Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EIF5B
  • Mouse genes Eif5b
  • Rat genes Eif5b
  • Zfish genes eif5b
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eif5b

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EIF5B	IPI	UniProtKB:O14602	Human	PMID:12569173
Molecular Function	GO:0005515	protein binding	EIF5B	IPI	UniProtKB:P14921	Human	PMID:20195357
Molecular Function	GO:0005515	protein binding	EIF5B	IPI	UniProtKB:O43933	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF5B	IPI	UniProtKB:O76024	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	EIF5B	IPI	UniProtKB:P28799	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	Eif5b	IPI	RGD:2120	Rat	PMID:8667030|RGD:631943
Molecular Function	GO:0003723	RNA binding	EIF5B	HDA		Human	PMID:22658674
Molecular Function	GO:0003723	RNA binding	EIF5B	HDA		Human	PMID:22681889
Molecular Function	GO:0003743	translation initiation factor activity	EIF5B	IDA		Human	PMID:10432305
Cellular Component	GO:0005737	cytoplasm	EIF5B	IDA		Human	PMID:12426392
Cellular Component	GO:0045202	synapse	Eif5b	IDA		Mouse	PMID:25211037
Cellular Component	GO:0045202	synapse	Eif5b	EXP		Mouse	PMID:25211037
Biological Process	GO:0006446	regulation of translational initiation	EIF5B	IDA		Human	PMID:10432305

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern