO:0005515	protein binding	EGLN2	IPI	UniProtKB:Q16665	Human	PMID:17353276
Molecular Function	GO:0005515	protein binding	EGLN2	IPI	UniProtKB:A6NIX2	Human	PMID:22286099
Molecular Function	GO:0005515	protein binding	EGLN2	IPI	UniProtKB:Q96IF1	Human	PMID:22286099
Molecular Function	GO:0005515	protein binding	EGLN2	IPI	UniProtKB:Q9UGP4	Human	PMID:22286099
Cellular Component	GO:0005654	nucleoplasm	EGLN2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	EGLN2	IDA		Human	GO_REF:0000054
Cellular Component	GO:0005634	nucleus	EGLN2	IDA		Human	PMID:11850811
Cellular Component	GO:0005634	nucleus	EGLN2	IDA		Human	PMID:12615973
Biological Process	GO:0045454	cell redox homeostasis	EGLN2	IDA		Human	PMID:11595184
Biological Process	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	EGLN2	IDA		Human	PMID:11598268
Biological Process	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	EGLN2	IDA		Human	PMID:12039559
Biological Process	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	Egln2	IDA		Rat	PMID:15925519|RGD:13602003
Biological Process	GO:0045732	positive regulation of protein catabolic process	EGLN2	IDA		Human	PMID:11595184
Biological Process	GO:0043523	regulation of neuron apoptotic process	EGLN2	IMP		Human	PMID:19587290
Biological Process	GO:0001666	response to hypoxia	EGLN2	IDA		Human	PMID:11595184

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern