Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EIF4A3
  • Mouse genes Eif4a3l2
  • Rat genes Eif4a3
  • Zfish genes eif4a3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eif4a3l2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005524	ATP binding	EIF4A3	IDA		Human	PMID:10523622
Molecular Function	GO:0003729	mRNA binding	EIF4A3	IDA		Human	PMID:22961380
Molecular Function	GO:0008143	poly(A) binding	EIF4A3	IDA		Human	PMID:10523622
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q04637	Human	PMID:10523622
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:P61326	Human	PMID:14730019
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9Y5S9	Human	PMID:14730019
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:O15234	Human	PMID:14973490
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9BZI7	Human	PMID:15361857
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:O15234	Human	PMID:16170325
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:P61326	Human	PMID:16170325
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q6PII3	Human	PMID:16189514
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:O15234	Human	PMID:16209946
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:P61326	Human	PMID:16209946
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9BZI7	Human	PMID:16209946
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9Y5S9	Human	PMID:16209946
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:O15234	Human	PMID:16601204
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:P61326	Human	PMID:16601204
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9BZI7	Human	PMID:16601204
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9Y5S9	Human	PMID:16601204
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:O15234	Human	PMID:16923391
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:O15234	Human	PMID:16931718
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:O15234	Human	PMID:18066079
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:P61326	Human	PMID:18066079
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9BY77	Human	PMID:18423201
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:O15234	Human	PMID:19410547
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:P61326	Human	PMID:19410547
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9BZI7	Human	PMID:19410547
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9Y5S9	Human	PMID:19410547
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9Y5S9	Human	PMID:19417104
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:O15234	Human	PMID:19478851
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:P61326	Human	PMID:19478851
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9BZI7	Human	PMID:19478851
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9Y2W1	Human	PMID:20123736
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:O15234	Human	PMID:20479275
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q5C9Z4	Human	PMID:21576267
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9HCG8	Human	PMID:22365833
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:O15234	Human	PMID:22522823
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9HCG8	Human	PMID:22961380
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:O15234	Human	PMID:23084401
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:P61326	Human	PMID:23084401
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9BZI7	Human	PMID:23084401
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9HCG8	Human	PMID:23084401
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9Y2W1	Human	PMID:23084401
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9Y5S9	Human	PMID:23084401
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9HCG8	Human	PMID:23236153
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q14147	Human	PMID:25220460
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q53EL6	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q96GN5	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q53F19	Human	PMID:26382858
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:O15234	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9HCG8	Human	PMID:29997244
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9H7Z3	Human	PMID:30538148
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:O14744	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:O15234	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:P14373	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:P25786	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:P50221	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:P55039	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:P62487	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:P98169	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q04864-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q3KNR5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q53EL6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q6P9H4	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q6PII3	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q8TBB1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q96D03	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q96KQ7	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9GZT8	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9H257-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9H8Y1	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9NRD5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9NRI5-2	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF4A3	IPI	UniProtKB:Q9NY93	Human	PMID:32296183
