Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EIF3E
  • Mouse genes Eif3e
  • Rat genes Eif3e
  • Zfish genes eif3ea,eif3eb
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eif3e

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0045296	cadherin binding	EIF3E	HDA		Human	PMID:25468996
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:P14373	Human	PMID:10504338
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q99613	Human	PMID:10504338
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q59EK9	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q99814	Human	PMID:17324924
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q04637	Human	PMID:17468741
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q09161	Human	PMID:17468741
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q14152	Human	PMID:17468741
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q9HAU5	Human	PMID:17468741
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:O15371	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:P55884	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q99613	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q9UBQ5	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q9Y262	Human	PMID:18599441
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:P55884	Human	PMID:18628297
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q9UBQ5	Human	PMID:19748344
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q9Y262	Human	PMID:19748344
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:O15371	Human	PMID:20890303
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q9Y6E2	Human	PMID:21745818
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q9Q2G4	Human	PMID:22190034
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:O15371	Human	PMID:23623729
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q99613	Human	PMID:23623729
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q9UBQ5	Human	PMID:23623729
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q9Y262	Human	PMID:23623729
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:O15371,UniProtKB:Q04637,UniProtKB:Q99613	Human	PMID:24092755
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q8IUH5	Human	PMID:24705354
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q59EK9	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q8IY42	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:O15371	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q99613	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q9UBQ5	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q9Y262	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:P04233	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q8IY21	Human	PMID:30833792
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q8IY42	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:O95208-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q59EK9-3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q5JXC2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q5T749	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q6NTE8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q86U28	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q96MX3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:P02489	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:P17252	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:P61981	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q15047-2	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q5SUL5	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q8TAP4-4	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF3E	IPI	UniProtKB:Q92993	Human	PMID:32814053
Molecular Function	GO:0003723	RNA binding	EIF3E	HDA		Human	PMID:22681889
Molecular Function	GO:0003743	translation initiation factor activity	EIF3E	IDA		Human	PMID:17581632
Molecular Function	GO:0003743	translation initiation factor activity	EIF3E	IDA		Human	PMID:25849773
Molecular Function	GO:0003743	translation initiation factor activity	Eif3e	IDA		Mouse	MGI:MGI:3843422|PMID:17581632
Molecular Function	GO:0044325	transmembrane transporter binding	Eif3e	IPI	RGD:2245	Rat	PMID:23737983|RGD:10755504
Cellular Component	GO:0005737	cytoplasm	EIF3E	IDA		Human	PMID:10504338
Cellular Component	GO:0005829	cytosol	EIF3E	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3E	IPI		Human	PMID:17322308
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3E	IDA		Human	PMID:17322308
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3E	IDA		Human	PMID:17581632
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3E	IDA		Human	PMID:18599441
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3E	IDA		Human	PMID:25849773
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	EIF3E	IDA		Human	PMID:9295280
Cellular Component	GO:0005852	eukaryotic translation initiation factor 3 complex	Eif3e	IDA		Mouse	MGI:MGI:3843422|PMID:17581632
Cellular Component	GO:0070062	extracellular exosome	EIF3E	HDA		Human	PMID:20458337
Cellular Component	GO:0016020	membrane	EIF3E	HDA		Human	PMID:19946888
Cellular Component	GO:0005634	nucleus	EIF3E	IDA		Human	PMID:10504338
Cellular Component	GO:0016605	PML body	EIF3E	IDA		Human	PMID:10504338
Cellular Component	GO:0014069	postsynaptic density	Eif3e	IDA		Mouse	PMID:25211037
Cellular Component	GO:0014069	postsynaptic density	Eif3e	EXP		Mouse	PMID:25211037
Biological Process	GO:0043010	camera-type eye development	eif3ea	IMP	ZFIN:ZDB-GENO-071228-1	Zfish	ZFIN:ZDB-PUB-071023-1
Biological Process	GO:0043010	camera-type eye development	eif3ea	IMP	ZFIN:ZDB-MRPHLNO-071228-2	Zfish	ZFIN:ZDB-PUB-071023-1
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	eif3ea	IMP	ZFIN:ZDB-GENO-071228-1	Zfish	ZFIN:ZDB-PUB-071023-1
Biological Process	GO:0048703	embryonic viscerocranium morphogenesis	eif3ea	IMP	ZFIN:ZDB-MRPHLNO-071228-2	Zfish	ZFIN:ZDB-PUB-071023-1
Biological Process	GO:0006874	intracellular calcium ion homeostasis	Eif3e	IMP		Rat	PMID:23737983|RGD:10755504
Biological Process	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	EIF3E	IMP		Human	PMID:17468741
Biological Process	GO:0043473	pigmentation	eif3ea	IMP	ZFIN:ZDB-MRPHLNO-071228-2	Zfish	ZFIN:ZDB-PUB-071023-1
Biological Process	GO:0043473	pigmentation	eif3ea	IMP	ZFIN:ZDB-GENO-071228-1	Zfish	ZFIN:ZDB-PUB-071023-1
Biological Process	GO:0090316	positive regulation of intracellular protein transport	Eif3e	IMP		Rat	PMID:23737983|RGD:10755504
Biological Process	GO:1902416	positive regulation of mRNA binding	EIF3E	IPI	UniProtKB:O15371,UniProtKB:Q04637,UniProtKB:Q99613	Human	PMID:24092755
Biological Process	GO:0045727	positive regulation of translation	EIF3E	IPI	UniProtKB:O15371,UniProtKB:Q04637,UniProtKB:Q99613	Human	PMID:24092755
Biological Process	GO:0006413	translational initiation	EIF3E	IDA		Human	PMID:17581632
Biological Process	GO:0006413	translational initiation	Eif3e	IDA		Mouse	MGI:MGI:3843422|PMID:17581632

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern