Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EGR3
  • Mouse genes Egr3
  • Rat genes Egr3
  • Zfish genes egr3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Egr3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	Egr3	IDA		Mouse	MGI:MGI:5905274|PMID:14560009
Molecular Function	GO:0043565	sequence-specific DNA binding	Egr3	IDA		Mouse	MGI:MGI:5902677|PMID:23332764
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	EGR3	IDA		Human	PMID:28473536
Cellular Component	GO:0045202	synapse	Egr3	IMP	MGI:MGI:2180063	Mouse	MGI:MGI:2178914|PMID:11978828
Biological Process	GO:0002042	cell migration involved in sprouting angiogenesis	EGR3	IDA		Human	PMID:18059339
Biological Process	GO:0044344	cellular response to fibroblast growth factor stimulus	EGR3	IMP		Human	PMID:18059339
Biological Process	GO:0035924	cellular response to vascular endothelial growth factor stimulus	EGR3	IMP		Human	PMID:18059339
Biological Process	GO:0035767	endothelial cell chemotaxis	EGR3	IMP		Human	PMID:18059339
Biological Process	GO:0043066	negative regulation of apoptotic process	EGR3	IMP		Human	PMID:18059339
Biological Process	GO:0007274	neuromuscular synaptic transmission	Egr3	IMP	MGI:MGI:2180063	Mouse	PMID:11978828
Biological Process	GO:0007422	peripheral nervous system development	Egr3	IMP	MGI:MGI:2180063	Mouse	PMID:15582775
Biological Process	GO:0001938	positive regulation of endothelial cell proliferation	EGR3	IMP		Human	PMID:18059339
Biological Process	GO:0033089	positive regulation of T cell differentiation in thymus	Egr3	IMP		Mouse	PMID:21737317
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Egr3	IDA		Mouse	MGI:MGI:5905274|PMID:14560009
Biological Process	GO:0045586	regulation of gamma-delta T cell differentiation	Egr3	IDA		Mouse	PMID:21737317

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern