Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EIF4EBP2
  • Mouse genes Eif4ebp2
  • Rat genes Eif4ebp2
  • Zfish genes eif4ebp2
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eif4ebp2

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0008190	eukaryotic initiation factor 4E binding	Eif4ebp2	IMP		Mouse	MGI:MGI:4820682|PMID:20347422
Molecular Function	GO:0005515	protein binding	EIF4EBP2	IPI	UniProtKB:P06730	Human	PMID:15153109
Molecular Function	GO:0005515	protein binding	EIF4EBP2	IPI	UniProtKB:P06730	Human	PMID:16271312
Molecular Function	GO:0005515	protein binding	EIF4EBP2	IPI	UniProtKB:P06730	Human	PMID:24207126
Molecular Function	GO:0005515	protein binding	EIF4EBP2	IPI	UniProtKB:P06730	Human	PMID:24722188
Molecular Function	GO:0005515	protein binding	EIF4EBP2	IPI	UniProtKB:P06730	Human	PMID:24981860
Molecular Function	GO:0005515	protein binding	EIF4EBP2	IPI	UniProtKB:P06730	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	EIF4EBP2	IPI	UniProtKB:P06730	Human	PMID:25533957
Molecular Function	GO:0005515	protein binding	EIF4EBP2	IPI	UniProtKB:P06730	Human	PMID:28514442
Molecular Function	GO:0005515	protein binding	EIF4EBP2	IPI	UniProtKB:P06730	Human	PMID:31515488
Molecular Function	GO:0005515	protein binding	EIF4EBP2	IPI	UniProtKB:P06730	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	Eif4ebp2	IPI	UniProtKB:Q8N122	Mouse	MGI:MGI:4820682|PMID:20347422
Molecular Function	GO:0005515	protein binding	Eif4ebp2	IPI	UniProtKB:P20415	Mouse	PMID:8939971
Molecular Function	GO:0030371	translation repressor activity	EIF4EBP2	IDA		Human	PMID:30765518
Molecular Function	GO:0030371	translation repressor activity	Eif4ebp2	IMP		Mouse	MGI:MGI:3607012|PMID:16237163
Molecular Function	GO:0030371	translation repressor activity	Eif4ebp2	IMP		Mouse	MGI:MGI:5471212|PMID:23172145
Molecular Function	GO:0030371	translation repressor activity	Eif4ebp2	IMP		Mouse	MGI:MGI:4820682|PMID:20347422
Cellular Component	GO:0043232	intracellular non-membrane-bounded organelle	EIF4EBP2	IDA		Human	PMID:30765518
Cellular Component	GO:0071598	neuronal ribonucleoprotein granule	EIF4EBP2	IDA		Human	PMID:30765518
Cellular Component	GO:0098794	postsynapse	Eif4ebp2	IDA		Rat	PMID:11756682|RGD:13702327
Biological Process	GO:0008286	insulin receptor signaling pathway	Eif4ebp2	IDA		Mouse	PMID:8939971
Biological Process	GO:0007613	memory	Eif4ebp2	IMP		Mouse	MGI:MGI:3607012|PMID:16237163
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Eif4ebp2	IMP		Mouse	MGI:MGI:5471212|PMID:23172145
Biological Process	GO:0050804	modulation of chemical synaptic transmission	Eif4ebp2	IDA		Mouse	MGI:MGI:4820682|PMID:20347422
Biological Process	GO:0045947	negative regulation of translational initiation	EIF4EBP2	IDA		Human	PMID:30765518
Biological Process	GO:0045947	negative regulation of translational initiation	Eif4ebp2	IMP		Mouse	MGI:MGI:4820682|PMID:20347422
Biological Process	GO:0045947	negative regulation of translational initiation	Eif4ebp2	IMP		Mouse	MGI:MGI:3607012|PMID:16237163
Biological Process	GO:0045947	negative regulation of translational initiation	Eif4ebp2	IMP		Mouse	MGI:MGI:5471212|PMID:23172145
Biological Process	GO:0048167	regulation of synaptic plasticity	Eif4ebp2	IMP		Mouse	MGI:MGI:3607012|PMID:16237163
Biological Process	GO:0048167	regulation of synaptic plasticity	Eif4ebp2	IMP		Mouse	MGI:MGI:4820682|PMID:20347422
Biological Process	GO:0035176	social behavior	Eif4ebp2	IMP		Mouse	MGI:MGI:5471212|PMID:23172145
Biological Process	GO:0035176	social behavior	Eif4ebp2	IMP		Mouse	MGI:MGI:3768180|PMID:17029989
Biological Process	GO:0035176	social behavior	Eif4ebp2	IMP		Mouse	MGI:MGI:4820682|PMID:20347422
Biological Process	GO:0031929	TOR signaling	Eif4ebp2	IMP		Mouse	MGI:MGI:4820682|PMID:20347422
Biological Process	GO:0031929	TOR signaling	Eif4ebp2	IDA		Mouse	PMID:8939971

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern