Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EHD3
  • Mouse genes Ehd3
  • Rat genes Ehd3
  • Zfish genes ehd3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ehd3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EHD3	IPI	UniProtKB:Q9H223	Human	PMID:17233914
Molecular Function	GO:0005515	protein binding	EHD3	IPI	UniProtKB:Q9H4M9	Human	PMID:17233914
Molecular Function	GO:0005515	protein binding	EHD3	IPI	UniProtKB:Q9NZN4	Human	PMID:17233914
Molecular Function	GO:0005515	protein binding	EHD3	IPI	UniProtKB:Q8N3F8	Human	PMID:19864458
Molecular Function	GO:0005515	protein binding	EHD3	IPI	UniProtKB:Q01484	Human	PMID:20489164
Molecular Function	GO:0005515	protein binding	EHD3	IPI	UniProtKB:Q9H4M9	Human	PMID:26226295
Molecular Function	GO:0005515	protein binding	EHD3	IPI	UniProtKB:Q9QXY6	Human	PMID:26226295
Molecular Function	GO:0005515	protein binding	EHD3	IPI	UniProtKB:Q8N3F8	Human	PMID:27189942
Molecular Function	GO:0005515	protein binding	EHD3	IPI	UniProtKB:Q9P2R3	Human	PMID:27189942
Molecular Function	GO:0005515	protein binding	EHD3	IPI	UniProtKB:Q15041	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHD3	IPI	UniProtKB:Q9H4M9	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Ehd3	IPI	UniProtKB:Q9NZN3	Mouse	MGI:MGI:5787759|PMID:26226295
Molecular Function	GO:0005515	protein binding	Ehd3	IPI	PR:Q8C8R3	Mouse	PMID:20489164
Molecular Function	GO:0005515	protein binding	Ehd3	IPI	PR:Q9WVK4	Mouse	PMID:12121420
Cellular Component	GO:0020018	ciliary pocket membrane	EHD3	IDA		Human	PMID:25686250
Cellular Component	GO:0005737	cytoplasm	Ehd3	IDA		Mouse	MGI:MGI:5009397|PMID:17251388
Cellular Component	GO:0030139	endocytic vesicle	Ehd3	IDA		Mouse	PMID:12121420
Cellular Component	GO:0005925	focal adhesion	EHD3	HDA		Human	PMID:21423176
Cellular Component	GO:0043209	myelin sheath	Ehd3	HDA		Mouse	MGI:MGI:3834050|PMID:17634366
Cellular Component	GO:0048471	perinuclear region of cytoplasm	Ehd3	IDA		Mouse	PMID:20489164
Cellular Component	GO:0055038	recycling endosome membrane	EHD3	IDA		Human	PMID:17233914
Biological Process	GO:0060271	cilium assembly	EHD3	IMP		Human	PMID:25686250
Biological Process	GO:0060271	cilium assembly	Ehd3	IMP		Mouse	MGI:MGI:5770034|PMID:25686250
Biological Process	GO:0060271	cilium assembly	ehd3	IMP		Zfish	PMID:25686250|ZFIN:ZDB-PUB-150429-18
Biological Process	GO:0034498	early endosome to Golgi transport	EHD3	IMP		Human	PMID:19139087
Biological Process	GO:0032456	endocytic recycling	EHD3	IDA		Human	PMID:17233914
Biological Process	GO:0090160	Golgi to lysosome transport	EHD3	IMP		Human	PMID:19139087
Biological Process	GO:1901387	positive regulation of voltage-gated calcium channel activity	Ehd3	IMP		Mouse	MGI:MGI:5770033|PMID:25825486
Biological Process	GO:0051260	protein homooligomerization	EHD3	IPI	UniProtKB:Q9NZN3	Human	PMID:17233914
Biological Process	GO:0072659	protein localization to plasma membrane	EHD3	IGI	UniProtKB:Q8C8R3	Human	PMID:20489164
Biological Process	GO:0072659	protein localization to plasma membrane	Ehd3	IMP		Mouse	PMID:20489164
Biological Process	GO:0001881	receptor recycling	EHD3	IMP		Human	PMID:21791287
Biological Process	GO:1903779	regulation of cardiac conduction	Ehd3	IMP		Mouse	MGI:MGI:5770033|PMID:25825486
Biological Process	GO:0086036	regulation of cardiac muscle cell membrane potential	EHD3	IGI	UniProtKB:Q8C8R3	Human	PMID:20489164
Biological Process	GO:0086036	regulation of cardiac muscle cell membrane potential	Ehd3	IMP		Mouse	PMID:20489164
Biological Process	GO:0055117	regulation of cardiac muscle contraction	Ehd3	IMP		Mouse	MGI:MGI:5770033|PMID:25825486
Biological Process	GO:1903358	regulation of Golgi organization	EHD3	IMP		Human	PMID:19139087

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern