Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EHMT2
  • Mouse genes Ehmt2
  • Rat genes Ehmt2
  • Zfish genes ehmt2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Ehmt2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0070742	C2H2 zinc finger domain binding	EHMT2	IPI	UniProtKB:O88286	Human	PMID:16702210
Molecular Function	GO:0070742	C2H2 zinc finger domain binding	Ehmt2	IPI	UniProtKB:O88286	Mouse	MGI:MGI:3690291|PMID:16702210
Molecular Function	GO:0046976	histone H3K27 methyltransferase activity	Ehmt2	IDA		Mouse	MGI:MGI:3575040|PMID:15774718
Molecular Function	GO:0046976	histone H3K27 methyltransferase activity	Ehmt2	IMP		Mouse	PMID:17212651
Molecular Function	GO:0140759	histone H3K56 methyltransferase activity	EHMT2	IMP		Human	PMID:22387026
Molecular Function	GO:0140759	histone H3K56 methyltransferase activity	Ehmt2	IMP		Mouse	MGI:MGI:5424084|PMID:22387026
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	Ehmt2	EXP		Mouse	MGI:MGI:5770074|PMID:17707230
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	Ehmt2	IMP		Mouse	MGI:MGI:3826717|PMID:18818694
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	Ehmt2	IDA		Mouse	MGI:MGI:3575040|PMID:15774718
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	Ehmt2	IMP		Mouse	PMID:17212651
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	Ehmt2	IMP		Mouse	PMID:15788566
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	Ehmt2	IMP	MGI:MGI:3718790	Mouse	PMID:17599069
Molecular Function	GO:0046974	histone H3K9 methyltransferase activity	Ehmt2	IDA		Mouse	PMID:19144645
Molecular Function	GO:0002039	p53 binding	EHMT2	IPI	UniProtKB:P04637	Human	PMID:20118233
Molecular Function	GO:1990841	promoter-specific chromatin binding	EHMT2	IDA		Human	PMID:23918802
Molecular Function	GO:1990841	promoter-specific chromatin binding	Ehmt2	IDA		Mouse	PMID:22770845
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:O60568	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q5JSZ5	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q9Y4X4	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q07120	Human	PMID:16287849
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q13547	Human	PMID:16287849
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q99684	Human	PMID:16287849
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:O95785	Human	PMID:16702210
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q9NQX1	Human	PMID:17636019
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:O94776	Human	PMID:18451879
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q9P2R6	Human	PMID:18451879
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q9UBC3	Human	PMID:18953337
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q9Y232	Human	PMID:19061646
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q9H4L7	Human	PMID:21549307
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q13547	Human	PMID:23752268
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q92831	Human	PMID:24492005
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:O60568	Human	PMID:25910212
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:O60315	Human	PMID:26028330
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:O60568	Human	PMID:26028330
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:O94776	Human	PMID:26028330
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:P23771	Human	PMID:26028330
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q13330	Human	PMID:26028330
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q13547	Human	PMID:26028330
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q9BTC8	Human	PMID:26028330
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:O60341-1	Human	PMID:26751641
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:A0A0S2Z5X4	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q99801-1	Human	PMID:27339988
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q96JM2	Human	PMID:27705803
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q6P1J9	Human	PMID:29774127
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:O60568	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:P20592	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:P38919	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:P57682	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q14119	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q6VMQ6-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q7Z3Z2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q96BV0	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q96EG3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q96JB3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q96JM2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q9BSU3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q9NWS9-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q9UM22	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q9Y4X4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:P57682	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	EHMT2	IPI	UniProtKB:Q9Y4X4	Human	PMID:35140242
Molecular Function	GO:0005515	protein binding	Ehmt2	IPI	UniProtKB:O88286	Mouse	MGI:MGI:3690291|PMID:16702210
Molecular Function	GO:0005515	protein binding	Ehmt2	IPI	UniProtKB:Q5DW34	Mouse	MGI:MGI:3575040|PMID:15774718
Molecular Function	GO:0005515	protein binding	Ehmt2	IPI	UniProtKB:Q96EQ9,UniProtKB:Q9WTK2	Mouse	MGI:MGI:6355525|PMID:27932493
Molecular Function	GO:0005515	protein binding	Ehmt2	IPI	UniProtKB:Q62315	Mouse	MGI:MGI:4441247|PMID:19010785
Molecular Function	GO:0005515	protein binding	Ehmt2	IPI	UniProtKB:Q07279	Mouse	MGI:MGI:4366183|PMID:19822740
Molecular Function	GO:0005515	protein binding	Ehmt2	IPI	UniProtKB:Q6PR54	Mouse	MGI:MGI:5584328|PMID:24735877
Molecular Function	GO:0005515	protein binding	Ehmt2	IPI	UniProtKB:O88508-1|UniProtKB:O88509	Mouse	MGI:MGI:5915592|PMID:18953337
Molecular Function	GO:0005515	protein binding	Ehmt2	IPI	UniProtKB:Q3TYX3	Mouse	MGI:MGI:6709288|PMID:28250819
Molecular Function	GO:0005515	protein binding	Ehmt2	IPI	UniProtKB:O70237	Mouse	MGI:MGI:3629243|PMID:16688220
Molecular Function	GO:0005515	protein binding	Ehmt2	IPI	UniProtKB:P09631	Mouse	MGI:MGI:5566549|PMID:24532712
Molecular Function	GO:0005515	protein binding	Ehmt2	IPI	UniProtKB:Q5DW34	Mouse	MGI:MGI:3826717|PMID:18818694
Molecular Function	GO:0005515	protein binding	Ehmt2	IPI	RGD:620979	Rat	PMID:22880885|RGD:9588218
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	EHMT2	IDA		Human	PMID:19144645
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	EHMT2	IDA		Human	PMID:20118233
Molecular Function	GO:0016279	protein-lysine N-methyltransferase activity	Ehmt2	IDA		Mouse	PMID:19144645
Molecular Function	GO:0000977	RNA polymerase II transcription regulatory region sequence-specific DNA binding	Ehmt2	IDA		Mouse	PMID:21402781
Molecular Function	GO:0001222	transcription corepressor binding	EHMT2	IPI	UniProtKB:Q96JN0	Human	PMID:29628311
Cellular Component	GO:0000785	chromatin	EHMT2	IDA		Human	PMID:19144645
Cellular Component	GO:0016607	nuclear speck	EHMT2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	EHMT2	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	EHMT2	IDA		Human	PMID:19144645
Cellular Component	GO:0005634	nucleus	Ehmt2	IDA		Mouse	MGI:MGI:3690291|PMID:16702210
Cellular Component	GO:0005634	nucleus	Ehmt2	IDA		Mouse	MGI:MGI:6355525|PMID:27932493
Cellular Component	GO:0005634	nucleus	Ehmt2	IDA		Mouse	MGI:MGI:3575040|PMID:15774718
Cellular Component	GO:0005634	nucleus	Ehmt2	IDA		Mouse	PMID:22770845
Cellular Component	GO:0005634	nucleus	Ehmt2	IDA		Mouse	PMID:15493016
Cellular Component	GO:0005634	nucleus	Ehmt2	IDA		Rat	PMID:22880885|RGD:9588218
Biological Process	GO:0048148	behavioral response to cocaine	Ehmt2	IMP	MGI:MGI:4418499	Mouse	PMID:24584053
Biological Process	GO:0060219	camera-type eye photoreceptor cell differentiation	ehmt2	IGI	ZFIN:ZDB-MRPHLNO-100524-9,ZFIN:ZDB-MRPHLNO-161116-1	Zfish	PMID:27546533
Biological Process	GO:0060219	camera-type eye photoreceptor cell differentiation	ehmt2	IMP	ZFIN:ZDB-MRPHLNO-100524-9	Zfish	PMID:27546533
Biological Process	GO:0060219	camera-type eye photoreceptor cell differentiation	ehmt2	IGI	ZFIN:ZDB-MRPHLNO-100524-9,ZFIN:ZDB-MRPHLNO-161116-2	Zfish	PMID:27546533
Biological Process	GO:0071314	cellular response to cocaine	Ehmt2	IDA		Mouse	PMID:24584053
Biological Process	GO:0009267	cellular response to starvation	EHMT2	IDA		Human	PMID:23918802
Biological Process	GO:0071466	cellular response to xenobiotic stimulus	Ehmt2	IDA		Rat	PMID:22880885|RGD:9588218
Biological Process	GO:0006306	DNA methylation	Ehmt2	IDA		Mouse	MGI:MGI:3826717|PMID:18818694
Biological Process	GO:0010424	DNA methylation on cytosine within a CG sequence	Ehmt2	IMP		Mouse	PMID:17212651
Biological Process	GO:0031017	exocrine pancreas development	ehmt2	IGI	ZFIN:ZDB-MRPHLNO-050809-5,ZFIN:ZDB-MRPHLNO-100524-10	Zfish	PMID:19946145
Biological Process	GO:0009566	fertilization	Ehmt2	IMP	MGI:MGI:3718790	Mouse	PMID:17599069
Biological Process	GO:0034968	histone lysine methylation	EHMT2	IDA		Human	PMID:19144645
Biological Process	GO:0007616	long-term memory	Ehmt2	IMP		Rat	PMID:22514307|RGD:9589166
Biological Process	GO:1902902	negative regulation of autophagosome assembly	Ehmt2	IMP		Mouse	PMID:23918802
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	EHMT2	IDA		Human	PMID:19144645
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ehmt2	IMP	MGI:MGI:4418499	Mouse	PMID:24584053
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ehmt2	IMP		Mouse	PMID:23918802
Biological Process	GO:0000122	negative regulation of transcription by RNA polymerase II	Ehmt2	IMP		Mouse	PMID:17392792
Biological Process	GO:0022008	neurogenesis	ehmt2	IGI	ZFIN:ZDB-MRPHLNO-100524-11,ZFIN:ZDB-MRPHLNO-100524-9	Zfish	PMID:19946145
Biological Process	GO:0022008	neurogenesis	ehmt2	IGI	ZFIN:ZDB-MRPHLNO-060214-6,ZFIN:ZDB-MRPHLNO-100524-9	Zfish	PMID:19946145
Biological Process	GO:0048665	neuron fate specification	Ehmt2	IMP	MGI:MGI:4418499	Mouse	PMID:24584053
Biological Process	GO:0048599	oocyte development	Ehmt2	IMP	MGI:MGI:3718790	Mouse	PMID:17599069
Biological Process	GO:0035265	organ growth	Ehmt2	IMP	MGI:MGI:3718790	Mouse	PMID:17599069
Biological Process	GO:0018027	peptidyl-lysine dimethylation	EHMT2	IDA		Human	PMID:20118233
Biological Process	GO:0036166	phenotypic switching	Ehmt2	IMP	MGI:MGI:4418499	Mouse	PMID:24584053
Biological Process	GO:0006479	protein methylation	Ehmt2	IMP	MGI:MGI:3718790	Mouse	PMID:17599069
Biological Process	GO:0044030	regulation of DNA methylation	Ehmt2	IDA		Rat	PMID:22880885|RGD:9588218
Biological Process	GO:0006275	regulation of DNA replication	EHMT2	IMP		Human	PMID:22387026
Biological Process	GO:0006275	regulation of DNA replication	Ehmt2	IMP		Mouse	MGI:MGI:5424084|PMID:22387026
Biological Process	GO:0051570	regulation of histone H3-K9 methylation	ehmt2	IGI	ZFIN:ZDB-MRPHLNO-050809-5,ZFIN:ZDB-MRPHLNO-100524-10	Zfish	PMID:19946145
Biological Process	GO:0031060	regulation of histone methylation	Ehmt2	IMP		Rat	PMID:22514307|RGD:9589166
Biological Process	GO:0006357	regulation of transcription by RNA polymerase II	Ehmt2	IMP	MGI:MGI:3718790	Mouse	PMID:17599069
Biological Process	GO:0045471	response to ethanol	Ehmt2	IEP		Rat	PMID:23413810|RGD:9491848
Biological Process	GO:0060992	response to fungicide	Ehmt2	IEP		Rat	PMID:22496781|RGD:9588300
Biological Process	GO:0031667	response to nutrient levels	Ehmt2	IEP		Rat	PMID:19001366|RGD:9589167
Biological Process	GO:0007286	spermatid development	Ehmt2	IMP	MGI:MGI:3718790	Mouse	PMID:17599069
Biological Process	GO:0007130	synaptonemal complex assembly	Ehmt2	IMP	MGI:MGI:3718790	Mouse	PMID:17599069

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern