Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EGLN3
  • Mouse genes Egln3
  • Rat genes Egln3
  • Zfish genes egln3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Egln3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0016706	2-oxoglutarate-dependent dioxygenase activity	EGLN3	IDA		Human	PMID:22955912
Molecular Function	GO:0031545	peptidyl-proline 4-dioxygenase activity	EGLN3	IDA		Human	PMID:11598268
Molecular Function	GO:0031543	peptidyl-proline dioxygenase activity	Egln3	IDA		Mouse	PMID:24030251
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q13438	Human	PMID:15721254
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q16665	Human	PMID:15721254
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q16665	Human	PMID:16511565
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q16665	Human	PMID:17353276
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:P07550	Human	PMID:19584355
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:P10415	Human	PMID:20849813
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q02962	Human	PMID:21575608
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:P14618-1	Human	PMID:21620138
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q16659	Human	PMID:21988832
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:A6NIX2	Human	PMID:22286099
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q96IF1	Human	PMID:22286099
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q9UGP4	Human	PMID:22286099
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:D0VY79	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q04864	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q53GC0	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q5JST6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q6IBW4-4	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q6PF05-3	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q9NYB9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q9P0K8	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q04864	Human	PMID:26972000
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q13438	Human	PMID:26972000
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q16659	Human	PMID:26972000
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q16665	Human	PMID:26972000
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q16665	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:A1KXE4-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:O15499	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:O43679	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:P56545-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q13123	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q16829	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q8N720	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q8NC74	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q96GY0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q96HA8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q9HB19	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q9P0K8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EGLN3	IPI	UniProtKB:Q9UKT9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Egln3	IPI	UniProtKB:P49950	Rat	PMID:20849813|RGD:8553662
Cellular Component	GO:0005737	cytoplasm	EGLN3	IDA		Human	PMID:12615973
Cellular Component	GO:0005829	cytosol	EGLN3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	EGLN3	IDA		Human	PMID:12615973
Biological Process	GO:0006919	activation of cysteine-type endopeptidase activity involved in apoptotic process	EGLN3	IEP		Human	PMID:20978507
Biological Process	GO:0006915	apoptotic process	EGLN3	IEP		Human	PMID:20978507
Biological Process	GO:1990830	cellular response to leukemia inhibitory factor	Egln3	IEP		Mouse	PMID:20439489
Biological Process	GO:0050687	negative regulation of defense response to virus	egln3	IMP	ZFIN:ZDB-GENO-210415-10	Zfish	PMID:32669312
Biological Process	GO:0018401	peptidyl-proline hydroxylation to 4-hydroxy-L-proline	EGLN3	IDA		Human	PMID:11598268
Biological Process	GO:0018126	protein hydroxylation	EGLN3	IDA		Human	PMID:19584355
Biological Process	GO:0042127	regulation of cell population proliferation	EGLN3	IEP		Human	PMID:20978507
Biological Process	GO:0042127	regulation of cell population proliferation	Egln3	IMP		Mouse	MGI:MGI:3794960|PMID:18332118
Biological Process	GO:0042127	regulation of cell population proliferation	Egln3	IMP		Rat	PMID:12379765|RGD:728483
Biological Process	GO:0043523	regulation of neuron apoptotic process	Egln3	IMP		Mouse	MGI:MGI:3794960|PMID:18332118
Biological Process	GO:0001666	response to hypoxia	EGLN3	IEP		Human	PMID:20978507

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern