Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EHMT1
  • Mouse genes Ehmt1
  • Rat genes Ehmt1
  • Zfish genes ehmt1a,ehmt1b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ehmt1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070742	C2H2 zinc finger domain binding	Ehmt1	IPI	UniProtKB:O88286	Mouse	MGI:MGI:3690291|PMID:16702210
Molecular Function	GO:0046976	histone H3K27 methyltransferase activity	Ehmt1	IDA		Mouse	MGI:MGI:3575040|PMID:15774718
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	EHMT1	IDA		Human	PMID:12004135
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	Ehmt1	IMP		Mouse	MGI:MGI:3826717|PMID:18818694
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	Ehmt1	IDA		Mouse	MGI:MGI:3575040|PMID:15774718
Molecular Function	GO:0008168	methyltransferase activity	EHMT1	IDA		Human	PMID:12004135
Molecular Function	GO:0002039	p53 binding	EHMT1	IPI	UniProtKB:P04637	Human	PMID:20118233
Molecular Function	GO:0005515	protein binding	EHMT1	IPI	UniProtKB:O95785	Human	PMID:16702210
Molecular Function	GO:0005515	protein binding	EHMT1	IPI	UniProtKB:Q9Y232	Human	PMID:19061646
Molecular Function	GO:0005515	protein binding	EHMT1	IPI	UniProtKB:Q99549	Human	PMID:20871592
Molecular Function	GO:0005515	protein binding	EHMT1	IPI	UniProtKB:Q04206	Human	PMID:21131967
Molecular Function	GO:0005515	protein binding	EHMT1	IPI	UniProtKB:Q04207	Human	PMID:21131967
Molecular Function	GO:0005515	protein binding	EHMT1	IPI	UniProtKB:Q99549	Human	PMID:26496610
Molecular Function	GO:0005515	protein binding	Ehmt1	IPI	UniProtKB:Q9Z148	Mouse	MGI:MGI:3826717|PMID:18818694
Molecular Function	GO:0005515	protein binding	Ehmt1	IPI	UniProtKB:Q04207	Mouse	MGI:MGI:4946475|PMID:21131967
Molecular Function	GO:0005515	protein binding	Ehmt1	IPI	UniProtKB:A2AUY4	Mouse	MGI:MGI:6446038|PMID:32103178
Molecular Function	GO:0005515	protein binding	Ehmt1	IPI	UniProtKB:A2A935-3	Mouse	MGI:MGI:5559375|PMID:24196706
Molecular Function	GO:0005515	protein binding	Ehmt1	IPI	UniProtKB:Q6PR54	Mouse	MGI:MGI:5584328|PMID:24735877
Molecular Function	GO:0005515	protein binding	Ehmt1	IPI	UniProtKB:O88286	Mouse	MGI:MGI:3690291|PMID:16702210
Molecular Function	GO:0005515	protein binding	Ehmt1	IPI	UniProtKB:Q9Z148	Mouse	MGI:MGI:3575040|PMID:15774718
Molecular Function	GO:0005515	protein binding	Ehmt1	IPI	UniProtKB:Q62315	Mouse	MGI:MGI:4441247|PMID:19010785
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	EHMT1	IDA		Human	PMID:20118233
Molecular Function	GO:0001222	transcription corepressor binding	EHMT1	IPI	UniProtKB:Q96JN0	Human	PMID:29628311
Cellular Component	GO:0016604	nuclear body	EHMT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	EHMT1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	EHMT1	IDA		Human	PMID:19144645
Cellular Component	GO:0005634	nucleus	Ehmt1	IDA		Mouse	MGI:MGI:3575040|PMID:15774718
Biological Process	GO:0006325	chromatin organization	EHMT1	IDA		Human	PMID:12004135
Biological Process	GO:0006306	DNA methylation	Ehmt1	IDA		Mouse	MGI:MGI:3826717|PMID:18818694
Biological Process	GO:0140718	facultative heterochromatin formation	Ehmt1	IDA		Mouse	MGI:MGI:4441247|PMID:19010785
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	Ehmt1	IMP		Mouse	MGI:MGI:4946475|PMID:21131967
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ehmt1	IMP		Mouse	PMID:17392792
Biological Process	GO:0018027	peptidyl-lysine dimethylation	EHMT1	IDA		Human	PMID:20118233
Biological Process	GO:0018027	peptidyl-lysine dimethylation	Ehmt1	IMP		Mouse	MGI:MGI:3575040|PMID:15774718
Biological Process	GO:0018026	peptidyl-lysine monomethylation	Ehmt1	IMP		Mouse	MGI:MGI:3575040|PMID:15774718
Biological Process	GO:0120162	positive regulation of cold-induced thermogenesis	Ehmt1	IMP		Mouse	MGI:MGI:5559375|PMID:24196706
Biological Process	GO:0045995	regulation of embryonic development	Ehmt1	IMP		Mouse	MGI:MGI:3575040|PMID:15774718
Biological Process	GO:0060992	response to fungicide	Ehmt1	IEP		Rat	PMID:22496781|RGD:9588300

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern