Comparative GO Graph (mouse, human, rat, zebrafish)

• Source: Alliance of Genome Resources

Graphs for Molecular Function, Cellular Component, Biological Process generated Fri Mar 10 16:36:22 2023.

Complete table of the annotations represented in this image is provided below.

Graphs display curated GO classifications for mouse, human, rat and zebrafish orthologs annotated from the biomedical literature.

• This class contains
  • Human genes ELK3
  • Mouse genes Elk3
  • Rat genes Elk3
  • Zfish genes elk3
• Annotations are indicated with nodes colored by organism: Human, Mouse, Rat, Zfish
• Relations between GO terms are indicated by colored edges "is_a"; "part_of"; "regulates"; "positively_regulates"; "negatively_regulates"
• GO annotations: Human from GOA; Mouse from MGI; Rat from RGD; Zebrafish from ZFIN.
• Only experimental annotations are displayed: EXP, IDA, IEP, IGI, IMP, IPI, HTP, HDA, HMP, HGI, HEP. Evidence codes are listed at the bottom of the page.

Molecular Function

Cellular Component

Biological Process

Full set of experimental annotations for Human-Rat-Zebrafish genes considered orthologs of Mouse in the Alliance stringent orthology set Elk3

Category	ID	Classification term	Gene	Evidence	Inferred from	Organism	Reference
Molecular Function	GO:0003677	DNA binding	Elk3	IDA		Mouse	PMID:12975317
Molecular Function	GO:0001228	DNA-binding transcription activator activity, RNA polymerase II-specific	ELK3	IDA		Human	PMID:12788937
Molecular Function	GO:0003700	DNA-binding transcription factor activity	Elk3	IDA		Mouse	PMID:12975317
Molecular Function	GO:0001227	DNA-binding transcription repressor activity, RNA polymerase II-specific	ELK3	IDA		Human	PMID:12933792
Molecular Function	GO:0005515	protein binding	ELK3	IPI	UniProtKB:P16333	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	ELK3	IPI	UniProtKB:P27986	Human	PMID:17474147
Molecular Function	GO:0005515	protein binding	ELK3	IPI	UniProtKB:P27986	Human	PMID:25416956
Molecular Function	GO:0005515	protein binding	ELK3	IPI	UniProtKB:P46108	Human	PMID:26871637
Molecular Function	GO:0005515	protein binding	ELK3	IPI	UniProtKB:Q02446	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ELK3	IPI	UniProtKB:Q99471	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ELK3	IPI	UniProtKB:Q9NP55	Human	PMID:32296183
Molecular Function	GO:0005515	protein binding	ELK3	IPI	UniProtKB:Q13449	Human	PMID:32814053
Molecular Function	GO:0005515	protein binding	ELK3	IPI	UniProtKB:Q9BVL2	Human	PMID:32814053
Molecular Function	GO:0032422	purine-rich negative regulatory element binding	ELK3	IDA		Human	PMID:12933792
Molecular Function	GO:0000978	RNA polymerase II cis-regulatory region sequence-specific DNA binding	ELK3	IDA		Human	PMID:12788937
Molecular Function	GO:1990837	sequence-specific double-stranded DNA binding	ELK3	IDA		Human	PMID:28473536
Cellular Component	GO:0005739	mitochondrion	ELK3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005654	nucleoplasm	ELK3	IDA		Human	GO_REF:0000052
Cellular Component	GO:0005634	nucleus	Elk3	IDA		Mouse	PMID:12975317
Biological Process	GO:0001525	angiogenesis	Elk3	IMP	MGI:MGI:2182950	Mouse	PMID:12975317
Biological Process	GO:0045892	negative regulation of DNA-templated transcription	ELK3	IDA		Human	PMID:12933792
Biological Process	GO:0045944	positive regulation of transcription by RNA polymerase II	ELK3	IDA		Human	PMID:12788937
Biological Process	GO:0006355	regulation of DNA-templated transcription	Elk3	IDA		Mouse	PMID:12975317
Biological Process	GO:0042060	wound healing	Elk3	IMP	MGI:MGI:2182950	Mouse	PMID:12975317

Gene Ontology Evidence Code Abbreviations:

  EXP Inferred from experiment

  IDA Inferred from direct assay

  IEP Inferred from expression pattern

  IGI Inferred from genetic interaction

  IMP Inferred from mutant phenotype

  IPI Inferred from physical interaction

  HTP Inferred from High Throughput Experiment

  HDA Inferred from High Throughput Direct Assay

  HMP Inferred from High Throughput Mutant Phenotype

  HGI Inferred from High Throughput Genetic Interaction

  HEP Inferred from High Throughput Expression Pattern