Molecular Function	GO:0043021	ribonucleoprotein complex binding	Eif4a3	IDA		Rat	PMID:17632064|RGD:10044262
Molecular Function	GO:0003723	RNA binding	EIF4A3	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	EIF4A3	HDA		Human	PMID:22681889
Molecular Function	GO:0003724	RNA helicase activity	EIF4A3	IDA		Human	PMID:10523622
Molecular Function	GO:0035613	RNA stem-loop binding	Eif4a3	IDA		Rat	PMID:21685449|RGD:10044260
Molecular Function	GO:0035368	selenocysteine insertion sequence binding	Eif4a3	IDA		Rat	PMID:21685449|RGD:10044260
Molecular Function	GO:0045182	translation regulator activity	Eif4a3	IDA		Rat	PMID:17632064|RGD:10044262
Molecular Function	GO:0045182	translation regulator activity	Eif4a3	IMP		Rat	PMID:17632064|RGD:10044262
Cellular Component	GO:0071013	catalytic step 2 spliceosome	EIF4A3	IDA		Human	PMID:11991638
Cellular Component	GO:0071013	catalytic step 2 spliceosome	EIF4A3	IDA		Human	PMID:22961380
Cellular Component	GO:0005737	cytoplasm	EIF4A3	IDA		Human	PMID:10523622
Cellular Component	GO:0005737	cytoplasm	Eif4a3	IDA		Rat	PMID:17632064|RGD:10044262
Cellular Component	GO:0030425	dendrite	Eif4a3	IDA		Rat	PMID:17632064|RGD:10044262
Cellular Component	GO:0035145	exon-exon junction complex	EIF4A3	IPI		Human	PMID:16931718
Cellular Component	GO:0035145	exon-exon junction complex	EIF4A3	IDA		Human	PMID:16601204
Cellular Component	GO:0035145	exon-exon junction complex	eif4a3	IDA		Zfish	PMID:32502192
Cellular Component	GO:0098978	glutamatergic synapse	Eif4a3	IDA		Rat	PMID:17632064|RGD:10044262
Cellular Component	GO:0098978	glutamatergic synapse	Eif4a3	IMP		Rat	PMID:17632064|RGD:10044262
Cellular Component	GO:0016020	membrane	EIF4A3	HDA		Human	PMID:19946888
Cellular Component	GO:0043025	neuronal cell body	Eif4a3	IDA		Rat	PMID:17632064|RGD:10044262
Cellular Component	GO:0005654	nucleoplasm	EIF4A3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	EIF4A3	IDA		Human	PMID:29301961
Cellular Component	GO:0005634	nucleus	Eif4a3	IDA		Rat	PMID:17632064|RGD:10044262
Cellular Component	GO:1990904	ribonucleoprotein complex	Eif4a3	IDA		Rat	PMID:17632064|RGD:10044262
Cellular Component	GO:0071006	U2-type catalytic step 1 spliceosome	EIF4A3	IDA		Human	PMID:29301961
Biological Process	GO:0008306	associative learning	Eif4a3	IEP		Rat	PMID:22982623|RGD:10044257
Biological Process	GO:1990416	cellular response to brain-derived neurotrophic factor stimulus	Eif4a3	IEP		Rat	PMID:17632064|RGD:10044262
Biological Process	GO:0072715	cellular response to selenite ion	Eif4a3	IEP		Rat	PMID:19716792|RGD:10045552
Biological Process	GO:0048701	embryonic cranial skeleton morphogenesis	EIF4A3	IMP		Human	PMID:24360810
Biological Process	GO:0035640	exploration behavior	Eif4a3	IEP		Rat	PMID:22982623|RGD:10044257
Biological Process	GO:0000398	mRNA splicing, via spliceosome	EIF4A3	IDA		Human	PMID:29301961
Biological Process	GO:0090394	negative regulation of excitatory postsynaptic potential	Eif4a3	IMP		Rat	PMID:17632064|RGD:10044262
Biological Process	GO:0010629	negative regulation of gene expression	Eif4a3	IMP		Rat	PMID:17632064|RGD:10044262
Biological Process	GO:1904570	negative regulation of selenocysteine incorporation	Eif4a3	IDA		Rat	PMID:19716792|RGD:10045552
Biological Process	GO:1904570	negative regulation of selenocysteine incorporation	Eif4a3	IDA		Rat	PMID:21685449|RGD:10044260
Biological Process	GO:1904574	negative regulation of selenocysteine insertion sequence binding	Eif4a3	IDA		Rat	PMID:19716792|RGD:10045552
Biological Process	GO:0017148	negative regulation of translation	EIF4A3	IDA		Human	PMID:10523622
Biological Process	GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	EIF4A3	IMP		Human	PMID:16209946
Biological Process	GO:0045727	positive regulation of translation	EIF4A3	IMP		Human	PMID:18423201
Biological Process	GO:1902415	regulation of mRNA binding	Eif4a3	IDA		Rat	PMID:19716792|RGD:10045552
Biological Process	GO:2000622	regulation of nuclear-transcribed mRNA catabolic process, nonsense-mediated decay	EIF4A3	IDA		Human	PMID:19478851
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	Eif4a3	IDA		Rat	PMID:17632064|RGD:10044262
Biological Process	GO:0099578	regulation of translation at postsynapse, modulating synaptic transmission	Eif4a3	IMP		Rat	PMID:17632064|RGD:10044262
Biological Process	GO:0014070	response to organic cyclic compound	Eif4a3	IEP		Rat	PMID:17632064|RGD:10044262

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern