Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes EIF6
  • Mouse genes Eif6
  • Rat genes Eif6
  • Zfish genes eif6
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Eif6

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0005515	protein binding	EIF6	IPI	UniProtKB:P62424,UniProtKB:Q15633,UniProtKB:Q9HCE1,UniProtKB:Q9UKV8,UniProtKB:Q9UPY3	Human	PMID:17507929
Molecular Function	GO:0005515	protein binding	EIF6	IPI	UniProtKB:P68404	Human	PMID:21665150
Molecular Function	GO:0005515	protein binding	EIF6	IPI	UniProtKB:P19525	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	EIF6	IPI	UniProtKB:Q96C10	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	EIF6	IPI	UniProtKB:Q9Y6K5	Human	PMID:21903422
Molecular Function	GO:0005515	protein binding	EIF6	IPI	UniProtKB:Q16612	Human	PMID:22365962
Molecular Function	GO:0005515	protein binding	EIF6	IPI	UniProtKB:Q08AM6	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF6	IPI	UniProtKB:Q6FHY5	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	EIF6	IPI	UniProtKB:Q8IXL7-2	Human	PMID:32296183
Molecular Function	GO:0043022	ribosome binding	EIF6	IDA		Human	PMID:21536732
Cellular Component	GO:0005737	cytoplasm	EIF6	IDA		Human	PMID:12426392
Cellular Component	GO:0070062	extracellular exosome	EIF6	HDA		Human	PMID:19056867
Cellular Component	GO:0070062	extracellular exosome	EIF6	HDA		Human	PMID:23533145
Cellular Component	GO:0005882	intermediate filament	Eif6	IDA		Mouse	PMID:9374518
Cellular Component	GO:0005638	lamin filament	Eif6	IDA		Mouse	PMID:9374518
Cellular Component	GO:0005654	nucleoplasm	EIF6	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	EIF6	IDA		Human	PMID:12426392
Cellular Component	GO:0045202	synapse	Eif6	IDA		Mouse	PMID:25211037
Cellular Component	GO:0045202	synapse	Eif6	EXP		Mouse	PMID:25211037
Biological Process	GO:0042256	cytosolic ribosome assembly	EIF6	IMP		Human	PMID:21536732
Biological Process	GO:0035195	miRNA-mediated gene silencing	EIF6	IMP		Human	PMID:17507929
Biological Process	GO:0035278	miRNA-mediated gene silencing by inhibition of translation	EIF6	IMP		Human	PMID:17507929
Biological Process	GO:0045727	positive regulation of translation	Eif6	IMP		Mouse	MGI:MGI:5699484|PMID:26383020
Biological Process	GO:0042304	regulation of fatty acid biosynthetic process	Eif6	IMP		Mouse	MGI:MGI:5699484|PMID:26383020
Biological Process	GO:0006110	regulation of glycolytic process	Eif6	IMP		Mouse	MGI:MGI:5699484|PMID:26383020
Biological Process	GO:0045652	regulation of megakaryocyte differentiation	Eif6	IMP		Mouse	MGI:MGI:5780495|PMID:26391622
Biological Process	GO:2000377	regulation of reactive oxygen species metabolic process	Eif6	IMP		Mouse	MGI:MGI:5780495|PMID:26391622
Biological Process	GO:0032868	response to insulin	Eif6	IMP		Mouse	MGI:MGI:5699484|PMID:26383020

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern