Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EHD1
  • Mouse genes Ehd1
  • Rat genes Ehd1
  • Zfish genes ehd1a,ehd1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ehd1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	EHD1	HDA		Human	PMID:25468996
Molecular Function	GO:0042802	identical protein binding	EHD1	IPI	UniProtKB:Q9H4M9	Human	PMID:12121420
Molecular Function	GO:0042802	identical protein binding	EHD1	IPI	UniProtKB:Q9H4M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHD1	IPI	UniProtKB:Q9QXY6	Human	PMID:12121420
Molecular Function	GO:0005515	protein binding	EHD1	IPI	UniProtKB:E1B9V6	Human	PMID:15020713
Molecular Function	GO:0005515	protein binding	EHD1	IPI	UniProtKB:Q9H1K0	Human	PMID:15020713
Molecular Function	GO:0005515	protein binding	EHD1	IPI	UniProtKB:Q9H223	Human	PMID:17233914
Molecular Function	GO:0005515	protein binding	EHD1	IPI	UniProtKB:Q9NZN3	Human	PMID:17233914
Molecular Function	GO:0005515	protein binding	EHD1	IPI	UniProtKB:Q9NZN4	Human	PMID:17233914
Molecular Function	GO:0005515	protein binding	EHD1	IPI	UniProtKB:Q8N3F8	Human	PMID:19864458
Molecular Function	GO:0005515	protein binding	EHD1	IPI	UniProtKB:Q8N3F8	Human	PMID:22284051
Molecular Function	GO:0005515	protein binding	EHD1	IPI	UniProtKB:Q9P2R3	Human	PMID:22284051
Molecular Function	GO:0005515	protein binding	EHD1	IPI	UniProtKB:Q9UNF0	Human	PMID:23596323
Molecular Function	GO:0005515	protein binding	EHD1	IPI	UniProtKB:Q9NZN3	Human	PMID:26226295
Molecular Function	GO:0005515	protein binding	EHD1	IPI	UniProtKB:Q8N3F8	Human	PMID:27189942
Molecular Function	GO:0005515	protein binding	EHD1	IPI	UniProtKB:Q9P2R3	Human	PMID:27189942
Molecular Function	GO:0005515	protein binding	EHD1	IPI	UniProtKB:Q9H1K0	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EHD1	IPI	UniProtKB:O95721	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHD1	IPI	UniProtKB:Q9NZN3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ehd1	IPI	PR:Q69ZW3	Mouse	PMID:15247266
Molecular Function	GO:0005515	protein binding	Ehd1	IPI	PR:Q9QXY6	Mouse	PMID:12121420
Molecular Function	GO:0005515	protein binding	Ehd1	IPI	PR:Q8C8R3	Mouse	PMID:20489164
Molecular Function	GO:0005515	protein binding	Ehd1	IPI	RGD:2869|RGD:620225	Rat	PMID:11423532|RGD:1579732
Molecular Function	GO:0005515	protein binding	Ehd1	IPI	UniProtKB:Q9QY17	Rat	PMID:15371016|RGD:8554498
Molecular Function	GO:0005515	protein binding	Ehd1	IPI	UniProtKB:Q9Z2P6	Rat	PMID:15371016|RGD:8554498
Molecular Function	GO:0031267	small GTPase binding	EHD1	IPI	UniProtKB:P61006	Human	PMID:19864458
Cellular Component	GO:0020018	ciliary pocket membrane	EHD1	IDA		Human	PMID:25686250
Cellular Component	GO:0005769	early endosome	Ehd1	IDA		Mouse	PMID:11389441
Cellular Component	GO:0031901	early endosome membrane	EHD1	IDA		Human	PMID:15020713
Cellular Component	GO:0030139	endocytic vesicle	Ehd1	IDA		Mouse	PMID:12121420
Cellular Component	GO:0005768	endosome	Ehd1	IDA		Mouse	PMID:15247266
Cellular Component	GO:0010008	endosome membrane	Ehd1	IDA		Rat	PMID:23572513|RGD:8554201
Cellular Component	GO:0070062	extracellular exosome	EHD1	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	EHD1	HDA		Human	PMID:19199708
Cellular Component	GO:0070062	extracellular exosome	EHD1	HDA		Human	PMID:20458337
Cellular Component	GO:0070062	extracellular exosome	EHD1	HDA		Human	PMID:23533145
Cellular Component	GO:0005811	lipid droplet	Ehd1	IDA		Mouse	MGI:MGI:3711403|PMID:17451652
Cellular Component	GO:0016020	membrane	EHD1	HDA		Human	PMID:19946888
Cellular Component	GO:0043209	myelin sheath	Ehd1	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Ehd1	IDA		Mouse	PMID:20489164
Cellular Component	GO:0005886	plasma membrane	Ehd1	IDA		Mouse	MGI:MGI:5487527|PMID:21177873
Cellular Component	GO:0005886	plasma membrane	Ehd1	IDA		Mouse	PMID:15247266
Cellular Component	GO:0031095	platelet dense tubular network membrane	Ehd1	IDA		Mouse	MGI:MGI:3711403|PMID:17451652
Cellular Component	GO:0055038	recycling endosome membrane	EHD1	IDA		Human	PMID:15020713
Cellular Component	GO:0055038	recycling endosome membrane	EHD1	IDA		Human	PMID:17233914
Cellular Component	GO:0055038	recycling endosome membrane	EHD1	IDA		Human	PMID:19864458
Cellular Component	GO:0055038	recycling endosome membrane	EHD1	IDA		Human	PMID:23596323
Biological Process	GO:1990090	cellular response to nerve growth factor stimulus	Ehd1	IDA		Rat	PMID:23572513|RGD:8554201
Biological Process	GO:0042632	cholesterol homeostasis	Ehd1	IMP		Mouse	MGI:MGI:3711403|PMID:17451652
Biological Process	GO:0060271	cilium assembly	EHD1	IMP		Human	PMID:25686250
Biological Process	GO:0060271	cilium assembly	Ehd1	IMP		Mouse	MGI:MGI:5770034|PMID:25686250
Biological Process	GO:0060271	cilium assembly	ehd1b	IMP		Zfish	PMID:25686250|ZFIN:ZDB-PUB-150429-18
Biological Process	GO:0060271	cilium assembly	ehd1a	IMP		Zfish	PMID:25686250|ZFIN:ZDB-PUB-150429-18
Biological Process	GO:0032456	endocytic recycling	EHD1	IMP		Human	PMID:15020713
Biological Process	GO:0032456	endocytic recycling	EHD1	IGI	UniProtKB:G5ECC3,UniProtKB:G5EEU7	Human	PMID:17233914
Biological Process	GO:0006897	endocytosis	EHD1	IMP		Human	PMID:20801876
Biological Process	GO:0006897	endocytosis	Ehd1	IDA		Mouse	PMID:15247266
Biological Process	GO:0016197	endosomal transport	Ehd1	IDA		Mouse	PMID:11389441
Biological Process	GO:0006886	intracellular protein transport	EHD1	IMP		Human	PMID:15020713
Biological Process	GO:0034383	low-density lipoprotein particle clearance	Ehd1	IMP		Mouse	MGI:MGI:3711403|PMID:17451652
Biological Process	GO:0031175	neuron projection development	Ehd1	IMP		Rat	PMID:23572513|RGD:8554201
Biological Process	GO:0010886	positive regulation of cholesterol storage	Ehd1	IMP		Mouse	MGI:MGI:3711403|PMID:17451652
Biological Process	GO:2001137	positive regulation of endocytic recycling	Ehd1	IMP		Mouse	MGI:MGI:5487527|PMID:21177873
Biological Process	GO:1901741	positive regulation of myoblast fusion	Ehd1	IMP		Mouse	MGI:MGI:5487527|PMID:21177873
Biological Process	GO:0010976	positive regulation of neuron projection development	Ehd1	IMP		Rat	PMID:23572513|RGD:8554201
Biological Process	GO:0051260	protein homooligomerization	EHD1	IPI	UniProtKB:Q9H4M9	Human	PMID:17233914
Biological Process	GO:0061512	protein localization to cilium	EHD1	IMP		Human	PMID:25686250

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern