Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ELK1
  • Mouse genes Elk1
  • Rat genes Elk1
  • Zfish genes elk1
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Elk1

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003682	chromatin binding	Elk1	IDA		Rat	PMID:18768922|RGD:7488907
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ELK1	IDA		Human	PMID:12750007
Molecular Function	GO:0003700	DNA-binding transcription factor activity	ELK1	IDA		Human	PMID:14970218
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Elk1	IDA		Mouse	PMID:12473665
Molecular Function	GO:0003690	double-stranded DNA binding	Elk1	IDA		Rat	PMID:11557580|RGD:628487
Molecular Function	GO:0030374	nuclear receptor coactivator activity	ELK1	IMP		Human	PMID:31146003
Molecular Function	GO:0005515	protein binding	ELK1	IPI	UniProtKB:P27361	Human	PMID:16291755
Molecular Function	GO:0005515	protein binding	ELK1	IPI	UniProtKB:P63165	Human	PMID:17036045
Molecular Function	GO:0005515	protein binding	ELK1	IPI	UniProtKB:P63279	Human	PMID:17036045
Molecular Function	GO:0005515	protein binding	ELK1	IPI	UniProtKB:Q9UI95	Human	PMID:17296730
Molecular Function	GO:0005515	protein binding	ELK1	IPI	UniProtKB:P63165	Human	PMID:23395904
Molecular Function	GO:0005515	protein binding	ELK1	IPI	UniProtKB:P63279	Human	PMID:23395904
Molecular Function	GO:0005515	protein binding	ELK1	IPI	UniProtKB:P27361	Human	PMID:25241761
Molecular Function	GO:0005515	protein binding	ELK1	IPI	UniProtKB:O00358	Human	PMID:27852061
Molecular Function	GO:0005515	protein binding	ELK1	IPI	UniProtKB:P05067	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ELK1	IPI	UniProtKB:Q06787-7	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ELK1	IPI	UniProtKB:Q16236	Human	PMID:32911434
Molecular Function	GO:0005515	protein binding	Elk1	IPI	UniProtKB:P30275	Mouse	MGI:MGI:3621584|PMID:16549787
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ELK1	IDA		Human	PMID:12750007
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	Elk1	IDA		Rat	PMID:11557580|RGD:628487
Molecular Function	GO:0061629	RNA polymerase II-specific DNA-binding transcription factor binding	ELK1	IPI	UniProtKB:P28069	Human	PMID:26612202
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ELK1	IDA		Human	PMID:28473536
Molecular Function	GO:0000976	transcription cis-regulatory region binding	ELK1	IDA		Human	PMID:31146003
Cellular Component	GO:0043679	axon terminus	Elk1	IDA		Rat	PMID:9412502|RGD:7488913
Cellular Component	GO:0005737	cytoplasm	Elk1	IDA		Rat	PMID:9412502|RGD:7488913
Cellular Component	GO:0030425	dendrite	Elk1	IDA		Rat	PMID:16549787|RGD:7488911
Cellular Component	GO:0005739	mitochondrion	Elk1	IDA		Rat	PMID:16549787|RGD:7488911
Cellular Component	GO:0043025	neuronal cell body	Elk1	IDA		Rat	PMID:16549787|RGD:7488911
Cellular Component	GO:0005654	nucleoplasm	ELK1	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	ELK1	IDA		Human	PMID:20018936
Cellular Component	GO:0005634	nucleus	Elk1	IDA		Rat	PMID:9412502|RGD:7488913
Biological Process	GO:0071480	cellular response to gamma radiation	Elk1	IDA		Rat	PMID:17949253|RGD:7488908
Biological Process	GO:0071396	cellular response to lipid	Elk1	IDA		Rat	PMID:18768922|RGD:7488907
Biological Process	GO:0071394	cellular response to testosterone stimulus	Elk1	IEP		Rat	PMID:14766003|RGD:7488909
Biological Process	GO:0006351	DNA-templated transcription	Elk1	IDA		Mouse	MGI:MGI:2450214|PMID:12473665
Biological Process	GO:0010467	gene expression	Elk1	IMP		Mouse	PMID:31877385
Biological Process	GO:0001889	liver development	Elk1	IMP		Mouse	PMID:31877385
Biological Process	GO:0030324	lung development	Elk1	IMP		Mouse	PMID:31877385
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ELK1	IDA		Human	PMID:15790681
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ELK1	IDA		Human	PMID:17296730
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	ELK1	IMP		Human	PMID:31146003
Biological Process	GO:0045893	positive regulation of DNA-templated transcription	Elk1	IDA		Mouse	PMID:15896720
Biological Process	GO:1901216	positive regulation of neuron death	Elk1	IMP		Rat	PMID:16549787|RGD:7488911
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ELK1	IDA		Human	PMID:12750007
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ELK1	IDA		Human	PMID:14970218
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ELK1	IMP		Human	PMID:22065586
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	Elk1	IDA		Rat	PMID:19029245|RGD:8553977
Biological Process	GO:0006355	regulation of DNA-templated transcription	Elk1	IDA		Mouse	PMID:12473665
Biological Process	GO:0071774	response to fibroblast growth factor	Elk1	IDA		Rat	PMID:17156131|RGD:10054080
Biological Process	GO:0009416	response to light stimulus	Elk1	IDA		Rat	PMID:10383826|RGD:7488912

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern