Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EHD2
  • Mouse genes Ehd2
  • Rat genes Ehd2
  • Zfish genes ehd2a,ehd2b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ehd2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0042802	identical protein binding	Ehd2	IPI	UniProtKB:Q8BH64	Mouse	MGI:MGI:3762310|PMID:17914359
Molecular Function	GO:0042802	identical protein binding	Ehd2	IPI	UniProtKB:Q8BH64	Mouse	MGI:MGI:5645194|PMID:24508342
Molecular Function	GO:0005515	protein binding	EHD2	IPI	UniProtKB:Q9H223	Human	PMID:17233914
Molecular Function	GO:0005515	protein binding	EHD2	IPI	UniProtKB:Q9H4M9	Human	PMID:17233914
Molecular Function	GO:0005515	protein binding	EHD2	IPI	UniProtKB:Q9NZN3	Human	PMID:17233914
Molecular Function	GO:0005515	protein binding	EHD2	IPI	UniProtKB:Q9NZN4	Human	PMID:17233914
Molecular Function	GO:0005515	protein binding	EHD2	IPI	UniProtKB:Q03135	Human	PMID:25588833
Molecular Function	GO:0005515	protein binding	Ehd2	IPI	PR:Q8C8R3	Mouse	PMID:20489164
Molecular Function	GO:0005515	protein binding	Ehd2	IPI	PR:Q99JY9	Mouse	PMID:15247266
Molecular Function	GO:0019904	protein domain specific binding	Ehd2	IDA		Mouse	PMID:14676205
Cellular Component	GO:0005901	caveola	EHD2	IDA		Human	PMID:24013648
Cellular Component	GO:0005901	caveola	Ehd2	IDA		Mouse	MGI:MGI:5645194|PMID:24508342
Cellular Component	GO:0005829	cytosol	Ehd2	IDA		Mouse	MGI:MGI:5645194|PMID:24508342
Cellular Component	GO:0070062	extracellular exosome	EHD2	HDA		Human	PMID:19056867
Cellular Component	GO:0019898	extrinsic component of membrane	Ehd2	IDA		Mouse	MGI:MGI:5645194|PMID:24508342
Cellular Component	GO:0045171	intercellular bridge	EHD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0016020	membrane	Ehd2	IDA		Mouse	PMID:14676205
Cellular Component	GO:0015630	microtubule cytoskeleton	EHD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Ehd2	IDA		Mouse	PMID:20489164
Cellular Component	GO:0005886	plasma membrane	EHD2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005886	plasma membrane	Ehd2	IDA		Mouse	MGI:MGI:5487527|PMID:21177873
Cellular Component	GO:0005886	plasma membrane	Ehd2	IDA		Mouse	PMID:15247266
Cellular Component	GO:0055038	recycling endosome membrane	EHD2	IDA		Human	PMID:17233914
Biological Process	GO:0030866	cortical actin cytoskeleton organization	Ehd2	IDA		Mouse	PMID:15247266
Biological Process	GO:0032456	endocytic recycling	EHD2	IGI	UniProtKB:G5ECC3,UniProtKB:G5EEU7	Human	PMID:17233914
Biological Process	GO:0006897	endocytosis	Ehd2	IDA		Mouse	PMID:14676205
Biological Process	GO:0006897	endocytosis	Ehd2	IDA		Mouse	PMID:15247266
Biological Process	GO:0097320	plasma membrane tubulation	Ehd2	IDA		Mouse	MGI:MGI:5645194|PMID:24508342
Biological Process	GO:2001137	positive regulation of endocytic recycling	Ehd2	IMP		Mouse	MGI:MGI:5487527|PMID:21177873
Biological Process	GO:1901741	positive regulation of myoblast fusion	Ehd2	IMP		Mouse	MGI:MGI:5487527|PMID:21177873
Biological Process	GO:0072659	protein localization to plasma membrane	Ehd2	IDA		Mouse	MGI:MGI:5487527|PMID:21177873

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern